Product image of Lincocin (Lincomycin) supplied by GNH India

Lincocin

Active Ingredient:
Lincomycin
Origin:
EU

Lincocin (Lincomycin)

Lincomycin, the active ingredient in Lincocin, is a lincosamide presented as an injectable solution for intravenous use. It treats bacterial infections such as skin and soft‑tissue infections, bone and joint infections, intra‑abdominal infections, and respiratory tract infections in both adult and pediatric patients as prescribed by a healthcare professional.

GNH India supplies Lincocin as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, with a focus on quality assurance, regulatory compliance, and reliable cold‑chain logistics for injectable products.

Manufacturer / TM Owner

Pfizer S.A.

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

  • Lincocin (lincomycin) is employed for bacterial infections affecting various organ systems.
  • Skin and soft tissue infections: resolves cellulitis and wound infections caused by susceptible Gram‑positive bacteria.
  • Bone and joint infections: treats osteomyelitis and septic arthritis due to lincomycin‑sensitive organisms.
  • Intra‑abdominal infections: eradicates mixed aerobic and anaerobic pathogens in peritonitis and postoperative abdominal infections.
  • Respiratory tract infections: indicated for pneumonia and bronchitis caused by susceptible strains.

How It Works

  • Lincomycin exerts its antibacterial effect by binding to the 50S subunit of the bacterial ribosome. This interaction blocks the translocation step of protein synthesis, preventing elongation of the peptide chain. By inhibiting bacterial protein production, the drug halts bacterial growth and leads to a bacteriostatic effect against susceptible Gram‑positive and certain anaerobic organisms. The binding site is distinct from that of macrolides, reducing cross‑resistance, and the effect is concentration‑dependent.

Side Effects

Lincomycin may be associated with a range of adverse reactions, varying from mild to severe.

Common Side Effects

  • Nausea: mild to moderate feeling of sickness that may be transient.
  • Diarrhea: loose, watery stools that can lead to dehydration if severe.
  • Injection site pain or erythema: local discomfort, redness, or swelling at the intravenous insertion point.

Serious or Rare Side Effects

  • Clostridioides difficile‑associated colitis: severe, potentially life‑threatening diarrhea caused by overgrowth of C. difficile bacteria.
  • Severe allergic reaction (anaphylaxis): rapid onset of hives, facial swelling, bronchospasm, and possible circulatory collapse.
  • Hepatic dysfunction (elevated transaminases): abnormal increase in liver enzymes indicating possible liver injury.

Patients should report any persistent or severe symptoms to their healthcare provider promptly.

Precautions & Warnings

When using lincomycin, several precautionary measures should be observed to minimize risks.

  • Renal function assessment: evaluate creatinine clearance before initiating therapy.
  • Hepatic monitoring: check liver enzymes periodically during treatment.
  • Hypersensitivity screening: discontinue immediately if rash, itching, or anaphylaxis occurs.
  • Pregnancy considerations: use only when benefits outweigh potential risks in pregnancy.
  • Elderly dose adjustment: consider reduced dosing or increased monitoring in older patients.
  • Store at 2-8°C: keep refrigerated, protect from light, do not freeze or shake.

Avoid Interactions

Lincomycin can interact with other medicines, affecting efficacy or safety.

Major Interactions (Avoid)

  • Neuromuscular blocking agents: may potentiate muscle weakness during anesthesia.
  • Erythromycin: antagonistic effect reducing antibacterial activity.
  • Clindamycin: cross‑resistance may diminish therapeutic effect.

Moderate Interactions (Monitor Closely)

  • Warfarin: lincomycin may increase INR, requiring closer coagulation monitoring.
  • Oral contraceptives: possible reduction in hormonal efficacy, advise backup contraception.
  • Nephrotoxic drugs: concurrent use may increase risk of renal impairment.

Frequently Asked Questions

Lincocin contains lincomycin, an injectable antibacterial indicated for treatment of certain bacterial infections such as skin and soft‑tissue infections, bone and joint infections, intra‑abdominal infections, and respiratory tract infections caused by susceptible organisms. It is prescribed by qualified healthcare professionals.

Lincomycin binds to the 50S subunit of bacterial ribosomes, blocking the translocation step of protein synthesis. This inhibition prevents elongation of the peptide chain, producing a bacteriostatic effect against susceptible Gram‑positive and anaerobic bacteria.

The dosage of Lincocin is determined by the prescribing clinician based on the type and severity of infection, patient weight, renal and hepatic function, and local antimicrobial guidelines. The prescriber sets the appropriate dose and infusion rate.

Lincomycin is classified as pregnancy category B, indicating no evidence of risk in animal studies and a lack of well‑controlled studies in pregnant women. It may be used during pregnancy only if the potential benefit justifies the potential risk. Use while breastfeeding should be considered carefully, as the drug is excreted in milk.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity of Lincocin. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details—including cold‑chain handling for injectables—and the necessary import documentation.

The primary alternative to lincomycin is clindamycin, another lincosamide with a similar spectrum of activity. Lincomycin may have a slightly different resistance profile and is often used when clindamycin resistance is suspected or when specific susceptibility data favor lincomycin. Both agents share comparable efficacy but differ in pharmacokinetic properties and dosing considerations.

Lincocin should be stored at 2‑8 °C in a refrigerator, protected from light, and must not be frozen or shaken. The vial should be kept in its original packaging until use, and any unused portion should be discarded according to local regulations after the recommended storage period.

Lincocin is supplied as an injectable solution for intravenous infusion. It is administered by a healthcare professional through a sterile IV line, typically diluted in an appropriate compatible fluid and infused over the prescribed period. Administration should follow aseptic technique and institutional infusion protocols.

The most serious risks include Clostridioides difficile‑associated colitis, severe allergic reactions such as anaphylaxis, and hepatic dysfunction indicated by elevated liver enzymes. Patients should be monitored for signs of severe diarrhea, rash, breathing difficulty, or jaundice, and treatment should be stopped immediately if these occur.

Lincocin is contraindicated in patients with a known hypersensitivity to lincomycin, other lincosamides, or any component of the formulation. It should also be avoided in individuals with a history of severe allergic reactions to related antibiotics and in patients where alternative therapies are more appropriate based on susceptibility testing.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Related Products

Other formulations containing Lincomycin

A

A
A

A
A

A
A

A

Browse all products →

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Regulatory recognitions

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.

SGS GSDP Certification

GSDP Compliant from SGS

URS ISO 9001

URS ISO 9001 Certification

FDA Maharashtra

Licensed by FDA Maharashtra

IEC License DGFT

IEC License issued by DGFT