Product image of Linezolid Dr. Eberth (Linezolid) supplied by GNH India

Linezolid Dr. Eberth

Active Ingredient:
Linezolid
Origin:
EU

Linezolid Dr. Eberth (Linezolid)

Linezolid, the active ingredient in Linezolid Dr. Eberth, is a oxazolidinone antibiotic presented as a 600 mg tablet for oral use. It treats infections caused by Gram‑positive bacteria, including methicillin‑resistant Staphylococcus aureus and vancomycin‑resistant Enterococcus, in adult patients requiring systemic therapy.

GNH India supplies Linezolid Dr. Eberth as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals worldwide.

Manufacturer / TM Owner

Dr. Friedrich Eberth Arzneimittel Gmbh

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

Linezolid is an oxazolidinone antibiotic used to treat infections caused by Gram‑positive bacteria.

  • Complicated skin and skin structure infections (cSSSI): effective against MRSA and other resistant Gram‑positive pathogens, leading to clinical cure.
  • Community‑acquired bacterial pneumonia (CABP): provides coverage for suspected MRSA involvement in adult patients.
  • Ventilator‑associated bacterial pneumonia (VABP): indicated for treatment of Gram‑positive infections in mechanically ventilated patients.

How It Works

  • Linezolid inhibits bacterial protein synthesis by binding to the 23S rRNA of the 50S ribosomal subunit, preventing formation of the initiation complex. This blocks translation, producing a bacteriostatic effect against most Gram‑positive organisms and a bactericidal effect at higher concentrations. Its unique binding site reduces cross‑resistance with other antibiotic classes.

Side Effects

Linezolid may cause a range of adverse reactions, varying in frequency and severity.

Common Side Effects

  • Nausea: mild to moderate gastrointestinal upset.
  • Diarrhea: loose stools, often self‑limiting.
  • Headache: transient cranial discomfort.
  • Metallic taste: altered taste sensation during therapy.

Serious or Rare Side Effects

  • Thrombocytopenia: significant drop in platelet count, requiring monitoring.
  • Peripheral neuropathy: sensory changes that may become irreversible with prolonged use.
  • Serotonin syndrome: risk when combined with serotonergic agents, presenting with agitation, hyperreflexia, and fever.

Precautions & Warnings

When prescribing Linezolid, clinicians should consider several safety aspects to minimize risk.

  • Renal impairment: monitor renal function and adjust therapy as needed.
  • Hepatic impairment: use with caution; assess liver enzymes regularly.
  • Concomitant serotonergic drugs: avoid due to potential serotonin syndrome.
  • Myelosuppression: perform baseline and periodic complete blood counts.
  • Pregnancy and lactation: prescribe only if benefits outweigh potential risks to fetus or infant.
  • Store at ambient temperature: keep in original packaging, protect from moisture and light.

Avoid Interactions

Linezolid interacts with several drug classes; awareness of these interactions helps prevent adverse outcomes.

Major Interactions (Avoid)

  • SSRIs, SNRIs, and other serotonergic agents: may precipitate serotonin syndrome.
  • MAO inhibitors: increase risk of hypertensive crisis.
  • Tyramine‑rich foods (e.g., aged cheeses, cured meats): can cause hypertensive episodes.

Moderate Interactions (Monitor Closely)

  • Warfarin: linezolid may potentiate anticoagulant effect, requiring INR monitoring.
  • Phenytoin: may reduce linezolid plasma concentrations, potentially decreasing efficacy.
  • Rifampin: induces metabolism leading to lower linezolid exposure, may need dose adjustment.

Frequently Asked Questions

Linezolid Dr. Eberth contains the oxazolidinone antibiotic linezolid and is indicated for the treatment of serious Gram‑positive infections such as complicated skin and skin‑structure infections, community‑acquired bacterial pneumonia, and ventilator‑associated bacterial pneumonia in adult patients.

Linezolid binds to the 23S rRNA of the bacterial 50S ribosomal subunit, blocking the formation of the initiation complex required for protein synthesis. This inhibition halts bacterial growth (bacteriostatic) and can be bactericidal at higher concentrations, targeting Gram‑positive organisms including MRSA and VRE.

The dosing regimen for Linezolid Dr. Eberth is determined by the prescribing clinician based on the specific infection, patient characteristics, and local guidelines. Healthcare professionals set the appropriate dose and duration; patients should follow the prescriber’s instructions precisely.

Linezolid should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. Limited data are available, and it crosses the placenta. While small amounts are found in breast milk, breastfeeding is generally not recommended unless the benefit to the infant outweighs the risk.

To order, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including cold‑chain if needed) and necessary import documentation.

Compared with beta‑lactams or glycopeptides, linezolid offers oral bioavailability comparable to intravenous administration, allowing seamless switch to oral therapy. It is active against many resistant Gram‑positive strains, such as MRSA and VRE, where some alternatives may lack efficacy. However, it lacks activity against Gram‑negative organisms and has a distinct safety profile that requires monitoring.

Linezolid Dr. Eberth tablets should be stored at ambient temperature, below 25 °C, in the original container to protect from moisture and light. Keep the product out of reach of children and avoid exposure to extreme temperatures or humidity.

Linezolid Dr. Eberth is supplied as oral tablets that are taken by mouth with or without food. The tablet can be swallowed whole; crushing or chewing is not required. In clinical settings where oral administration is not feasible, an intravenous formulation of linezolid may be used under medical supervision.

The most serious risks include thrombocytopenia, which can lead to bleeding; peripheral neuropathy, which may become irreversible with prolonged therapy; and serotonin syndrome when combined with serotonergic drugs. Patients should be monitored regularly for blood count changes and neurological symptoms, and any serotonergic agents should be avoided.

Linezolid is contraindicated in patients with known hypersensitivity to linezolid or any component of the formulation. It should also be avoided in individuals taking monoamine oxidase inhibitors, serotonergic agents, or those with a history of severe serotonin syndrome. Caution is advised in patients with significant hepatic or renal impairment, and it is not recommended for use in pregnant or breastfeeding women unless absolutely necessary.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.