Product image of Lino (Lisinopril) supplied by GNH India

Lino

Active Ingredient:
Lisinopril
Origin:
EU

Lino (Lisinopril)

Lisinopril, the active ingredient in Lino, is an ACE inhibitor presented as an oral dosage form for oral use. It is prescribed to manage high blood pressure, support heart failure treatment, and improve outcomes after a myocardial infarction in adult patients.

GNH India supplies Lino as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Ratiopharm Gmbh

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Indications & Clinical Uses

Lisinopril is used to treat conditions related to the renin‑angiotensin system and cardiovascular disease.

  • Hypertension: lowers elevated blood pressure and reduces cardiovascular risk.
  • Heart failure: improves symptoms and functional capacity by decreasing cardiac workload.
  • Post‑myocardial infarction: helps prevent adverse remodeling and subsequent cardiac events.

How It Works

  • Lisinopril inhibits the angiotensin‑converting enzyme (ACE), preventing the conversion of angiotensin I to the potent vasoconstrictor angiotensin II. This results in vasodilation, reduced aldosterone secretion, decreased sodium and water retention, and ultimately lower systemic vascular resistance and blood pressure.

Side Effects

Lisinopril may cause a range of adverse reactions, from mild to severe.

Common Side Effects

  • Cough: persistent dry cough.
  • Dizziness: especially when standing quickly.
  • Headache: mild to moderate intensity.
  • Fatigue: general tiredness.
  • Hyperkalemia: elevated blood potassium levels.
  • Renal function changes: slight increase in serum creatinine.

Serious or Rare Side Effects

  • Angioedema: swelling of face, lips, tongue, or airway.
  • Severe hypotension: markedly low blood pressure.
  • Acute kidney injury: rapid decline in renal function.
  • Hepatotoxicity: abnormal liver enzymes.
  • Neutropenia: low white blood cell count.
  • Stevens‑Johnson syndrome: severe skin reactions.

Precautions & Warnings

Before initiating therapy, consider the following safety measures.

  • Pregnancy: contraindicated in the second and third trimesters (Category D).
  • Breastfeeding: use only if benefits outweigh potential risks.
  • Renal impairment: adjust dose and monitor renal function.
  • Hyperkalemia: avoid concomitant potassium‑sparing agents.
  • Hypotension: monitor blood pressure after first dose.
  • Store at ambient temperature: keep below 25 °C, retain original packaging, protect from moisture.

Avoid Interactions

Lisinopril can interact with several drug classes; awareness helps prevent adverse outcomes.

Major Interactions (Avoid)

  • Aliskiren: combined use may increase risk of renal dysfunction.
  • Lithium: may raise lithium levels, risking toxicity.
  • NSAIDs (e.g., ibuprofen, naproxen): can blunt antihypertensive effect and impair renal function.

Moderate Interactions (Monitor Closely)

  • Diuretics (especially thiazides): may enhance hypotensive effect.
  • Potassium supplements or potassium‑sparing diuretics: increase risk of hyperkalemia.
  • ACE inhibitor or ARB combinations: higher incidence of renal impairment and hyperkalemia.

Frequently Asked Questions

Lino contains lisinopril, an ACE inhibitor indicated for managing hypertension, treating chronic heart failure, and improving outcomes after a myocardial infarction. It works by lowering blood pressure and reducing the workload on the heart.

Lisinopril blocks the angiotensin‑converting enzyme, decreasing the formation of angiotensin II, a powerful vasoconstrictor. This leads to blood‑vessel relaxation, reduced aldosterone release, and lower blood pressure, which eases strain on the cardiovascular system.

The appropriate dose of Lino is determined by the prescribing clinician based on the patient’s condition, response, and renal function. Dosage may be adjusted during treatment to achieve optimal blood‑pressure control.

Lisinopril is classified as pregnancy Category D and is contraindicated in the second and third trimesters because of potential fetal harm. Use during breastfeeding is only permitted if the benefit outweighs the risk to the infant.

To request Lino, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and import documentation.

Lisinopril belongs to the ACE‑inhibitor class, which directly reduces angiotensin II production. Compared with beta‑blockers or calcium‑channel blockers, ACE inhibitors often provide additional renal protection and are preferred in diabetic patients, but individual response varies.

Store Lino at ambient temperature, preferably below 25 °C. Keep the tablets in their original container, protect them from moisture and direct sunlight, and ensure the packaging remains tightly closed.

Lino is taken orally, usually once daily, with or without food. Patients should swallow the tablet whole with a full glass of water and follow the dosing schedule prescribed by their healthcare professional.

Serious risks include angioedema, which can cause swelling of the face or airway, severe hypotension, acute kidney injury, and hyperkalemia. Patients should seek immediate medical attention if they experience swelling, difficulty breathing, or a sudden drop in blood pressure.

Lino should not be used by individuals with a known hypersensitivity to lisinopril or any ACE inhibitor, patients in the second or third trimester of pregnancy, and those with a history of angioedema related to ACE‑inhibitor therapy.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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