Product image of Linolacort Hydro (Hydrocortisone) supplied by GNH India

Linolacort Hydro

Active Ingredient:
Hydrocortisone
Origin:
EU

Linolacort Hydro (Hydrocortisone)

Hydrocortisone, the active ingredient in Linolacort Hydro, is a corticosteroid presented as a topical formulation for cutaneous use. It reduces inflammation and immune responses in various skin conditions and is applied directly to the affected area.
GNH India supplies Linolacort Hydro as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Dr. August Wolff Gmbh & Co. Kg Arzneimittel

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Indications & Clinical Uses

Hydrocortisone is a topical glucocorticoid used to manage inflammatory skin disorders.

  • Atopic dermatitis: alleviates redness, itching and swelling.
  • Psoriasis: reduces plaque formation and scaling.
  • Contact dermatitis: diminishes allergic or irritant reactions on the skin.
  • Insect bite reactions: eases local inflammation and discomfort.

How It Works

  • Hydrocortisone penetrates skin cells and binds to intracellular glucocorticoid receptors, forming a complex that translocates to the nucleus. This complex interacts with glucocorticoid response elements on DNA, modulating transcription of anti‑inflammatory proteins while suppressing pro‑inflammatory cytokines, thereby decreasing edema, erythema, and immune cell activation at the site of application.

Side Effects

Topical hydrocortisone may cause local and systemic reactions, most of which are mild and reversible.

Common Side Effects

  • Burning or stinging sensation at the application site.
  • Skin dryness or peeling.
  • Pruritus or mild itching.
  • Erythema or mild redness.
  • Folliculitis or acneiform eruptions.

Serious or Rare Side Effects

  • Skin atrophy or thinning with prolonged use.
  • Striae (stretch marks) formation.
  • Hypopigmentation or discoloration of the skin.
  • Secondary bacterial, fungal or viral infection.
  • Systemic adrenal suppression when large areas are treated.
  • Allergic contact dermatitis or urticaria.

Precautions & Warnings

When using Linolacort Hydro, consider the following safety measures.

  • Avoid application on infected or open wounds: may worsen infection.
  • Limit duration of continuous use: prolonged exposure increases risk of skin atrophy.
  • Do not apply to the face, groin or axillae unless directed: higher absorption risk.
  • Use caution in children and elderly: skin is more permeable.
  • Avoid occlusive dressings unless prescribed: can enhance systemic absorption.
  • Store at room temperature below 25°C: keep in original container, protect from moisture and direct sunlight.

Avoid Interactions

Hydrocortisone can interact with other agents that affect steroid metabolism or skin integrity.

Major Interactions (Avoid)

  • Systemic corticosteroids: additive immunosuppression may increase infection risk.
  • Potent topical antibiotics or antifungals on the same area: may enhance local irritation.

Moderate Interactions (Monitor Closely)

  • CYP3A4 inhibitors (e.g., ketoconazole): may raise systemic hydrocortisone levels.
  • Skin barrier‑disrupting agents (e.g., harsh cleansers): can increase percutaneous absorption.
  • Antiviral or immunomodulatory creams: may alter therapeutic response.

Frequently Asked Questions

Linolacort Hydro is a topical hydrocortisone preparation indicated for inflammatory skin disorders such as atopic dermatitis, psoriasis, contact dermatitis and localized reactions to insect bites. It works by reducing redness, swelling and itching when applied to the affected area.

Hydrocortisone binds to glucocorticoid receptors inside skin cells, forming a complex that alters gene transcription. This leads to decreased production of pro‑inflammatory cytokines and increased synthesis of anti‑inflammatory proteins, thereby limiting edema, erythema and immune cell activity at the site of application.

The appropriate amount and frequency of Linolacort Hydro are determined by the prescribing healthcare professional based on the specific condition, severity, patient age and treatment area. Patients should follow the prescriber’s instructions and not exceed the recommended application regimen.

Safety of topical hydrocortisone in pregnancy or lactation has not been definitively established. Healthcare providers usually weigh potential benefits against risks and may recommend the lowest effective potency for the shortest duration. Patients should discuss their situation with a qualified clinician before use.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain needs) and required import documentation.

Linolacort Hydro contains hydrocortisone, a low‑ to medium‑potency corticosteroid, making it suitable for mild to moderate skin inflammation. Stronger steroids such as betamethasone or clobetasol provide greater potency but carry higher risk of side effects. Choice depends on disease severity, treatment area and physician judgment.

Store Linolacort Hydro at room temperature below 25 °C. Keep the product in its original packaging, protect it from moisture, excessive heat and direct sunlight. Do not freeze the preparation, and ensure the container is tightly closed when not in use.

Clean and gently dry the affected skin area before use. Apply a thin layer of Linolacort Hydro to the lesion and rub gently until it disappears. Wash hands after application unless the hands are being treated. Follow the prescriber’s frequency and duration instructions.

Serious risks include skin atrophy, striae formation, hypopigmentation, secondary infections, and systemic adrenal suppression when large surface areas are treated for prolonged periods. Patients should report any unusual thinning of the skin, persistent redness, or signs of infection to their healthcare provider promptly.

Linolacort Hydro should be avoided in individuals with known hypersensitivity to hydrocortisone or any formulation excipients, on untreated bacterial, viral or fungal skin infections, and on extensive broken skin unless directed by a physician. Caution is also advised for infants, young children and patients with systemic steroid therapy.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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