Product image of Lioran Centra (Dry Extract Of Passion Flower (5-7: 1), Extraction Solvent: Ethanol 50% (V/V)) supplied by GNH India

Lioran Centra

Active Ingredient:
Dry Extract Of Passion Flower (5-7: 1), Extraction Solvent: Ethanol 50% (V/V)
Origin:
EU

Lioran Centra (Dry Extract Of Passion Flower (5-7: 1), Extraction Solvent: Ethanol 50% (V/V))

Dry Extract Of Passion Flower (Passiflora spp.), the active ingredient in Lioran Centra, is a herbal supplement presented as a dry extract for oral use. It is commonly employed in complementary health practices aimed at supporting calmness and occasional sleep difficulties in adults.

GNH India supplies Lioran Centra as a licensed, GDP‑compliant international pharmaceutical supplier serving pharmacies, clinics and other healthcare providers worldwide, adhering to stringent quality standards, EU regulatory requirements and ensuring consistent product integrity and traceability.

Manufacturer / TM Owner

Cesra Arzneimittel Gmbh And Co. Kg

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Indications & Clinical Uses

Lioran Centra, a herbal supplement derived from passion flower, is used in the context of mild anxiety and sleep support.

  • Occasional insomnia: may help promote sleep onset and improve sleep quality.
  • Mild anxiety: may aid in reducing nervousness and promoting a sense of calm.
  • Restlessness: may support relaxation and reduce agitation.
  • Stress‑related tension: may assist in easing tension during stressful periods.

How It Works

  • The dry extract contains flavonoids such as vitexin and isovitexin that interact with the central nervous system, modulating GABA‑A receptor activity and influencing serotonergic pathways, which may produce mild sedative and anxiolytic effects. Additionally, the extract may affect melatonin metabolism, contributing to sleep regulation.

Side Effects

Adverse reactions reported with passion flower dry extract are generally mild and infrequent.

Common Side Effects

  • Drowsiness: feeling of increased sleepiness.
  • Dry mouth: reduced salivation.
  • Dizziness: light‑headed sensation.
  • Nausea: mild stomach upset.
  • Headache: mild cranial discomfort.
  • Fatigue: general tiredness.

Serious or Rare Side Effects

  • Allergic reaction: rash, itching or swelling.
  • Severe hypotension: marked drop in blood pressure.
  • Liver enzyme elevation: abnormal liver function tests.
  • Anaphylaxis: rare severe allergic response.
  • Persistent vomiting: ongoing nausea and vomiting.

Precautions & Warnings

When considering Lioran Centra, certain safety measures should be observed.

  • Pregnancy: safety not established; consult a healthcare professional before use.
  • Breastfeeding: unknown safety profile; avoid unless advised by a clinician.
  • Drug interactions: discuss all concurrent herbal or prescription products with a provider.
  • Medical conditions: use with caution in patients with liver disease.
  • Alcohol use: may enhance sedative effect; limit consumption.
  • Store at ambient temperature: keep in original container, protect from moisture and light.

Avoid Interactions

Passion flower extract may interact with several medication classes.

Major Interactions (Avoid)

  • CNS depressants: may cause excessive sedation when combined.
  • Benzodiazepines: risk of heightened sedative effect.

Moderate Interactions (Monitor Closely)

  • Antidepressants (SSRIs): possible additive effect on serotonin pathways.
  • Antihistamines: may increase drowsiness.
  • Alcohol: may enhance sedative properties and impair coordination.

Frequently Asked Questions

Lioran Centra is a herbal supplement containing passion flower dry extract that is traditionally used to support occasional insomnia, mild anxiety and general stress relief in adults. It is taken orally as part of a complementary health approach.

Passion flower dry extract contains flavonoids that modulate GABA‑A receptors and influence serotonergic pathways in the central nervous system. This activity can produce mild sedative and anxiolytic effects, helping to promote relaxation and improve sleep onset.

The appropriate dose of Lioran Centra is determined by the prescribing healthcare professional based on the individual’s condition, age, weight and overall health. Patients should follow the prescriber’s instructions and not exceed the recommended amount.

Safety data for passion flower dry extract in pregnancy and lactation are limited. It is advisable to avoid use during pregnancy and breastfeeding unless a qualified healthcare provider determines that the potential benefits outweigh any possible risks.

To order Lioran Centra, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Lioran Centra’s active ingredient, passion flower dry extract, is distinguished by its specific flavonoid profile that targets GABA‑A receptors. Compared with other calming herbs such as valerian or chamomile, passion flower may offer a milder sedative effect with a lower incidence of daytime drowsiness, though individual responses can vary.

Lioran Centra should be stored at ambient temperature, below 25 °C, in its original packaging. Keep the container tightly closed, protect it from moisture, direct sunlight and extreme heat to maintain product stability.

Lioran Centra is administered orally. The product is typically supplied as a dry extract that can be taken with water or another suitable beverage, following the dosage instructions provided by the prescribing clinician.

Serious risks, though rare, include allergic reactions such as rash, itching, swelling, and in extreme cases anaphylaxis. Severe hypotension has also been reported. Users should seek immediate medical attention if they experience any signs of a serious allergic response or a sudden drop in blood pressure.

Individuals with known hypersensitivity to passion flower or any of its constituents should avoid Lioran Centra. It is also not recommended for pregnant or breastfeeding women without medical advice, and for patients taking CNS depressants, benzodiazepines or other sedating medications without professional supervision.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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