Lioresal (Baclofen)

Baclofen activates GABA_B receptors in the central nervous system, decreasing the release of excitatory neurotransmitters. This inhibition reduces neuronal firing and leads to a relaxation of overly tight muscles, helping to control spasticity.

The appropriate dose of Lioresal is determined by a qualified prescriber based on the individual’s medical condition, response to therapy, and any relevant health factors. Patients should follow the dosing instructions provided by their healthcare professional.

Safety data for baclofen in pregnancy and lactation are limited. It should only be used when the potential benefit to the mother outweighs any possible risk to the fetus or infant, and this decision must be made by the prescribing clinician.

To place an order, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Compared with other muscle relaxants, baclofen’s primary action is through GABA_B receptor agonism, offering targeted reduction of spasticity. Some alternatives act via different pathways, such as central alpha‑2 agonists, and may have distinct side‑effect profiles or efficacy in specific patient groups.

Lioresal tablets should be stored at ambient temperature, below 25 °C, in their original packaging. Protect them from moisture, direct sunlight, and excessive heat to maintain product stability.

Lioresal is taken orally as a tablet, usually with a glass of water. The exact timing and whether it should be taken with food depend on the prescriber’s instructions and the patient’s tolerance.

Serious risks include seizures, severe hypotension, respiratory depression, hallucinations, and allergic reactions. Patients should seek immediate medical attention if they experience any of these symptoms while using the medication.

Lioresal is contraindicated in individuals with known hypersensitivity to baclofen or any tablet excipients, and it should be used with caution in patients with severe renal or hepatic impairment, uncontrolled epilepsy, or those taking other central nervous system depressants.