Product image of Liothyronine Sodium Strides Pharma Uk (Liothyronine Sodium) supplied by GNH India

Liothyronine Sodium Strides Pharma Uk

Active Ingredient:
Liothyronine Sodium
Origin:
EU

Liothyronine Sodium Strides Pharma Uk (Liothyronine Sodium)

Liothyronine Sodium, the active ingredient in Liothyronine Sodium Strides Pharma Uk, is a thyroid hormone presented as an oral dosage form for oral use. It treats hypothyroidism, myxedema coma, and provides thyroid hormone replacement therapy.

GNH India supplies Liothyronine Sodium Strides Pharma Uk as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Strides Pharma Uk Limited

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Indications & Clinical Uses

Liothyronine Sodium is a thyroid hormone that acts on the hypothalamic‑pituitary‑thyroid axis to restore normal metabolic function.

  • Hypothyroidism: restores deficient T3 levels, improving metabolic rate and alleviating symptoms.
  • Myxedema coma: provides rapid T3 replacement to reverse severe hypothyroid crisis.
  • Thyroid hormone replacement therapy: maintains euthyroid status in patients requiring supplemental T3.

How It Works

  • Liothyronine Sodium is a synthetic form of triiodothyronine (T3) that binds to nuclear thyroid hormone receptors, modulating gene transcription. This increases basal metabolic rate, enhances protein synthesis, and influences carbohydrate and lipid metabolism, thereby normalising the physiological effects of thyroid hormone deficiency.

Side Effects

Adverse reactions may occur with liothyronine therapy and should be monitored.

Common Side Effects

  • Palpitations or rapid heart rate.
  • Heat intolerance and excessive sweating.
  • Insomnia or difficulty sleeping.
  • Anxiety or nervousness.
  • Tremor of the hands.
  • Increased appetite.

Serious or Rare Side Effects

  • Cardiac arrhythmias, including atrial fibrillation.
  • Angina pectoris or exacerbation of coronary artery disease.
  • Heart failure in susceptible individuals.
  • Severe hyperthyroidism leading to thyroid storm.
  • Osteoporosis or accelerated bone loss with prolonged high doses.
  • Allergic reactions such as rash, urticaria, or angioedema.

Precautions & Warnings

Liothyronine Sodium requires careful clinical monitoring to minimise risks.

  • Dose titration: adjust based on serial thyroid function tests and clinical response.
  • Cardiovascular disease: monitor heart rate, rhythm, and symptoms of angina.
  • Pregnancy and lactation: use only when clearly indicated after risk‑benefit assessment.
  • Drug interactions: review concomitant medications that may alter T3 levels or cardiac effects.
  • Store below 25°C: keep in the original container, protect from moisture and direct sunlight.

Avoid Interactions

Liothyronine Sodium can interact with several medicines; awareness helps avoid adverse outcomes.

Major Interactions (Avoid)

  • Antithyroid drugs (propylthiouracil, methimazole): negate T3 activity.
  • Beta‑adrenergic agonists (e.g., albuterol): may cause excessive tachycardia.
  • Digoxin: heightened risk of toxicity due to increased cardiac sensitivity.

Moderate Interactions (Monitor Closely)

  • Estrogen‑containing oral contraceptives: raise thyroid‑binding globulin, altering free T3 levels.
  • Calcium or iron supplements: may reduce oral absorption if taken simultaneously.

Frequently Asked Questions

Liothyronine Sodium is prescribed to replace or supplement the natural thyroid hormone triiodothyronine (T3). It is used in patients with hypothyroidism, in the emergency treatment of myxedema coma, and as part of thyroid hormone replacement regimens when rapid physiological effects of T3 are required.

The drug is a synthetic form of T3 that binds to intracellular thyroid hormone receptors, influencing gene transcription. This action increases basal metabolic rate, enhances protein synthesis, and modulates carbohydrate and lipid metabolism, thereby correcting the metabolic deficits caused by insufficient endogenous thyroid hormone.

Dosing of Liothyronine Sodium is individualized. A qualified prescriber determines the appropriate dose based on the patient’s age, weight, severity of thyroid deficiency, and laboratory thyroid function results. The regimen may be adjusted over time to achieve target hormone levels.

Liothyronine Sodium should be used in pregnancy or while breastfeeding only if clearly needed. The potential benefits must outweigh any possible risks to the fetus or infant, and treatment decisions should be made in consultation with a healthcare professional experienced in managing thyroid disorders.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements), and the necessary import documentation.

Liothyronine Sodium (T3) has a faster onset of action and a shorter half‑life than levothyroxine (T4). It is often used when rapid correction of hypothyroidism is needed or in combination with levothyroxine for patients who do not achieve optimal symptom control with T4 alone. Choice of therapy depends on clinical goals and patient response.

Store the product below 25 °C in its original packaging, protecting it from moisture and direct sunlight. Do not expose the tablets or capsules to excessive heat or humidity, and keep them out of reach of children.

Liothyronine Sodium is taken orally, usually with water. The exact timing relative to meals or other medications should follow the prescribing clinician’s instructions, as food or certain supplements can affect absorption.

Serious adverse events include cardiac arrhythmias, angina, heart failure, severe hyperthyroidism (thyroid storm), and allergic reactions such as rash or angioedema. Patients should seek immediate medical attention if they experience chest pain, rapid irregular heartbeat, severe tremor, or signs of an allergic response.

Liothyronine Sodium is contraindicated in individuals with known hypersensitivity to the drug, untreated adrenal insufficiency, acute myocardial infarction, or uncontrolled cardiac disease. It should also be avoided in patients receiving high‑dose antithyroid medications unless specifically directed by a physician.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

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