Product image of Lipancrea Lipazy (Amylase, Lipase, Protease) supplied by GNH India

Lipancrea Lipazy

Active Ingredient:
Amylase, Lipase, Protease
Origin:
EU

Lipancrea Lipazy (Amylase, Lipase, Protease)

Amylase, Lipase, Protease, the active ingredients in Lipancrea Lipazy, is a pancreatic enzyme preparation presented as an oral dosage form for oral use. It aids the digestion of carbohydrates, fats and proteins in patients with exocrine pancreatic insufficiency.
GNH India supplies Lipancrea Lipazy as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Zaklady Farmaceutyczne Polpharma S.A.

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Indications & Clinical Uses

Lipancrea Lipazy provides exogenous pancreatic enzymes to support digestion in conditions characterized by enzyme deficiency.

  • Exocrine pancreatic insufficiency: improves nutrient absorption and reduces steatorrhea.
  • Cystic fibrosis‑related pancreatic insufficiency: assists in maintaining caloric intake and growth.
  • Chronic pancreatitis: alleviates maldigestion symptoms and supports weight maintenance.
  • Post‑pancreatic surgery: compensates for loss of endogenous enzyme production.

How It Works

  • Lipancrea Lipazy supplies amylase, lipase and protease that remain active in the gastrointestinal lumen, where they hydrolyze dietary carbohydrates, triglycerides and proteins into absorbable monosaccharides, fatty acids and amino acids, thereby compensating for deficient pancreatic secretion and facilitating normal digestive processes.

Side Effects

Lipancrea Lipazy may be associated with gastrointestinal and allergic reactions.

Common Side Effects

  • Abdominal discomfort or pain
  • Flatulence or bloating
  • Diarrhea or loose stools
  • Nausea or mild vomiting
  • Constipation
  • Oily or greasy stools (steatorrhea)

Serious or Rare Side Effects

  • Severe allergic reaction (anaphylaxis)
  • Fibrosing colonopathy (rare intestinal fibrosis)
  • Acute pancreatitis
  • Persistent abdominal pain requiring medical evaluation

Precautions & Warnings

Before initiating therapy, consider patient‑specific factors and monitor for adverse events.

  • Assess pancreatic insufficiency: confirm diagnosis prior to use.
  • Monitor for allergic reactions: discontinue if rash, itching or swelling occurs.
  • Adjust dose based on clinical response and nutritional status.
  • Avoid concurrent use of antacids containing aluminum or magnesium that may inactivate enzymes.
  • Store at room temperature: keep in the original container, protect from moisture and direct sunlight.

Avoid Interactions

Enzyme activity can be altered by certain medications, requiring attention to co‑administration.

Major Interactions (Avoid)

  • Proton pump inhibitors: may reduce enzyme activation in the stomach.
  • Antacids with aluminum or magnesium: can bind enzymes and diminish efficacy.

Moderate Interactions (Monitor Closely)

  • Oral contraceptives: potential alteration in hormone absorption.
  • Warfarin: monitor INR as gastrointestinal changes may affect vitamin K status.
  • Corticosteroids: may increase risk of gastrointestinal irritation.

Frequently Asked Questions

Lipancrea Lipazy is an oral pancreatic enzyme preparation containing amylase, lipase and protease. It is used to replace deficient digestive enzymes in patients with exocrine pancreatic insufficiency caused by conditions such as cystic fibrosis, chronic pancreatitis, or after pancreatic surgery, helping improve nutrient absorption and reduce gastrointestinal symptoms.

The three enzymes act together in the gastrointestinal tract: amylase breaks down complex carbohydrates into simple sugars, lipase hydrolyzes dietary fats into fatty acids and monoglycerides, and protease cleaves proteins into amino acids and peptides. By providing these enzymes externally, Lipancrea Lipazy compensates for the body's reduced pancreatic output, facilitating normal digestion.

The specific dose of Lipancrea Lipazy is individualized. A qualified prescriber determines the amount based on the patient’s age, weight, severity of enzyme deficiency, and dietary fat content. Dosage adjustments are made according to clinical response and nutritional goals, and the prescribing information provides guidance for titration.

Safety data for Lipancrea Lipazy in pregnancy and lactation are limited. The product should only be used if the potential benefit to the mother outweighs any possible risk to the fetus or infant. Healthcare providers should evaluate each case and discuss potential risks and benefits with the patient.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide. After receiving the request, the sales team will verify trade or institutional credentials, then provide pricing, availability, shipping details (including any cold‑chain requirements) and assist with import documentation.

Lipancrea Lipazy contains a balanced mix of amylase, lipase and protease, similar to other pancreatic enzyme replacements. Compared with products that contain only lipase, Lipancrea Lipazy offers broader digestive support by also addressing carbohydrate and protein digestion. Clinical efficacy and tolerability are comparable, but selection often depends on individual patient response, dosing convenience and cost considerations.

Lipancrea Lipazy should be stored at room temperature, below 25 °C. Keep the product in its original packaging, protect it from moisture and direct sunlight, and avoid exposure to extreme temperatures. Do not refrigerate or freeze unless specifically instructed by the manufacturer.

Lipancrea Lipazy is taken orally, usually with meals or snacks that contain fat, protein and carbohydrates. The tablets or capsules are swallowed whole with a sufficient amount of water. The timing of administration is important to ensure the enzymes are present in the gastrointestinal tract when food is being digested.

Serious risks, though rare, include severe allergic reactions such as anaphylaxis, fibrosing colonopathy (a form of intestinal fibrosis), and acute pancreatitis. Patients should seek immediate medical attention if they experience symptoms like difficulty breathing, swelling of the face or throat, persistent abdominal pain, or unusual changes in stool consistency.

Lipancrea Lipazy is contraindicated in individuals with known hypersensitivity to any of its enzyme components or excipients. Patients with a history of severe allergic reactions to pancreatic enzyme preparations should avoid its use. Additionally, those with active gastrointestinal obstruction or severe inflammatory bowel disease should be evaluated carefully before initiating therapy.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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