Product image of Lipidem (Omega-3-Acid Triglycerides, Soya-Bean Oil Refined, Triglycerides, Medium Chain) supplied by GNH India

Lipidem

Active Ingredient:
Omega-3-Acid Triglycerides, Soya-Bean Oil Refined, Triglycerides, Medium Chain
Origin:
EU

Lipidem (Omega-3-Acid Triglycerides, Soya-Bean Oil Refined, Triglycerides, Medium Chain)

Omega-3-acid triglycerides, the active ingredient in Lipidem, is a parenteral lipid emulsion presented as an intravenous lipid solution for intravenous use. It provides essential fatty acids and calories as an energy source for patients requiring parenteral nutrition, supporting cell membrane integrity and metabolic functions.

GNH India supplies Lipidem as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, transplant centres and oncology units worldwide.

Manufacturer / TM Owner

B.Braun Melsungen Ag

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Indications & Clinical Uses

  • Lipidem, a parenteral lipid emulsion, is used in clinical nutrition to supply essential fatty acids and calories for patients who cannot receive enteral feeding.
  • Parenteral nutrition for patients unable to receive enteral feeding: supplies calories and essential fatty acids when oral or tube feeding is not possible.
  • Provision of essential fatty acids in clinical nutrition: supports cell membrane integrity and metabolic functions in critically ill patients.
  • Prevention of essential fatty acid deficiency in long‑term parenteral therapy: maintains adequate fatty acid levels during extended intravenous feeding.

How It Works

  • After intravenous infusion, the omega-3‑acid triglycerides in Lipidem are hydrolyzed to free fatty acids that are incorporated into phospholipid membranes, providing structural components and a readily oxidizable energy source. The emulsion also delivers essential polyunsaturated fatty acids that the body cannot synthesize, thereby supporting inflammatory modulation, membrane fluidity, and overall metabolic function.

Side Effects

Lipidem may be associated with several adverse reactions following infusion.

Common Side Effects

  • Mild fever
  • Transient hypertriglyceridemia
  • Infusion site erythema

Serious or Rare Side Effects

  • Anaphylactic reaction
  • Severe hypertriglyceridemia with pancreatitis risk
  • Fat overload syndrome

Precautions & Warnings

  • When using Lipidem, clinicians should observe specific safety measures.
  • Assess triglyceride levels before initiation: monitor baseline and periodic serum triglycerides.
  • Monitor liver function tests: watch for hepatic steatosis.
  • Check for allergies to soy or egg phospholipids: avoid in known hypersensitivity.
  • Use caution in patients with pancreatitis history: evaluate risk.
  • Avoid concurrent high‑fat oral intake: may exacerbate hypertriglyceridemia.
  • Store at 2-8°C: keep refrigerated, protect from light, do not freeze or shake.

Avoid Interactions

Lipidem can interact with other medications and therapies; awareness of interaction severity is important.

Major Interactions (Avoid)

  • Concurrent use of other lipid emulsions: may cause excessive fat load.
  • High-dose propofol infusion: additive risk of hypertriglyceridemia.
  • Corticosteroids: can increase triglyceride levels.

Moderate Interactions (Monitor Closely)

  • Statins: monitor for liver enzyme changes.
  • Anticoagulants (warfarin): observe INR as lipid infusion may affect plasma protein binding.
  • Diuretics: watch electrolyte balance due to fluid shifts.

Frequently Asked Questions

Lipidem is an intravenous lipid emulsion containing omega‑3‑acid triglycerides. It is employed in parenteral nutrition to supply calories and essential fatty acids to patients who cannot receive enteral feeding, helping maintain cell membrane integrity and metabolic function during short‑ or long‑term intravenous therapy.

The omega‑3‑acid triglycerides in Lipidem are hydrolyzed after infusion to release free fatty acids that become incorporated into phospholipid membranes, providing structural components and serving as an energy substrate. They also deliver essential polyunsaturated fatty acids that cannot be synthesized by the body, supporting inflammatory modulation and cellular processes.

The dosage of Lipidem is individualized by the prescribing clinician based on the patient’s caloric needs, weight, and clinical condition. The healthcare professional determines the volume and infusion rate to achieve the required percentage of total energy intake, typically expressed as grams of lipid per kilogram per day.

Safety data for Lipidem in pregnancy and lactation are limited. Because it is administered intravenously and provides essential fatty acids, it may be used when the benefits outweigh potential risks, but the decision should be made by the treating physician in consultation with obstetric specialists.

To place an order, submit an enquiry on the Lipidem product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details—including cold‑chain handling if needed—and necessary import documentation.

Compared with traditional soybean‑oil based emulsions, Lipidem’s omega‑3‑acid triglyceride composition offers a higher proportion of polyunsaturated fatty acids, which may favorably influence inflammatory pathways and lipid profiles. However, clinical choice depends on patient‑specific factors, institutional protocols, and cost considerations.

Lipidem should be stored at 2‑8 °C, protected from light, and must not be frozen or shaken. Keep the container in its original packaging until use, and discard any product that appears discolored, separated, or has leaked.

Lipidem is given intravenously as a sterile lipid emulsion, typically infused through a dedicated line or Y‑site using an infusion pump. The rate is calculated by the clinician to meet the patient’s prescribed caloric and fatty acid goals, and the infusion set should be compatible with lipid solutions.

The most serious adverse events include anaphylactic reactions, severe hypertriglyceridemia that can precipitate pancreatitis, and fat overload syndrome, which may cause hepatic dysfunction, respiratory compromise, or coagulation abnormalities. Prompt recognition and discontinuation are essential if these events occur.

Lipidem is contraindicated in patients with known hypersensitivity to soy, egg phospholipids, or any component of the emulsion, as well as in individuals with severe hypertriglyceridemia, active pancreatitis, or uncontrolled sepsis. Use should be avoided in those with documented fat metabolism disorders unless closely monitored.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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