Product image of Lipiodol Ultra Fluid (Ethyl Esters Of Iodised Fatty Acids From Poppyseed Oil) supplied by GNH India

Lipiodol Ultra Fluid

Active Ingredient:
Ethyl Esters Of Iodised Fatty Acids From Poppyseed Oil
Origin:
EU

Lipiodol Ultra Fluid (Ethyl Esters Of Iodised Fatty Acids From Poppyseed Oil)

Ethyl Esters Of Iodised Fatty Acids From Poppyseed Oil, the active ingredient in Lipiodol Ultra Fluid, is an iodinated contrast media presented as an oil‑based liquid for intra‑arterial, intra‑lymphatic and intra‑uterine use. It provides radiopaque contrast that enhances visualization of vascular, lymphatic and hepatobiliary structures during diagnostic imaging procedures.

GNH India supplies Lipiodol Ultra Fluid as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, radiology centres, transplant centres, oncology centres, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Guerbet

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Indications & Clinical Uses

Lipiodol Ultra Fluid, an iodinated contrast medium used in diagnostic radiology, is employed for the following clinical applications:

  • Lymphangiography: enables detailed imaging of lymphatic vessels and nodes.
  • Hepatobiliary imaging: highlights bile ducts and liver parenchyma for functional assessment.
  • Embolization procedures: acts as a carrier to occlude targeted vessels during therapeutic embolization.
  • Intra‑uterine radiographic studies: provides contrast for uterine cavity evaluation and related procedures.

How It Works

  • Ethiodized oil delivers a high concentration of iodine atoms within an oil‑based carrier. The iodine atoms strongly absorb X‑ray photons, creating radiopacity that delineates vascular, lymphatic and hepatobiliary structures on imaging. The oil phase remains localized at the injection site, allowing prolonged contrast enhancement for dynamic and static radiographic studies.

Side Effects

Lipiodol Ultra Fluid may cause a range of adverse reactions, most of which are mild and transient.

Common Side Effects

  • Warmth or flushing at the injection site.
  • Mild nausea or vomiting.
  • Transient headache.
  • Brief hypotension.
  • Localized pain or discomfort.
  • Mild itching or rash.

Serious or Rare Side Effects

  • Anaphylactic or severe allergic reaction.
  • Pulmonary embolism from inadvertent vascular occlusion.
  • Significant renal impairment in susceptible patients.
  • Thyroid dysfunction due to iodine load.
  • Severe hypotension or cardiovascular collapse.
  • Persistent tissue inflammation at the injection site.

Precautions & Warnings

When using Lipiodol Ultra Fluid, clinicians should observe several safety measures:

  • Patient assessment: evaluate renal and thyroid function before administration.
  • Allergy history: screen for prior reactions to iodinated contrast agents.
  • Pregnancy: avoid unless clearly indicated, as fetal effects are unknown.
  • Concurrent iodinated agents: limit cumulative iodine exposure.
  • Monitoring: observe vital signs during and after injection for immediate reactions.
  • Store below 25°C: keep in the original container, protect from light and moisture.

Avoid Interactions

Lipiodol Ultra Fluid can interact with other medicines and procedures, requiring careful management.

Major Interactions (Avoid)

  • Thyroid hormone replacement: excess iodine may alter hormone balance.
  • Radioactive iodine therapy: iodine load can reduce therapeutic efficacy.
  • Concurrent iodinated contrast agents: increases risk of iodine toxicity.

Moderate Interactions (Monitor Closely)

  • Beta‑blockers: may mask tachycardia from contrast reactions.
  • Diuretics: affect fluid balance and renal clearance.
  • Anticoagulants: may increase bleeding risk during embolization procedures.

Frequently Asked Questions

Lipiodol Ultra Fluid is an oil‑based iodinated contrast agent used in diagnostic radiology to enhance imaging of lymphatic vessels, the hepatobiliary system, and to provide contrast during intra‑arterial embolization and intra‑uterine radiographic procedures.

The ethyl esters of iodised fatty acids contain a high density of iodine atoms that absorb X‑ray photons. When injected, the oil‑based formulation remains localized, creating a radiopaque outline of vessels or cavities, which improves visualization on X‑ray, CT or fluoroscopic studies.

The dose of Lipiodol Ultra Fluid is determined by the prescribing physician based on the specific imaging study, patient size, and clinical indication. It is administered by a qualified healthcare professional under controlled conditions.

Safety data for Lipiodol Ultra Fluid in pregnancy and lactation are limited. It should be used only if clearly needed and after careful risk‑benefit assessment by the treating physician. Breastfeeding mothers should consult their healthcare provider before use.

To order Lipiodol Ultra Fluid, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements) and necessary import documentation.

Compared with water‑soluble iodinated contrast media, Lipiodol Ultra Fluid’s oil‑based formulation provides longer-lasting vascular and lymphatic opacification, making it especially useful for lymphangiography and embolization. However, its viscosity may require specialized injection techniques and it carries a different safety profile regarding iodine load.

Lipiodol Ultra Fluid should be stored below 25 °C in its original container, protected from light and moisture. Keep the vial tightly sealed and avoid freezing. Handle with care to prevent contamination and follow standard aseptic techniques during preparation.

The product is administered by a qualified professional via intra‑arterial, intra‑lymphatic or intra‑uterine injection, depending on the intended imaging study. The oil‑based liquid is injected under imaging guidance to ensure accurate placement and optimal contrast enhancement.

Serious risks include severe allergic reactions (anaphylaxis), pulmonary embolism from inadvertent vascular occlusion, significant renal impairment in susceptible patients, and thyroid dysfunction due to iodine overload. Immediate medical attention is required if any of these events occur.

Patients with known hypersensitivity to iodinated contrast agents, uncontrolled hyperthyroidism, severe renal insufficiency, or those who are pregnant without a clear clinical indication should avoid using Lipiodol Ultra Fluid. The prescribing clinician must evaluate each case individually.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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