Product image of Lipiodol Ultra Fluid (Ethyl Esters Of Iodised Fatty Acids From Poppyseed Oil) supplied by GNH India

Lipiodol Ultra Fluid

Active Ingredient:
Ethyl Esters Of Iodised Fatty Acids From Poppyseed Oil
Origin:
EU

Lipiodol Ultra Fluid (Ethyl Esters Of Iodised Fatty Acids From Poppyseed Oil)

Ethyl esters of iodised fatty acids from poppyseed oil, the active ingredient in Lipiodol Ultra Fluid, is an iodinated oil‑based contrast agent presented as an oil‑based liquid for intraglandular, intralymphatic and intrauterine use. It provides radiopaque contrast for imaging procedures such as lymphangiography, hysterosalpingography and selected embolisation interventions.

GNH India supplies Lipiodol Ultra Fluid as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, transplant centres, oncology centres, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Guerbet

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Indications & Clinical Uses

  • Lipiodol Ultra Fluid, an iodinated oil‑based contrast medium, is used in radiographic procedures that require high‑density contrast.
  • Lymphangiography: visualises lymphatic vessels and nodes to assess obstruction or leakage.
  • Hysterosalpingography: delineates uterine cavity and fallopian tube patency for fertility evaluation.
  • Embolisation procedures: provides temporary occlusion of target vessels during therapeutic embolisation.
  • Selected intra‑arterial or intra‑venous contrast enhancement: enhances vascular imaging in specialised radiologic examinations.

How It Works

  • The ethyl esters of iodised fatty acids deliver a high concentration of iodine atoms within an oil vehicle that remains localized at the injection site. Iodine atoms strongly absorb X‑ray photons, creating a radiopaque image that highlights vascular or cavity structures during fluoroscopy, CT or digital subtraction angiography, thereby improving anatomical delineation.

Side Effects

Adverse reactions may occur following administration of Lipiodol Ultra Fluid.

Common Side Effects

  • Mild pain or burning at the injection site.
  • Transient fever or chills.
  • Nausea or vomiting.
  • Headache.
  • Skin erythema or mild rash.
  • Temporary taste alteration.

Serious or Rare Side Effects

  • Anaphylactic or severe allergic reaction.
  • Pulmonary embolism or oil‑induced lung injury.
  • Thyroid dysfunction due to iodine overload.
  • Acute renal impairment.
  • Embolic events causing tissue ischemia.
  • Severe hypotension or cardiovascular collapse.

Precautions & Warnings

Prior to use, clinicians should evaluate patient history and procedural requirements.

  • Assess iodine allergy: screen for known hypersensitivity to iodinated contrast agents.
  • Evaluate thyroid status: consider recent iodine exposure or thyroid disease.
  • Monitor renal function: avoid in patients with severe renal impairment unless benefits outweigh risks.
  • Use appropriate technique: ensure correct injection site and volume to minimise embolic risk.
  • Store at ambient temperature: keep container tightly closed, protect from light and heat, store below 25 °C.

Avoid Interactions

Lipiodol Ultra Fluid may interact with other medications that affect iodine handling or renal clearance.

Major Interactions (Avoid)

  • Lithium therapy: increased risk of lithium toxicity.
  • Radioactive iodine treatment: reduced efficacy due to iodine load.
  • Thyroid hormone replacement: potential alteration of thyroid function.

Moderate Interactions (Monitor Closely)

  • Beta‑blockers: may mask tachycardia from contrast reactions.
  • Diuretics: can affect renal clearance of iodine.
  • Anticoagulants: heightened risk of bleeding at injection sites.

Frequently Asked Questions

Lipiodol Ultra Fluid is an iodinated oil‑based contrast medium used in diagnostic imaging procedures such as lymphangiography, hysterosalpingography, and selected embolisation techniques to provide clear visualization of vascular and cavity structures.

The ethyl esters of iodised fatty acids carry iodine atoms within an oil carrier. Iodine strongly absorbs X‑ray photons, creating a radiopaque image that highlights the targeted anatomy during fluoroscopic or CT imaging, while the oil vehicle helps retain the contrast at the site of administration.

The dose of Lipiodol Ultra Fluid is determined by the prescribing radiologist or physician based on the specific imaging procedure, patient size, and clinical indication. The prescriber sets the appropriate volume and concentration for each case.

The safety of Lipiodol Ultra Fluid in pregnancy or breastfeeding has not been established. It should be used only if clearly needed and after careful risk‑benefit assessment by the treating physician.

To order, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Compared with water‑soluble iodinated contrast media, Lipiodol Ultra Fluid’s oil‑based formulation provides longer retention at the injection site, making it suitable for lymphangiography and embolisation. However, its oil nature may carry a higher risk of embolic complications, requiring careful technique.

Store the product at ambient temperature, below 25 °C, in its original sealed container. Protect it from direct sunlight, heat and moisture. Do not freeze or shake the vial before use.

The product is administered by a trained healthcare professional via intraglandular, intralymphatic, intrauterine, intra‑arterial or intra‑venous injection, depending on the intended imaging study. The specific route and volume are selected by the physician performing the procedure.

Serious risks include severe allergic reactions (anaphylaxis), pulmonary embolism or oil‑induced lung injury, thyroid dysfunction from iodine overload, and acute renal impairment. Immediate medical attention is required if any of these events occur.

Patients with a known hypersensitivity to iodinated contrast agents, uncontrolled hyperthyroidism, severe renal insufficiency, or those who have had recent radioactive iodine therapy should generally avoid Lipiodol Ultra Fluid unless the benefits outweigh the risks.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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