Product image of Lipoflex Peri (Valine, Alanine, Arginine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serine, Threonin) supplied by GNH India

Lipoflex Peri

Active Ingredient:
Valine, Alanine, Arginine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serine, Threonin
Origin:
EU

Lipoflex Peri (Valine, Alanine, Arginine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serine, Threonin)

Valine, Alanine, Arginine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serine, Threonine, the active ingredients in Lipoflex Peri, are an amino acid solution presented as an intravenous formulation for parenteral use. It supports peri‑operative protein needs in adult surgical patients.

GNH India supplies Lipoflex Peri as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals worldwide.

Manufacturer / TM Owner

B.Braun Melsungen Ag

1
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Indications & Clinical Uses

Lipoflex Peri is used as a parenteral amino acid supplement to address protein and nitrogen deficits in clinical settings.

  • Peri‑operative nutrition: helps maintain nitrogen balance and supports wound healing during and after surgery.
  • Total parenteral nutrition (TPN): provides essential amino acids when oral intake is not possible.
  • Catabolic states: supplies substrates for protein synthesis in patients with severe trauma or burns.

How It Works

  • The amino acids in Lipoflex Peri are directly available to cells after intravenous infusion, bypassing gastrointestinal absorption. They replenish intracellular pools, stimulate protein synthesis, and help restore nitrogen balance. By providing essential and non‑essential amino acids, the solution supports tissue repair, immune function, and metabolic stability during periods of increased catabolism.

Side Effects

Lipoflex Peri may be associated with infusion‑related reactions and metabolic changes.

Common Side Effects

  • Phlebitis at the infusion site: inflammation of the vein.
  • Hyperglycemia: elevated blood glucose levels, especially in diabetic patients.
  • Electrolyte disturbances: mild shifts in potassium or calcium.
  • Mild nausea or vomiting during infusion.
  • Transient fever or chills.

Serious or Rare Side Effects

  • Anaphylactic reaction: severe allergic response requiring immediate medical attention.
  • Metabolic acidosis: significant acid‑base imbalance.
  • Hyperosmolarity: excessive osmolar load leading to renal stress.
  • Severe electrolyte imbalance: dangerous potassium or calcium shifts.
  • Bacterial contamination: rare but possible infection risk if aseptic technique fails.

Precautions & Warnings

When using Lipoflex Peri, clinicians should consider patient‑specific factors and monitor for adverse events.

  • Renal function: assess creatinine clearance before infusion.
  • Hepatic impairment: adjust dosing in severe liver disease.
  • Diabetes mellitus: monitor blood glucose closely.
  • Fluid balance: avoid overload in patients with heart failure.
  • Compatibility: do not mix with calcium‑containing solutions unless verified.
  • Store at 2-8°C: keep refrigerated, protect from light, do not freeze or shake.

Avoid Interactions

Amino acid solutions can interact with other intravenous therapies, altering electrolyte or osmolar balance.

Major Interactions (Avoid)

  • Concurrent high‑potassium IV fluids: risk of hyperkalemia.
  • Calcium‑containing solutions mixed directly: precipitation risk.
  • Certain antibiotics (e.g., aminoglycosides) when co‑infused: may reduce efficacy.

Moderate Interactions (Monitor Closely)

  • Diuretics: may exacerbate electrolyte shifts.
  • Insulin therapy: increased risk of hypoglycemia if glucose not adjusted.
  • Anticoagulants: monitor coagulation parameters if large volumes are infused.

Frequently Asked Questions

Lipoflex Peri is an intravenous amino acid solution used to provide essential and non‑essential amino acids for patients who cannot meet protein needs orally. It is commonly employed in peri‑operative nutrition, total parenteral nutrition, and in clinical situations with high catabolic demand such as severe trauma or burns.

The blend delivers a balanced profile of essential and non‑essential amino acids directly into the bloodstream, bypassing the gastrointestinal tract. These amino acids become immediately available for protein synthesis, help restore nitrogen balance, support tissue repair, and maintain metabolic stability during periods of increased protein breakdown.

The dose of Lipoflex Peri is individualized by the prescribing clinician based on the patient’s weight, metabolic needs, and clinical condition. Healthcare professionals calculate the required amino acid amount and infusion rate according to established nutrition guidelines and the patient’s laboratory parameters.

Safety data for Lipoflex Peri in pregnancy and lactation are limited. It should only be used if the potential benefit to the mother outweighs any possible risk to the fetus or infant, and the decision must be made by a qualified healthcare provider.

To order Lipoflex Peri, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including cold‑chain if needed), and import documentation.

Lipoflex Peri offers a comprehensive profile of ten amino acids designed for peri‑operative and catabolic support. Compared with single‑amino‑acid formulations, it provides a more balanced substrate for protein synthesis, potentially reducing the need for multiple infusions and simplifying nutritional management.

Lipoflex Peri must be stored at 2‑8 °C, protected from light, and kept in its original packaging. Do not freeze or shake the product. Before administration, allow the solution to reach room temperature if required, and inspect for particulate matter or discoloration.

Lipoflex Peri is administered intravenously, typically via a peripheral or central venous catheter. The infusion rate is set by the prescriber based on the patient’s nutritional plan and monitored continuously for tolerance, blood glucose, and electrolyte balance.

Serious risks include anaphylactic reactions, severe electrolyte disturbances, metabolic acidosis, and bacterial contamination if aseptic technique is compromised. Prompt recognition and management of these events are essential, and patients should be monitored closely during and after infusion.

Lipoflex Peri should be avoided in patients with known hypersensitivity to any of its amino acid components, those with uncontrolled hyperkalemia, severe renal impairment without appropriate dose adjustment, or in individuals where fluid overload poses a risk, such as uncontrolled heart failure.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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