Lipoflex Peri (Valine, Alanine, Arginine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serine, Threonin)

Lipoflex Peri, an amino acid solution used in parenteral nutrition, supports patients with specific clinical needs.

• Parenteral nutrition: supplies essential amino acids to meet protein requirements when oral intake is insufficient.
• Perioperative nutritional support: enhances recovery by providing substrates for tissue repair during the surgical period.
• Amino acid supplementation in critical illness: helps maintain nitrogen balance and supports metabolic demands in critically ill patients.

• Lipoflex Peri delivers a balanced mixture of essential and non‑essential amino acids directly into the bloodstream. The amino acids serve as substrates for protein synthesis, activate mTOR signaling pathways, and replenish nitrogen stores, thereby supporting cellular repair, immune function, and overall metabolic processes during intravenous nutritional therapy.

Lipoflex Peri may be associated with infusion‑related reactions and metabolic disturbances.

Common Side Effects

• Injection site pain: mild discomfort at the catheter site.
• Hyperglycemia: transient increase in blood glucose levels.
• Electrolyte imbalance: mild shifts in potassium or sodium concentrations.
• Nausea: occasional feeling of queasiness.

Serious or Rare Side Effects

• Anaphylaxis: severe allergic reaction requiring immediate medical attention.
• Metabolic acidosis: significant acid‑base disturbance.
• Hyperammonemia: elevated ammonia levels in susceptible patients.
• Thrombophlebitis: inflammation of the vein with clot formation.

When using Lipoflex Peri, clinicians should observe several precautions to ensure patient safety.

• Assess renal function: adjust infusion in patients with impaired kidney clearance.
• Monitor blood glucose: check glucose levels regularly during therapy.
• Check liver enzymes: observe for hepatic dysfunction that may affect amino acid metabolism.
• Evaluate electrolyte status: correct abnormalities before and during infusion.
• Observe for signs of infection: maintain aseptic technique to prevent catheter‑related infections.
• Store at 2-8°C: keep refrigerated, protect from light, do not freeze or shake.

Lipoflex Peri can interact with certain medications and clinical conditions.

Major Interactions (Avoid)

• High‑dose insulin therapy: may exacerbate hypoglycemia when combined with amino acid infusion.
• Loop diuretics: increase risk of electrolyte disturbances, especially potassium loss.

Moderate Interactions (Monitor Closely)

• Corticosteroids: may augment protein catabolism, requiring dose adjustment.
• Parenteral lipid emulsions: concurrent administration can affect nitrogen balance.
• Renal replacement therapy: may remove amino acids, reducing efficacy.
• Anticoagulants: monitor clotting parameters as amino acid solutions can affect platelet function.