Product image of Lipofundin Mct/Lct (Soya-Bean Oil Refined, Triglycerides, Medium Chain) supplied by GNH India

Lipofundin Mct/Lct

Active Ingredient:
Soya-Bean Oil Refined, Triglycerides, Medium Chain
Origin:
EU

Lipofundin Mct/Lct (Soya-Bean Oil Refined, Triglycerides, Medium Chain)

Soybean oil, medium-chain triglycerides, the active ingredient in Lipofundin Mct/Lct, is an intravenous lipid emulsion presented as an emulsion for intravenous infusion use. It supplies calories and essential fatty acids to patients requiring parenteral nutrition and helps prevent essential fatty acid deficiency.

GNH India supplies Lipofundin Mct/Lct as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, transplant centres, oncology centres and pharmacies worldwide, with a focus on quality, regulatory compliance and reliable global distribution to meet the nutritional needs of critically ill patients.

Manufacturer / TM Owner

B.Braun Melsungen Ag

1
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Indications & Clinical Uses

Lipofundin Mct/Lct is used in parenteral nutrition to provide calories and essential fatty acids.

  • Parenteral nutrition in patients unable to receive enteral feeding: supplies necessary energy and fatty acids when oral or tube feeding is not feasible.
  • Prevention of essential fatty acid deficiency: delivers linoleic and alpha‑linolenic acids to avoid deficiency during prolonged intravenous feeding.
  • Support during major surgery or critical illness: provides rapid energy and membrane components to meet increased metabolic demands.

How It Works

  • The emulsion contains triglycerides composed of soybean oil and medium‑chain triglycerides. After intravenous infusion, lipases hydrolyze the triglycerides to free fatty acids, which are taken up by tissues for β‑oxidation, ATP generation and phospholipid synthesis. Medium‑chain fatty acids are rapidly oxidized, while the long‑chain soybean fatty acids supply essential linoleic and α‑linolenic acids required for cell membrane integrity and support cellular function.

Side Effects

Lipofundin Mct/Lct may be associated with several adverse reactions.

Common Side Effects

  • Hypertriglyceridemia: elevated triglyceride levels.
  • Fever or chills: transient temperature rise during infusion.
  • Infusion site reactions: erythema, pain or swelling.
  • Nausea: mild gastrointestinal discomfort.

Serious or Rare Side Effects

  • Fat overload syndrome: severe hyperlipidemia with organ dysfunction.
  • Anaphylactic reaction: sudden severe allergy requiring emergency treatment.
  • Pulmonary embolism: lipid emboli causing respiratory compromise.

Precautions & Warnings

When using Lipofundin Mct/Lct, several precautions should be observed to ensure patient safety.

  • Monitor triglyceride levels: check serum triglycerides regularly during therapy.
  • Assess lipid tolerance: discontinue if signs of intolerance such as fever or respiratory distress appear.
  • Use aseptic technique: maintain sterility of infusion set and catheter.
  • Avoid in known soy or egg phospholipid allergy: contraindicated in patients with hypersensitivity.
  • Adjust dose in hepatic impairment: reduce infusion rate in patients with liver dysfunction.
  • Store at 2-8°C: keep refrigerated, protect from light, do not freeze or shake.

Avoid Interactions

Lipofundin Mct/Lct can interact with certain medications, affecting lipid levels or infusion safety.

Major Interactions (Avoid)

  • Co‑administration with other lipid emulsions: risk of severe hypertriglyceridemia.
  • Concurrent propofol infusion: additive lipid load may cause fat overload.
  • High‑dose heparin therapy: may increase triglyceride concentrations.

Moderate Interactions (Monitor Closely)

  • Corticosteroids: may elevate triglyceride levels, requiring monitoring.
  • Total parenteral nutrition components: electrolyte and vitamin balance should be reviewed.
  • Certain antiretroviral agents (e.g., protease inhibitors): can affect lipid metabolism.

Frequently Asked Questions

Lipofundin Mct/Lct is an intravenous lipid emulsion used as a component of parenteral nutrition. It provides a source of calories and essential fatty acids for patients who cannot receive enteral feeding and helps prevent essential fatty acid deficiency during prolonged intravenous therapy.

The formulation supplies triglycerides that are hydrolyzed by plasma lipases after infusion. The resulting free fatty acids are taken up by cells for energy production via β‑oxidation and for synthesis of phospholipids. Medium‑chain fatty acids are rapidly oxidized, while the long‑chain soybean fatty acids deliver essential linoleic and α‑linolenic acids needed for membrane integrity.

The prescribed dose of Lipofundin Mct/Lct is individualized by the treating clinician based on the patient’s caloric requirements, body weight, metabolic status, and laboratory monitoring of triglyceride levels. No fixed regimen is provided; the prescriber calculates the infusion rate to meet specific nutritional goals.

Safety data for Lipofundin Mct/Lct in pregnancy and lactation are limited, and the product is classified as pregnancy category unknown. Use is generally reserved for situations where the benefit to the mother outweighs potential risks to the fetus or infant, and it should be prescribed only after careful clinical assessment.

To place an order, submit an enquiry on the product page at gnhindia.com indicating the required quantity. GNH India supplies hospitals, pharmacies and procurement teams across international markets. After the request, the sales team will verify trade or institutional credentials, then provide pricing, availability, shipping details (including cold‑chain where applicable) and any necessary import documentation.

Lipofundin Mct/Lct combines soybean oil with medium‑chain triglycerides, offering a balanced profile of long‑chain essential fatty acids and rapidly oxidizable medium‑chain fats. Compared with pure soybean‑oil emulsions, it may result in lower triglyceride accumulation and provides quicker energy availability, while still meeting essential fatty acid requirements.

The emulsion should be stored refrigerated at 2‑8 °C, protected from light, and must not be frozen or shaken. Before use, inspect the container for any signs of separation or discoloration. Keep the product in its original packaging until administration to maintain sterility and stability.

Lipofundin Mct/Lct is administered intravenously as an emulsion infusion, typically via a dedicated lumen or filter set to prevent lipid buildup. The infusion rate is set by the prescriber based on the patient’s nutritional plan and monitored regularly for tolerance and serum triglyceride levels.

Serious risks include fat overload syndrome, which can lead to organ dysfunction, and severe allergic reactions such as anaphylaxis. Rarely, lipid embolism or pulmonary complications may occur. Prompt recognition of symptoms and immediate medical intervention are essential to mitigate these risks.

Patients with known hypersensitivity to soy, egg phospholipids, or any component of the emulsion should not receive Lipofundin Mct/Lct. It is also contraindicated in individuals with severe hypertriglyceridemia, uncontrolled lipid metabolism disorders, or those who have experienced previous severe reactions to intravenous lipid emulsions.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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