Product image of Lipofundin Mct/Lct (Soya-Bean Oil Refined, Triglycerides, Medium Chain) supplied by GNH India

Lipofundin Mct/Lct

Active Ingredient:
Soya-Bean Oil Refined, Triglycerides, Medium Chain
Origin:
EU

Lipofundin Mct/Lct (Soya-Bean Oil Refined, Triglycerides, Medium Chain)

Soybean oil, the active ingredient in Lipofundin Mct/Lct, is a parenteral nutrition lipid emulsion presented as an intravenous lipid emulsion for intravenous use. It supplies calories and essential fatty acids to patients who cannot receive enteral feeding, supporting energy needs and membrane phospholipid synthesis.

GNH India supplies Lipofundin Mct/Lct as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, transplant centres, oncology centres, pharmacies and clinics worldwide, ensuring quality assurance, regulatory compliance and reliable cold‑chain logistics for clinical parenteral nutrition products.

Manufacturer / TM Owner

B.Braun Melsungen Ag

1
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Indications & Clinical Uses

  • Lipofundin Mct/Lct is a parenteral nutrition lipid emulsion used to provide caloric and essential fatty acid support.
  • Enteral feeding intolerance: supplies calories and essential fatty acids when oral or tube feeding is not possible.
  • Post‑operative recovery: provides supplemental energy and fatty acids to support healing after surgery.
  • Critical illness or severe malnutrition: delivers necessary lipids for patients in intensive care or with profound nutritional deficits.

How It Works

  • The emulsion contains long‑chain triglycerides from soybean oil and medium‑chain triglycerides that are hydrolyzed by lipases to free fatty acids and glycerol. These substrates are rapidly oxidized for energy and incorporated into cell membrane phospholipids, thereby supplying calories and essential fatty acids needed for growth, repair, and metabolic functions during parenteral nutrition.

Side Effects

Lipofundin Mct/Lct may cause a range of infusion‑related reactions.

Common Side Effects

  • Hypertriglyceridaemia: elevated serum triglyceride levels.
  • Fever or chills during infusion.
  • Infusion site erythema or pain.
  • Nausea or mild gastrointestinal discomfort.
  • Headache.
  • Transient increase in liver enzymes.

Serious or Rare Side Effects

  • Fat overload syndrome: respiratory distress, hepatomegaly, coagulopathy.
  • Anaphylactic or severe allergic reaction.
  • Pulmonary embolism from lipid particles.
  • Severe hepatic dysfunction or steatosis.
  • Thrombocytopenia.
  • Increased risk of infection due to lipid‑rich medium.

Precautions & Warnings

  • When using Lipofundin Mct/Lct, clinicians should follow key safety measures.
  • Assess triglyceride levels: monitor serum triglycerides before and during therapy.
  • Check for allergies: avoid in patients with known soybean or egg allergy.
  • Use aseptic technique: ensure sterile handling to prevent contamination.
  • Monitor for signs of fat overload: watch for respiratory distress, fever, hepatomegaly.
  • Avoid concomitant lipid‑containing infusions: prevent excess lipid load.
  • Store at 2-8°C: keep refrigerated, protect from light, do not freeze or shake.

Avoid Interactions

Lipofundin Mct/Lct can interact with several medications affecting lipid metabolism.

Major Interactions (Avoid)

  • Propofol: additive lipid load may cause severe hypertriglyceridaemia.
  • Corticosteroids: increase serum triglyceride concentrations.
  • Heparin: may potentiate hypertriglyceridaemia.

Moderate Interactions (Monitor Closely)

  • Cyclosporine: may raise lipid levels.
  • Estrogen therapy: can elevate triglycerides.
  • Concurrent parenteral nutrition containing other lipids: risk of excess calories and lipid overload.

Frequently Asked Questions

Lipofundin Mct/Lct is an intravenous lipid emulsion used as part of parenteral nutrition. It provides calories and essential fatty acids to patients who cannot receive enteral feeding, such as those in intensive care, post‑operative recovery, or with severe malnutrition.

Soybean oil supplies long‑chain triglycerides that are hydrolyzed to free fatty acids and glycerol. These are rapidly oxidized for energy and incorporated into cell membranes, delivering essential fatty acids required for cellular function and tissue repair during intravenous nutrition.

The prescribed dose is individualized by the treating clinician based on the patient’s caloric requirements, weight, metabolic status, and serum triglyceride levels. No fixed regimen is provided; dosing is adjusted to meet specific nutritional goals.

Safety data in pregnancy and lactation are limited. Use is generally reserved for situations where the nutritional benefit outweighs potential risks, and the decision should be made by the prescribing physician after careful assessment.

Submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including cold‑chain where required) and import documentation.

Lipofundin Mct/Lct combines soybean oil (long‑chain) with medium‑chain triglycerides, offering a balanced fatty‑acid profile and faster oxidation of MCTs. Compared with pure soybean‑oil emulsions, it may result in lower serum triglyceride spikes and provides additional energy from MCTs, which can be advantageous in critically ill patients.

The emulsion must be stored refrigerated at 2‑8 °C, protected from light, and should never be frozen or shaken. Keep the container in its original packaging until use to maintain sterility and product integrity.

It is administered intravenously, typically as a continuous infusion or intermittent infusion mixed with compatible parenteral nutrition solutions. Administration set‑up follows aseptic technique, and infusion rates are adjusted according to the prescribed caloric and lipid goals.

Serious adverse events include fat overload syndrome, severe hypertriglyceridaemia, anaphylactic reactions, pulmonary embolism from lipid particles, and significant hepatic dysfunction. Early detection of respiratory distress, unexplained fever, or rapid rise in triglyceride levels is essential.

Patients with known hypersensitivity to soybean oil, egg phospholipids, or any component of the emulsion should avoid it. It is also contraindicated in individuals with severe hypertriglyceridaemia, uncontrolled sepsis, or those receiving incompatible lipid‑containing infusions that could cause excess lipid load.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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