Product image of Lipofundina Mct/Lct (Soya-Bean Oil Refined, Triglycerides, Medium Chain) supplied by GNH India

Lipofundina Mct/Lct

Active Ingredient:
Soya-Bean Oil Refined, Triglycerides, Medium Chain
Origin:
EU

Lipofundina Mct/Lct (Soya-Bean Oil Refined, Triglycerides, Medium Chain)

Soya-Bean Oil Refined, the active ingredient in Lipofundina MCT/LCT, is a parenteral lipid emulsion presented as an intravenous solution for use in patients requiring nutritional support. It provides calories and essential fatty acids for individuals who cannot receive enteral feeding.

GNH India supplies Lipofundina MCT/LCT as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, transplant centres, oncology centres, pharmacies and clinics worldwide.

Manufacturer / TM Owner

B.Braun Medical, S.A.

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Indications & Clinical Uses

Lipofundina MCT/LCT is used as an intravenous lipid emulsion in total parenteral nutrition to supply energy and essential fatty acids.

  • Total parenteral nutrition (TPN): provides caloric density and essential fatty acids for patients unable to receive enteral feeding.
  • Prevention of essential fatty acid deficiency: supplies linoleic and alpha‑linolenic acids during long‑term parenteral therapy.
  • Support in postoperative or trauma care: delivers rapid energy to patients with increased metabolic demand.

How It Works

  • Lipofundina MCT/LCT delivers a mixture of medium‑chain and long‑chain triglycerides that are hydrolyzed by lipoprotein lipase after intravenous infusion. The resulting free fatty acids are taken up by tissues for beta‑oxidation, providing a dense source of calories, while the fatty acid profile supplies essential linoleic and alpha‑linolenic acids required for cell membrane synthesis and physiological functions.

Side Effects

Lipofundina MCT/LCT may be associated with a range of infusion‑related reactions.

Common Side Effects

  • Hypertriglyceridaemia: elevated serum triglyceride levels.
  • Fever or chills during infusion.
  • Infusion site pain or erythema.
  • Nausea or vomiting.
  • Headache.
  • Mild respiratory discomfort.

Serious or Rare Side Effects

  • Fat overload syndrome: severe hyperlipidaemia with organ dysfunction.
  • Acute pancreatitis.
  • Anaphylactic or severe allergic reactions.
  • Hepatic dysfunction or cholestasis.
  • Pulmonary embolism from lipid droplets.
  • Sepsis related to contaminated product.

Precautions & Warnings

When using Lipofundina MCT/LCT, clinicians should observe several safety measures.

  • Monitor triglyceride levels: check serum triglycerides regularly during therapy.
  • Assess liver function: watch for hepatic enzyme elevations.
  • Evaluate for fat metabolism disorders: avoid in patients with severe hyperlipidaemia or known lipid metabolism defects.
  • Check for soy or egg allergy: contraindicated in individuals with hypersensitivity to soy‑derived products.
  • Use aseptic technique: prevent microbial contamination during preparation and administration.
  • Store at 2-8°C: keep refrigerated, protect from light, do not freeze or shake.

Avoid Interactions

Lipofundina MCT/LCT can interact with other agents that affect lipid metabolism or share a lipid carrier.

Major Interactions (Avoid)

  • Concomitant lipid emulsions (e.g., propofol): risk of cumulative fat load and severe hypertriglyceridaemia.
  • Heparin therapy: may increase lipoprotein lipase activity, altering triglyceride clearance.

Moderate Interactions (Monitor Closely)

  • Fibrates or statins: potential additive effect on serum lipid levels.
  • High‑dose glucose infusions: may exacerbate hypertriglyceridaemia.
  • Immunosuppressants (e.g., cyclosporine): monitor liver function as both can affect hepatic metabolism.
  • Vitamin E supplementation: may mask oxidative stress signs.
  • Anticoagulants: monitor coagulation parameters as lipid emulsions can affect platelet function.

Frequently Asked Questions

Lipofundina MCT/LCT is an intravenous lipid emulsion used as part of total parenteral nutrition to provide calories and essential fatty acids for patients who cannot receive enteral feeding, such as those in intensive care, postoperative recovery, or with severe malnutrition.

The refined soy‑bean oil supplies a blend of medium‑chain and long‑chain triglycerides. After infusion, lipases hydrolyze these triglycerides into free fatty acids, which are then oxidized for energy and incorporated into cell membranes, delivering both caloric support and essential fatty acids.

The dose of Lipofundina MCT/LCT is individualized. The prescribing clinician determines the volume and rate based on the patient’s caloric needs, lipid requirements, and clinical condition, following established parenteral nutrition protocols.

Safety data for Lipofundina MCT/LCT in pregnancy and lactation are limited. It should only be used if the potential benefit justifies any potential risk to the fetus or infant, and the decision must be made by the treating physician.

To order, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including cold‑chain where required) and import documentation.

Lipofundina MCT/LCT combines medium‑chain and long‑chain triglycerides, offering a balanced energy source and essential fatty acids. Compared with pure long‑chain emulsions, it may provide faster oxidation of medium‑chain fats and a lower risk of essential fatty acid deficiency, while still delivering comparable caloric density.

The product must be stored at 2‑8 °C, protected from light, and should never be frozen or shaken. Before use, inspect the emulsion for discoloration or phase separation and allow it to reach room temperature if required by the administration protocol.

Lipofundina MCT/LCT is administered intravenously, typically via a dedicated infusion line. The infusion rate is set according to the patient’s prescribed lipid calories, and the solution is mixed with other parenteral nutrition components as directed by the clinical nutrition team.

Serious risks include fat overload syndrome, acute pancreatitis, severe allergic reactions (including anaphylaxis), and hepatic dysfunction. Monitoring triglyceride levels, liver function tests, and observing for signs of hypersensitivity are essential to mitigate these risks.

Patients with known hypersensitivity to soy‑bean oil or egg proteins, those with severe hypertriglyceridaemia, disorders of fat metabolism, or uncontrolled sepsis should not receive Lipofundina MCT/LCT. Contra‑indications must be confirmed by the treating physician.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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