Product image of Lipoplus (Omega-3-Acid Triglycerides, Soya-Bean Oil Refined, Triglycerides, Medium Chain) supplied by GNH India

Lipoplus

Active Ingredient:
Omega-3-Acid Triglycerides, Soya-Bean Oil Refined, Triglycerides, Medium Chain
Origin:
EU

Lipoplus (Omega-3-Acid Triglycerides, Soya-Bean Oil Refined, Triglycerides, Medium Chain)

Omega-3-acid triglycerides, the active ingredient in Lipoplus, is a intravenous lipid emulsion presented as an intravenous formulation for intravenous use. It supplies calories and essential fatty acids to patients requiring parenteral nutrition, such as those unable to receive enteral feeding.

GNH India supplies Lipoplus as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, transplant centres and intensive care units worldwide. The company ensures quality compliance with EU standards and provides logistics support for global distribution.

Manufacturer / TM Owner

B.Braun Melsungen Ag

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Indications & Clinical Uses

  • Lipoplus is used in clinical settings to address nutritional and metabolic needs associated with parenteral nutrition.
  • Parenteral nutrition: provides a concentrated source of calories and essential fatty acids for patients receiving total parenteral nutrition.
  • Essential fatty acid deficiency: corrects deficiency in patients lacking enteral intake of omega‑3 and omega‑6 fatty acids.
  • Critical care energy support: serves as an energy source for critically ill patients who cannot tolerate enteral feeding.

How It Works

  • Lipoplus delivers a mixture of omega‑3‑acid triglycerides, refined soybean oil and medium‑chain triglycerides directly into the bloodstream. The lipids are hydrolyzed by lipoprotein lipase, releasing free fatty acids that are oxidized for energy and incorporated into cell membranes, thereby supplying calories and essential fatty acids required for normal cellular function and metabolic processes.

Side Effects

Lipoplus may be associated with a range of infusion‑related adverse reactions.

Common Side Effects

  • Hypertriglyceridemia: elevated blood triglyceride levels.
  • Fever: transient rise in body temperature during infusion.
  • Mild hypotension: temporary drop in blood pressure.
  • Fat overload syndrome: accumulation of fat in the reticuloendothelial system.

Serious or Rare Side Effects

  • Anaphylactic reaction: severe allergic response requiring immediate medical intervention.
  • Liver dysfunction: marked elevation of hepatic enzymes.
  • Coagulopathy: impaired blood clotting due to lipid interference.
  • Pulmonary embolism: rare blockage of pulmonary vessels.

Precautions & Warnings

  • When using Lipoplus, clinicians should observe several safety measures.
  • Patient selection: assess baseline triglyceride levels and liver function before initiating therapy.
  • Infusion rate: administer at recommended rate to reduce risk of fat overload.
  • Monitoring: regularly check serum triglycerides, liver enzymes, and coagulation parameters.
  • Allergy assessment: verify no known hypersensitivity to soy or fish oils.
  • Compatibility: avoid mixing with incompatible intravenous solutions.
  • Store at 2-8°C: keep refrigerated, protect from light, do not freeze or shake.

Avoid Interactions

Lipoplus can interact with other medications and nutritional products; awareness of these interactions helps maintain patient safety.

Major Interactions (Avoid)

  • Heparin therapy: may exacerbate hypertriglyceridemia.
  • Cytotoxic chemotherapy: increased risk of lipid‑related organ toxicity.
  • High‑dose vitamin E supplements: potential for excessive antioxidant effect.

Moderate Interactions (Monitor Closely)

  • Warfarin: lipid emulsion can alter INR values, requiring monitoring.
  • Propofol infusion: additive lipid load may raise triglyceride levels.
  • Total parenteral nutrition containing other lipid sources: risk of cumulative fat overload.

Frequently Asked Questions

Lipoplus is an intravenous lipid emulsion used as a component of total parenteral nutrition. It provides a concentrated source of calories and essential fatty acids for patients who cannot receive nutrition through the gastrointestinal tract, such as those in intensive care, post‑surgical recovery, or with severe gastrointestinal disorders.

The omega‑3‑acid triglycerides in Lipoplus are hydrolyzed by lipoprotein lipase after infusion, releasing free fatty acids that are oxidized for energy and incorporated into cell membranes. This process supplies both caloric energy and essential fatty acids needed for membrane synthesis, inflammatory modulation, and overall metabolic support.

The dose of Lipoplus is individualized by the prescribing clinician based on the patient’s caloric needs, weight, and clinical condition. Dosing calculations consider total energy requirements, existing lipid intake, and laboratory parameters such as triglyceride levels.

Safety data for Lipoplus in pregnancy and lactation are limited. It should only be used if the potential benefit to the mother outweighs any possible risk to the fetus or infant, and the decision must be made by the treating physician in consultation with obstetric specialists.

To order Lipoplus, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including cold‑chain handling if needed) and any required import documentation.

Lipoplus distinguishes itself by combining omega‑3‑acid triglycerides, refined soybean oil and medium‑chain triglycerides, offering a balanced profile of omega‑3, omega‑6 and medium‑chain fatty acids. Compared with emulsions based solely on soybean or olive oil, Lipoplus may provide additional anti‑inflammatory benefits and a broader range of fatty acids for membrane synthesis.

Lipoplus must be stored at 2‑8 °C in a refrigerator. Keep the container in its original packaging, protect it from light, and avoid freezing or shaking the emulsion. Before use, allow the product to reach room temperature if required by the administration protocol.

Lipoplus is administered intravenously, typically as part of a total parenteral nutrition regimen. It is infused through a dedicated lumen or a compatible IV line, following the infusion rate recommended by the prescribing clinician to minimize the risk of fat overload and related complications.

Serious risks include anaphylactic reactions, severe hypertriglyceridemia leading to pancreatitis, liver dysfunction with marked enzyme elevation, coagulopathy, and rare events such as pulmonary embolism. Continuous monitoring of vital signs, triglyceride levels, liver function tests and coagulation parameters is essential during therapy.

Lipoplus should be avoided in patients with known hypersensitivity to any of its components (soybean oil, fish oil, or medium‑chain triglycerides), uncontrolled hypertriglyceridemia, severe liver disease, or in those for whom a lipid‑free parenteral nutrition regimen is clinically indicated.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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