Product image of Lipoplus (Omega-3-Acid Triglycerides, Soya-Bean Oil Refined, Triglycerides, Medium Chain) supplied by GNH India

Lipoplus

Active Ingredient:
Omega-3-Acid Triglycerides, Soya-Bean Oil Refined, Triglycerides, Medium Chain
Origin:
EU

Lipoplus (Omega-3-Acid Triglycerides, Soya-Bean Oil Refined, Triglycerides, Medium Chain)

Omega-3-Acid Triglycerides, the active ingredient in Lipoplus, is a intravenous lipid emulsion presented as a sterile intravenous solution for intravenous use. It provides essential fatty acids and calories to patients who require parenteral nutrition or supplementation of essential fatty acids.

GNH India supplies Lipoplus as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals worldwide.

Manufacturer / TM Owner

B.Braun Melsungen Ag

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Indications & Clinical Uses

Lipoplus is used in clinical settings that require intravenous delivery of essential fatty acids and caloric support.

  • Parenteral nutrition: supplies calories and essential fatty acids for patients unable to receive enteral feeding.
  • Essential fatty acid deficiency: corrects deficiency in patients on long‑term lipid‑restricted diets.
  • Critical care nutrition: supports energy needs of critically ill or post‑surgical patients receiving total parenteral nutrition.

How It Works

  • Lipoplus delivers omega‑3‑acid triglycerides that are hydrolyzed by lipoprotein lipase into free fatty acids, which are then taken up by cells for membrane phospholipid synthesis, energy production, and modulation of inflammatory pathways, thereby supplying essential fatty acids and caloric density during parenteral nutrition.

Side Effects

Lipoplus may be associated with a range of infusion‑related reactions.

Common Side Effects

  • Hypertriglyceridaemia: elevated serum triglyceride levels.
  • Fever or chills during infusion.
  • Infusion site erythema or pain.
  • Mild thrombocytopenia.
  • Transient increase in liver enzymes.
  • Fat overload syndrome in prolonged high‑dose use.

Serious or Rare Side Effects

  • Anaphylactic or severe allergic reactions, especially in patients with soy or fish oil sensitivity.
  • Acute pancreatitis.
  • Severe hepatic dysfunction or steatosis.
  • Pulmonary complications such as fat embolism.
  • Coagulopathy due to lipid‑induced platelet dysfunction.
  • Sepsis related to contaminated infusion sets.

Precautions & Warnings

When using Lipoplus, clinicians should observe several safety measures.

  • Assess triglyceride levels: monitor serum triglycerides regularly during therapy.
  • Monitor liver function: watch for hepatic steatosis or enzyme elevation.
  • Check for allergy: screen patients for known soy or fish oil hypersensitivity.
  • Use aseptic technique: ensure sterile preparation and administration.
  • Avoid in patients with severe hyperlipidaemia: contraindicated due to risk of fat overload.
  • Store at 2-8°C: keep refrigerated, protect from light, do not freeze or shake.

Avoid Interactions

Lipoplus can interact with other therapies that affect lipid metabolism or increase lipid load.

Major Interactions (Avoid)

  • Co‑administration with other intravenous lipid emulsions: cumulative lipid load may cause fat overload syndrome.
  • High‑dose propofol infusion: both provide lipids, increasing risk of hypertriglyceridaemia.

Moderate Interactions (Monitor Closely)

  • Systemic corticosteroids: may elevate serum triglycerides, requiring monitoring.
  • Heparin therapy: can release lipoprotein lipase, altering lipid metabolism.
  • Certain chemotherapeutic agents (e.g., cyclophosphamide): may increase hepatic stress when combined.

Frequently Asked Questions

Lipoplus is an intravenous lipid emulsion that provides calories and essential fatty acids to patients who cannot receive enteral nutrition. It is commonly used as part of total parenteral nutrition, to correct essential fatty acid deficiency, and to support the nutritional needs of critically ill or post‑surgical patients.

The omega‑3‑acid triglycerides in Lipoplus are hydrolysed by lipoprotein lipase into free fatty acids after infusion. These fatty acids are incorporated into cell membranes, serve as an energy source, and modulate inflammatory pathways, thereby supplying essential fatty acids and caloric support during parenteral nutrition.

The dose of Lipoplus is individualized by the prescribing clinician based on the patient’s caloric requirements, lipid tolerance, and clinical condition. Dosing calculations consider factors such as body weight, total parenteral nutrition goals, and serum triglyceride levels.

The safety of Lipoplus in pregnancy or lactation has not been definitively established. It should only be used if the potential benefit to the mother outweighs any possible risk to the fetus or infant, and the decision should be made by the treating physician.

To order Lipoplus, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including cold‑chain if needed), and import documentation.

Lipoplus contains a blend of omega‑3‑acid triglycerides, refined soybean oil, and medium‑chain triglycerides, offering a balanced fatty‑acid profile that may reduce inflammation compared with traditional soybean‑only emulsions. Its composition can provide comparable caloric density while potentially improving lipid tolerance in certain patients.

Lipoplus must be stored refrigerated at 2‑8 °C, protected from light, and must not be frozen or shaken. Before use, inspect the container for any signs of leakage or discoloration and allow the solution to reach room temperature if required by the administration protocol.

Lipoplus is administered intravenously, typically as part of a total parenteral nutrition regimen. It is infused through a sterile infusion set using aseptic technique, and the infusion rate is adjusted according to the prescribed lipid dose and the patient’s tolerance.

Serious risks include severe allergic reactions (anaphylaxis), fat overload syndrome, acute pancreatitis, significant hepatic dysfunction, and pulmonary complications such as fat embolism. Monitoring of triglyceride levels, liver function, and clinical signs of intolerance is essential during therapy.

Lipoplus is contraindicated in patients with known hypersensitivity to any component (including soy or fish oil), those with severe hyperlipidaemia, or individuals with disorders that predispose to fat overload syndrome. Clinicians should evaluate each patient’s medical history before initiating therapy.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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