Product image of Liposic (Carbomer) supplied by GNH India

Liposic

Active Ingredient:
Carbomer
Origin:
EU

Liposic (Carbomer)

Carbomer, the active ingredient in Liposic, is a pharmaceutical excipient presented as a gel-forming agent for ocular use. It functions as a viscosity enhancer in eye preparations, improving drug residence time on the ocular surface.
GNH India supplies Liposic as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, transplant centres, oncology centres, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Bausch + Lomb Ireland Limited

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Indications & Clinical Uses

  • Liposic, containing carbomer, is used as a viscosity enhancer in ophthalmic formulations.
  • Dry eye syndrome: improves tear film stability and prolongs ocular surface lubrication.
  • Post‑operative ocular inflammation: provides sustained delivery of anti‑inflammatory agents.
  • Allergic conjunctivitis: enhances residence time of antihistamine eye drops.
  • Keratitis: supports prolonged contact of antimicrobial eye drops.
  • Glaucoma therapy: aids in controlled release of intra‑ocular pressure‑lowering agents.

How It Works

  • Carbomer is a high‑molecular‑weight cross‑linked polyacrylic acid polymer that swells in aqueous media, forming a three‑dimensional network. This network increases the viscosity of the solution, creating a gel matrix that traps water and active pharmaceutical ingredients, thereby extending their contact time with ocular tissues and enhancing drug absorption.

Side Effects

Carbomer‑based ophthalmic gels are generally well tolerated, but ocular irritation can occur.

Common Side Effects

  • Transient blurred vision: temporary reduction in visual acuity after instillation.
  • Ocular irritation: mild burning or stinging sensation.
  • Foreign body sensation: feeling of something in the eye.
  • Mild conjunctival redness: slight redness without discharge.
  • Excessive tearing: increased lacrimation.
  • Temporary visual haze: brief cloudiness of vision.

Serious or Rare Side Effects

  • Allergic contact dermatitis: localized swelling, itching, or rash.
  • Corneal ulceration: rare development of corneal lesions.
  • Severe eye pain: intense discomfort requiring medical evaluation.
  • Vision loss: extremely rare, sudden loss of sight.
  • Persistent inflammation: ongoing ocular inflammation beyond expected duration.
  • Endophthalmitis: rare intra‑ocular infection.

Precautions & Warnings

  • When using Liposic, consider the following safety measures.
  • Patient counseling: advise that the product is an excipient and may cause temporary visual changes.
  • Allergy screening: avoid use in patients with known carbomer hypersensitivity.
  • Monitor irritation: observe for signs of ocular discomfort or redness.
  • Compatibility testing: do not combine with other ophthalmic gels without confirming stability.
  • Store at room temperature: keep in the original container, protect from moisture and direct sunlight.

Avoid Interactions

Carbomer may interact with other ophthalmic products, affecting formulation stability.

Major Interactions (Avoid)

  • Co‑administration with other gel‑forming agents: may result in excessive viscosity.
  • Incompatible preservatives: certain preservatives can destabilize the carbomer gel matrix.
  • High‑ionic strength solutions: can cause gel breakdown.

Moderate Interactions (Monitor Closely)

  • Contact lens wear: may reduce drug absorption from the gel.
  • Concurrent ocular antibiotics: may alter release profile of the active drug.

Frequently Asked Questions

Liposic is an ophthalmic gel that contains carbomer, a viscosity‑enhancing excipient. It is incorporated into eye drops and suspensions to increase the thickness of the formulation, prolonging the contact time of the active drug on the ocular surface and improving therapeutic efficacy.

Carbomer is a cross‑linked polyacrylic acid polymer that absorbs water and forms a gel matrix. This matrix raises the viscosity of the ophthalmic preparation, creating a thicker layer on the eye that slows drainage and allows the active ingredient to remain in contact with the eye longer.

The dose of Liposic is determined by the prescribing clinician based on the specific ophthalmic product in which it is formulated. The prescriber decides the appropriate volume and frequency of administration for each patient, taking into account the therapeutic indication and the accompanying active drug.

Carbomer is generally considered to have low systemic absorption when applied to the eye. However, safety data specific to pregnancy and lactation are limited. Healthcare professionals should evaluate the risk‑benefit profile for each patient and may choose to avoid use if safer alternatives are available.

To place an order, submit an enquiry on the Liposic product page at gnhindia.com, specifying the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide. After submission, the sales team will verify trade or institutional credentials and respond with pricing, availability, shipping details and any required import documentation.

Carbomer offers a high degree of viscosity control and clear gel formation, which many alternatives such as hyaluronic acid or methylcellulose may not provide. It is chemically stable, compatible with a wide range of active ingredients, and does not typically interfere with drug efficacy, making it a preferred choice for many ophthalmic formulations.

Liposic should be stored at room temperature, below 25 °C, in its original packaging. Protect the product from moisture, direct sunlight and extreme temperature fluctuations. Ensure the container is tightly sealed to maintain gel integrity and prevent contamination.

Liposic is administered as part of an ophthalmic preparation. The clinician or patient instills the prescribed number of drops onto the conjunctival sac, typically using a sterile dropper. The gel’s increased viscosity helps keep the medication in place, reducing the need for frequent dosing.

Serious risks, though rare, include allergic contact dermatitis, corneal ulceration, severe eye pain, and vision loss. Patients should be instructed to seek immediate medical attention if they experience persistent redness, pain, decreased vision, or any signs of an allergic reaction after using the product.

Individuals with a known hypersensitivity to carbomer or any component of the formulation should avoid Liposic. Additionally, patients with active corneal infections or severe ocular surface disease should consult an eye care professional before using products containing carbomer.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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