Product image of Lipovir (Aciclovir) supplied by GNH India

Lipovir

Active Ingredient:
Aciclovir
Origin:
EU

Lipovir (Aciclovir)

Aciclovir, the active ingredient in Lipovir, is a nucleoside analogue antiviral presented as an unspecified strength/topical cream for topical use. It treats herpes labialis and other herpes simplex skin infections in adults.

GNH India supplies Lipovir as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Laboratorios Ojer Pharma, S.L

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Indications & Clinical Uses

  • Aciclovir acts on herpes simplex viruses that cause skin and mucosal lesions.
  • Herpes labialis: reduces the duration and severity of cold sore outbreaks.
  • Herpes simplex skin infections: promotes healing of vesicular lesions caused by HSV‑1 or HSV‑2.
  • Herpes simplex keratitis (topical adjunct): assists in managing ocular surface lesions when used under specialist supervision.

How It Works

  • After topical application, aciclovir is phosphorylated by viral thymidine kinase to aciclovir monophosphate, then further converted to aciclovir triphosphate by cellular kinases. The triphosphate form competitively inhibits viral DNA polymerase, leading to premature termination of viral DNA chain elongation and suppression of viral replication.

Side Effects

Aciclovir topical preparations are generally well tolerated, but local reactions can occur.

Common Side Effects

  • Local irritation: mild burning or stinging at the application site.
  • Redness: transient erythema around the treated area.
  • Itching: occasional pruritus during early use.

Serious or Rare Side Effects

  • Allergic contact dermatitis: rash, swelling, or blistering requiring medical attention.
  • Severe skin reaction: Stevens‑Johnson syndrome or toxic epidermal necrolysis, extremely rare.
  • Systemic absorption leading to nephrotoxicity: reported only with extensive use over large body surface areas.

Precautions & Warnings

  • Before using Lipovir, consider the following safety measures.
  • Pregnancy: consult a healthcare professional; safety data are limited.
  • Breastfeeding: discuss potential risks with a clinician.
  • Open wounds: avoid application on extensive broken skin.
  • Concurrent ocular use: do not apply near eyes unless directed by a specialist.
  • Store at ambient temperature: keep below 25°C, in the original packaging, protected from moisture and direct sunlight.

Avoid Interactions

Aciclovir topical may interact with other agents applied to the same area.

Major Interactions (Avoid)

  • Other topical antivirals: may increase local irritation.
  • Topical corticosteroids: can mask signs of infection and delay healing.

Moderate Interactions (Monitor Closely)

  • Dermatologic agents containing alcohol: may enhance burning sensation.
  • Occlusive dressings: can increase systemic absorption, especially on large areas.
  • Renal impairment: systemic exposure may rise if applied extensively; monitor renal function.

Frequently Asked Questions

Lipovir is a topical formulation containing aciclovir, used to treat herpes labialis (cold sores) and other herpes simplex skin infections by reducing lesion severity and accelerating healing.

Aciclovir is converted by viral enzymes into a triphosphate that blocks viral DNA polymerase, preventing viral DNA synthesis and halting replication of herpes simplex viruses at the site of application.

The dosing regimen for Lipovir is determined by the prescribing healthcare professional based on the infection’s location, severity, and patient factors. Patients should follow the specific instructions provided by their clinician.

Safety data for topical aciclovir in pregnancy and lactation are limited. Women who are pregnant, planning pregnancy, or breastfeeding should discuss potential risks and benefits with their healthcare provider before using Lipovir.

To order Lipovir, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Lipovir’s active ingredient, aciclovir, is a nucleoside analogue antiviral that directly inhibits viral DNA polymerase. Compared with non‑nucleoside topical agents, aciclovir offers a well‑established efficacy profile for herpes simplex lesions and is widely accepted as first‑line therapy.

Store Lipovir at ambient temperature, below 25 °C. Keep the tube tightly closed, in its original packaging, and protect it from moisture, direct sunlight and extreme temperatures to maintain product stability.

Apply a thin layer of Lipovir to the affected skin area, typically five times daily for the first few days, then reduce frequency as directed by a healthcare professional. Wash hands before and after application to avoid accidental contact with eyes or mucous membranes.

Serious risks, though rare, include allergic contact dermatitis, severe skin reactions such as Stevens‑Johnson syndrome, and systemic toxicity if applied over large body surfaces or on compromised skin. Immediate medical attention is required if these symptoms develop.

Lipovir should not be used by individuals with known hypersensitivity to aciclovir or any excipients in the formulation, and it is contraindicated on extensive broken skin or in patients with severe renal impairment without medical supervision.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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