Loxicom

Active Ingredient:: Meloxicam
Brand:: Loxicom
Origin:: European Union

Loxicom (Meloxicam)

Meloxicam, the active ingredient in Loxicom, is a non‑steroidal anti‑inflammatory drug (NSAID) presented as an oral tablet for systemic use. It is indicated for pain and inflammation associated with osteoarthritis, musculoskeletal conditions, and post‑operative recovery.
GNH India supplies Loxicom as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

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Indications & Clinical Uses

Loxicom (meloxicam) is used to manage inflammatory pain conditions by inhibiting prostaglandin synthesis.

Osteoarthritis: reduces joint pain and improves mobility in patients with degenerative joint disease.
Musculoskeletal pain: alleviates pain and inflammation in muscles, tendons, and ligaments.
Post‑operative pain: provides analgesia after surgical procedures to enhance recovery.

How It Works

Meloxicam selectively inhibits the cyclooxygenase‑2 (COX‑2) enzyme, which reduces the conversion of arachidonic acid to prostaglandins. Lower prostaglandin levels diminish inflammation, pain, and fever while sparing COX‑1 activity, helping to maintain gastric mucosal protection.

Side Effects

Adverse reactions may occur with meloxicam therapy.

Common Side Effects

Gastrointestinal discomfort: nausea, dyspepsia, or abdominal pain.
Headache: mild to moderate intensity.
Dizziness or vertigo.
Edema: peripheral swelling, especially in the lower limbs.
Elevated liver enzymes: transient increases in hepatic transaminases.
Skin rash: mild erythema or pruritus.

Serious or Rare Side Effects

Gastrointestinal ulceration or bleeding.
Severe hepatic injury or jaundice.
Renal impairment or acute kidney injury.
Cardiovascular events such as myocardial infarction or stroke.
Anaphylactic reactions: hives, swelling, or respiratory distress.
Blood dyscrasias: thrombocytopenia or leukopenia.

Precautions & Warnings

Before initiating meloxicam therapy, consider the following safety measures.

Renal function: assess baseline kidney function and monitor periodically.
Hepatic health: evaluate liver enzymes before treatment and during therapy.
Cardiovascular risk: use cautiously in patients with history of heart disease or stroke.
Gastrointestinal history: avoid in individuals with active ulcers or severe GI bleeding.
Pregnancy and lactation: contraindicated unless clearly needed; discuss risks with a healthcare professional.
Store at ambient temperature: keep below 25 °C, retain in original packaging, protect from moisture and direct sunlight.

Avoid Interactions

Meloxicam may interact with several drug classes, requiring careful management.

Major Interactions (Avoid)

Anticoagulants (e.g., warfarin): increased risk of serious bleeding.
Other NSAIDs or COX‑2 inhibitors: heightened gastrointestinal toxicity.
High‑dose aspirin: additive effects on platelet function and bleeding.

Moderate Interactions (Monitor Closely)

ACE inhibitors or ARBs: potential reduction in renal function.
Diuretics: may exacerbate renal impairment.
Lithium: possible increase in lithium serum levels.
Methotrexate: reduced clearance leading to toxicity.

Frequently Asked Questions

Loxicom, containing meloxicam, is prescribed to relieve pain and inflammation caused by osteoarthritis, musculoskeletal disorders such as tendonitis or bursitis, and to manage post‑operative pain after surgical procedures.

Meloxicam selectively blocks the COX‑2 enzyme, which lowers the production of prostaglandins—chemicals that trigger inflammation, pain, and fever. By reducing prostaglandin levels, meloxicam diminishes these symptoms while sparing COX‑1 activity that protects the stomach lining.

The dosage of Loxicom is determined by the prescribing clinician based on the patient’s condition, age, weight, and renal or hepatic function. Only a qualified healthcare professional should set the appropriate dose.

Meloxicam is generally avoided during pregnancy, especially in the third trimester, because it may affect fetal cardiovascular development. It is also excreted in breast milk; therefore, use while breastfeeding should only occur if the benefits outweigh potential risks and under medical supervision.

To place an order, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details, and any necessary import documentation.

Loxicom (meloxicam) offers a longer half‑life than many traditional NSAIDs, allowing once‑daily dosing for many patients. Its COX‑2 selectivity may reduce gastrointestinal side effects compared with non‑selective NSAIDs, though it still carries cardiovascular and renal risks that require monitoring.

Loxicom tablets should be stored at ambient temperature, below 25 °C, in their original container. Keep them away from moisture, direct sunlight, and excessive heat to maintain product stability.

Loxicom is supplied as oral tablets that are swallowed whole with a glass of water. It is typically taken once daily, with or without food, as directed by the prescribing clinician.

Serious risks include gastrointestinal ulceration or bleeding, severe liver injury, acute kidney failure, cardiovascular events such as heart attack or stroke, and rare but life‑threatening allergic reactions like anaphylaxis. Patients should seek immediate medical attention if they experience symptoms such as severe abdominal pain, dark stools, jaundice, sudden swelling, or difficulty breathing.

Loxicom is contraindicated in individuals with known hypersensitivity to meloxicam or other NSAIDs, active gastrointestinal ulceration or bleeding, severe heart failure, and in the third trimester of pregnancy. It should also be used with caution in patients with impaired renal or hepatic function.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated: 29 Jul 2026

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Loxicom (Meloxicam)

Indications & Clinical Uses

How It Works