Macrogol Balance Ratiopharm (Sodium Hydrogen Carbonate, Potassium Chloride, Sodium Chloride, Macrogol 3350)

Macrogol 3350 is a high‑molecular‑weight polyethylene glycol that is not absorbed from the gastrointestinal tract. It retains water in the intestinal lumen by creating an osmotic gradient, which softens the stool and increases its volume, thereby stimulating peristalsis and facilitating bowel movements.

The dose of Macrogol Balance Ratiopharm is individualized by the prescribing healthcare professional based on the patient’s condition, age, and response. The prescriber determines the appropriate amount of powder to dissolve in water and the frequency of administration.

Safety data for macrogol 3350 during pregnancy and lactation are limited. It should be used only if the potential benefit justifies the potential risk to the fetus or infant, and always under the guidance of a qualified healthcare provider.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements) and necessary import documentation.

Macrogol Balance uses macrogol 3350, an osmotic agent that draws water into the colon without being metabolised, whereas lactulose is a synthetic disaccharide that is fermented by colonic bacteria to produce acids and osmotic pressure. Macrogol generally provides a faster onset, less gas production, and more predictable electrolyte balance compared with lactulose.

Store the product at ambient temperature, preferably below 25 °C. Keep the container tightly closed, protect it from moisture and direct sunlight, and retain it in its original packaging until use to preserve product integrity.

The powder is reconstituted by dissolving the prescribed amount in a measured volume of water, typically 200 ml, and the solution is taken orally. It should be consumed promptly after preparation and may be followed by additional fluid intake as advised by the prescriber.

Serious risks include significant electrolyte disturbances such as hypernatremia or hypokalemia, severe abdominal pain, and rare allergic reactions that may manifest as rash, angioedema, or anaphylaxis. Patients should seek immediate medical attention if any of these symptoms occur.

Macrogol Balance should be avoided in individuals with known or suspected intestinal obstruction, perforation, severe renal impairment, uncontrolled heart failure, or a documented hypersensitivity to macrogol or any of the electrolyte components.