Product image of Macrogol + Electrolytes Eg (Sodium Hydrogen Carbonate, Potassium Chloride, Sodium Chloride, Macrogol 3350) supplied by GNH India

Macrogol + Electrolytes Eg

Active Ingredient:
Sodium Hydrogen Carbonate, Potassium Chloride, Sodium Chloride, Macrogol 3350
Origin:
EU

Macrogol + Electrolytes Eg (Sodium Hydrogen Carbonate, Potassium Chloride, Sodium Chloride, Macrogol 3350)

Macrogol 3350 with electrolytes, the active ingredient in Macrogol + Electrolytes Eg, is an osmotic laxative presented as an oral solution for oral use. It treats constipation and is used for bowel preparation before diagnostic procedures in adults and children as directed by a healthcare professional.

GNH India supplies Macrogol + Electrolytes Eg as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Eurogenerics N.V./S.A.

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Indications & Clinical Uses

Macrogol + Electrolytes Eg is an osmotic laxative used to manage conditions affecting bowel motility and to prepare the colon for examination.

  • Constipation: provides gentle bowel evacuation by increasing stool water content.
  • Bowel preparation for colonoscopy: cleanses the colon to allow clear visualisation during the procedure.
  • Bowel preparation for radiologic imaging: facilitates adequate cleansing of the large intestine before contrast studies.

How It Works

  • Macrogol 3350 creates an osmotic gradient within the intestinal lumen that retains water, thereby increasing stool water content and softening the stool. The accompanying electrolytes (sodium hydrogen carbonate, potassium chloride, sodium chloride) maintain electrolyte balance while promoting intestinal water retention, leading to enhanced peristalsis and bowel evacuation.

Side Effects

Macrogol + Electrolytes Eg may cause a range of adverse reactions, most of which are mild and transient.

Common Side Effects

  • Abdominal bloating: sensation of fullness or swelling in the abdomen.
  • Nausea: mild to moderate feeling of queasiness.
  • Flatulence: increased intestinal gas.
  • Mild abdominal cramps: intermittent discomfort.
  • Diarrhoea: loose stools occurring more frequently.
  • Mild electrolyte imbalance: slight changes in serum sodium or potassium.

Serious or Rare Side Effects

  • Severe dehydration: marked loss of body fluids requiring medical attention.
  • Severe electrolyte disturbances: significant hypernatremia or hypokalemia.
  • Allergic reactions: rash, itching, or angioedema.
  • Severe abdominal pain: intense, persistent pain.
  • Colonic perforation: rare but life‑threatening tear of the colon wall.
  • Anaphylaxis: rare systemic allergic response.

Precautions & Warnings

When prescribing or dispensing Macrogol + Electrolytes Eg, consider the following safety measures.

  • Assess renal function: avoid or adjust use in severe renal impairment.
  • Monitor electrolytes: especially in patients with heart failure or on diuretics.
  • Use with caution in the elderly: increased risk of dehydration.
  • Avoid in complete bowel obstruction: the product requires intestinal transit.
  • Discontinue if severe abdominal pain or vomiting occurs.
  • Store at room temperature: keep in the original container, protect from moisture and heat.

Avoid Interactions

Macrogol + Electrolytes Eg can interact with other medications that affect fluid or electrolyte balance.

Major Interactions (Avoid)

  • Concomitant osmotic laxatives (e.g., lactulose): may cause excessive fluid loss and electrolyte imbalance.
  • Loop diuretics: increased risk of hypokalemia.
  • ACE inhibitors or ARBs: potential for renal dysfunction when combined with electrolyte shifts.

Moderate Interactions (Monitor Closely)

  • Sodium‑containing antacids: may raise sodium load.
  • NSAIDs: may affect renal function, especially in dehydrated patients.
  • Oral rehydration solutions: can alter intended electrolyte composition.
  • Thyroid hormone replacement: absorption may be affected by rapid intestinal transit.
  • Antiepileptic drugs: monitor levels if significant diarrhoea occurs.

Frequently Asked Questions

Macrogol + Electrolytes Eg is an oral osmotic laxative used to relieve constipation and to cleanse the bowel before diagnostic procedures such as colonoscopy or radiologic imaging. It works by increasing the water content of stool, facilitating easier evacuation.

Macrogol 3350 creates an osmotic gradient in the intestinal lumen that draws water into the bowel. The added electrolytes help maintain a balanced electrolyte environment while the increased fluid softens stool and stimulates peristalsis, leading to bowel evacuation.

The dose of Macrogol + Electrolytes Eg is individualized by the prescribing healthcare professional based on the patient’s age, weight, severity of constipation, and the intended bowel‑cleansing procedure. Patients should follow the prescriber’s instructions and not self‑adjust the dose.

Safety data for use in pregnancy or lactation are limited. The product should only be used if the potential benefit justifies any possible risk to the fetus or infant, and this decision must be made by a qualified healthcare provider.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Compared with stimulant laxatives, macrogol‑based products provide a gentler, osmotic mechanism that is less likely to cause cramping. Unlike saline laxatives, the added electrolytes help maintain electrolyte balance, making it suitable for bowel preparation where large fluid shifts are expected.

Store the oral solution at room temperature, below 25 °C. Keep it in the original packaging, protect it from moisture and direct sunlight, and ensure the container is tightly closed to maintain product stability.

The product is taken orally as a liquid solution. It is usually mixed with a specified amount of water or other clear fluid as directed by the prescriber, and consumed over a defined period to achieve the desired bowel‑cleansing effect.

Serious risks include severe dehydration, marked electrolyte disturbances (such as hypernatremia or hypokalemia), allergic reactions, and, rarely, colonic perforation. Patients should seek immediate medical attention if they experience severe abdominal pain, persistent vomiting, or signs of electrolyte imbalance.

The product should be avoided in individuals with complete bowel obstruction, severe renal impairment, known hypersensitivity to any component, or in those who have experienced severe reactions to osmotic laxatives. A healthcare professional should evaluate suitability before use.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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