Product image of Macrogol En Elektrolyten Alpex (Sodium Hydrogen Carbonate, Potassium Chloride, Sodium Chloride, Macrogol 3350) supplied by GNH India

Macrogol En Elektrolyten Alpex

Active Ingredient:
Sodium Hydrogen Carbonate, Potassium Chloride, Sodium Chloride, Macrogol 3350
Origin:
EU

Macrogol En Elektrolyten Alpex (Sodium Hydrogen Carbonate, Potassium Chloride, Sodium Chloride, Macrogol 3350)

Macrogol 3350, the active ingredient in Macrogol En Elektrolyten Alpex, is an osmotic laxative presented as an oral formulation for oral use. It is indicated for relief of constipation and for replacement of electrolytes in patients requiring fluid balance support.
GNH India supplies Macrogol En Elektrolyten Alpex as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Alpex Pharma (Irl) Limited

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

Macrogol En Elektrolyten Alpex is an osmotic laxative and electrolyte replenisher used in the following conditions:

  • Constipation: softens stools and promotes bowel movements in occasional or chronic constipation.
  • Electrolyte depletion: restores sodium, potassium and bicarbonate during conditions such as diarrhoea or bowel preparation.
  • Bowel‑preparation adjunct: maintains electrolyte balance while patients undergo bowel cleansing for diagnostic procedures.

How It Works

  • Macrogol 3350 acts as a high‑molecular‑weight polymer that remains within the intestinal lumen, binding water molecules and creating an osmotic gradient that increases stool water content. The added electrolytes (sodium hydrogen carbonate, potassium chloride, sodium chloride) are absorbed to help preserve systemic fluid and electrolyte homeostasis during the laxative effect.

Side Effects

Macrogol En Elektrolyten Alpex may cause a range of adverse reactions.

Common Side Effects

  • Abdominal bloating: feeling of fullness or swelling in the abdomen.
  • Flatulence: increased intestinal gas.
  • Nausea: mild upset stomach.
  • Mild abdominal cramps: intermittent discomfort.
  • Diarrhoea: loose stools occurring more frequently.
  • Thirst: increased desire to drink fluids.

Serious or Rare Side Effects

  • Severe dehydration: marked loss of body water requiring medical attention.
  • Electrolyte imbalance: abnormal sodium or potassium levels that may affect cardiac or neuromuscular function.
  • Allergic reactions: rash, itching, angioedema, or anaphylaxis.
  • Severe abdominal pain: persistent, intense pain possibly indicating obstruction.
  • Colonic perforation: rare but life‑threatening tear of the colon wall.

Precautions & Warnings

Before using Macrogol En Elektrolyten Alpex, consider the following precautions:

  • Assess renal function: adjust use in patients with impaired kidney function.
  • Monitor electrolyte levels: especially sodium and potassium during prolonged therapy.
  • Avoid in complete bowel obstruction: risk of worsening blockage.
  • Use with caution in elderly: higher susceptibility to dehydration.
  • Pregnancy and lactation: consult a healthcare professional before initiating therapy.
  • Store at room temperature: keep in the original container, protect from moisture.

Avoid Interactions

Macrogol En Elektrolyten Alpex can interact with several medication classes.

Major Interactions (Avoid)

  • Loop diuretics: may exacerbate electrolyte loss.
  • Mineralocorticoid antagonists (e.g., spironolactone): risk of hyperkalaemia.
  • Other osmotic laxatives: additive effect leading to severe diarrhoea.
  • Sodium‑containing medications: potential for hypernatremia.
  • Antacids containing sodium bicarbonate: may alter electrolyte balance.

Moderate Interactions (Monitor Closely)

  • ACE inhibitors: monitor potassium levels.
  • NSAIDs: may affect renal function when combined.
  • Corticosteroids: increased risk of fluid loss.
  • Anticholinergic drugs: may reduce laxative efficacy.
  • Oral rehydration solutions: coordinate electrolyte content to avoid excess.

Frequently Asked Questions

Macrogol En Elektrolyten Alpex is an oral osmotic laxative that also contains electrolytes. It is used to relieve occasional or chronic constipation and to replace lost sodium, potassium and bicarbonate in patients who need fluid‑electrolyte balance, such as during bowel preparation or after diarrhoeal illness.

Macrogol 3350 is a large polymer that stays in the intestinal lumen and binds water, creating an osmotic gradient that draws additional fluid into the bowel. This increases stool water content, softening the stool and promoting peristalsis. The accompanying electrolytes are absorbed to help maintain normal systemic electrolyte concentrations.

The appropriate dose of Macrogol En Elektrolyten Alpex is determined by the prescribing healthcare professional based on the individual’s condition, age, renal function and electrolyte status. Patients should follow the prescriber’s instructions and not adjust the dose without medical advice.

Safety data for Macrogol En Elektrolyten Alpex during pregnancy and lactation are limited. Healthcare providers should weigh the potential benefits against any possible risks and consider alternative therapies when appropriate. Women who are pregnant, planning pregnancy, or breastfeeding should discuss use with their physician.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide. After submission, the sales team will verify trade or institutional credentials and respond with pricing, availability, shipping details (including any cold‑chain requirements) and required import documentation.

Compared with stimulant laxatives, Macrogol En Elektrolyten Alpex works by osmotic water retention rather than stimulating intestinal muscle activity, resulting in a gentler, more physiologic stool softening. Unlike simple saline laxatives, it also provides electrolytes, reducing the risk of electrolyte depletion during prolonged use.

Store the product at room temperature, below 25 °C, in its original packaging to protect it from moisture and light. Keep the container tightly closed when not in use and ensure it is out of reach of children.

The product is taken orally, usually dissolved in a measured amount of water or another suitable liquid as directed by the prescriber. It should be consumed with adequate fluid intake to support its osmotic action and to help maintain hydration.

Serious risks include severe dehydration, significant electrolyte disturbances (such as hypernatremia or hyperkalaemia), allergic reactions ranging from rash to anaphylaxis, and, rarely, colonic perforation. Patients should seek immediate medical attention if they experience extreme weakness, rapid heartbeat, severe abdominal pain, or signs of an allergic response.

The product should be avoided in individuals with complete bowel obstruction, known hypersensitivity to macrogol or any of its electrolytes, and in patients with severe renal impairment where electrolyte handling is compromised. A healthcare professional should evaluate suitability before initiating therapy.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Related Products

Other formulations containing Sodium Hydrogen Carbonate, Potassium Chloride, Sodium Chloride, Macrogol 3350

A

A
A

A
A

A
A

A

Browse all products →

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Regulatory recognitions

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.

SGS GSDP Certification

GSDP Compliant from SGS

URS ISO 9001

URS ISO 9001 Certification

FDA Maharashtra

Licensed by FDA Maharashtra

IEC License DGFT

IEC License issued by DGFT