Product image of Macrogol En Elektrolyten Aurobindo (Sodium Hydrogen Carbonate, Potassium Chloride, Sodium Chloride, Macrogol 3350) supplied by GNH India

Macrogol En Elektrolyten Aurobindo

Active Ingredient:
Sodium Hydrogen Carbonate, Potassium Chloride, Sodium Chloride, Macrogol 3350
Origin:
EU

Macrogol En Elektrolyten Aurobindo (Sodium Hydrogen Carbonate, Potassium Chloride, Sodium Chloride, Macrogol 3350)

Macrogol 3350, the active ingredient in Macrogol En Elektrolyten Aurobindo, is an osmotic laxative presented as an oral solution for oral use. It softens stool and promotes bowel movements, helping to relieve constipation and to prepare the bowel for diagnostic or surgical procedures in adults and children.

GNH India supplies Macrogol En Elektrolyten Aurobindo as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The product meets EU quality standards and is distributed under strict regulatory compliance.

Manufacturer / TM Owner

Aurobindo Pharma B.V.

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Indications & Clinical Uses

Macrogol En Elektrolyten Aurobindo is used as an osmotic laxative to manage conditions affecting bowel transit.

  • Constipation: Relieves infrequent or difficult stool passage by softening feces and increasing intestinal water content.
  • Bowel preparation: Facilitates colon cleansing before colonoscopy, sigmoidoscopy, or surgical procedures.
  • Pre‑operative cleansing: Provides effective bowel evacuation prior to abdominal surgeries.

How It Works

  • Macrogol 3350 is a high‑molecular‑weight polyethylene glycol that is not absorbed from the gastrointestinal tract. It binds water molecules, creating an osmotic gradient that retains water in the intestinal lumen. The added electrolytes (sodium hydrogen carbonate, potassium chloride, sodium chloride) maintain electrolyte balance while the increased fluid softens stool and stimulates peristalsis, leading to bowel evacuation.

Side Effects

Macrogol En Elektrolyten Aurobindo may cause a range of adverse reactions, most of which are mild and transient.

Common Side Effects

  • Nausea: mild stomach upset after ingestion.
  • Abdominal bloating: feeling of fullness or distension.
  • Flatulence: increased intestinal gas.
  • Diarrhea: loose stools if dose exceeds need.
  • Abdominal cramps: intermittent cramping discomfort.

Serious or Rare Side Effects

  • Severe dehydration: marked fluid loss requiring medical attention.
  • Electrolyte imbalance: abnormal sodium or potassium levels.
  • Allergic reaction: rash, itching, or swelling.
  • Colonic perforation: rare but serious intestinal injury.

Precautions & Warnings

Before using Macrogol En Elektrolyten Aurobindo, consider the following precautions to ensure safe and effective therapy.

  • Assess hydration status: ensure patient is not severely dehydrated before initiating therapy.
  • Monitor electrolytes: check serum sodium and potassium levels in patients at risk.
  • Use with caution in renal impairment: reduced kidney function may affect electrolyte handling.
  • Avoid in known hypersensitivity: discontinue if allergic signs appear.
  • Do not exceed recommended volume: follow prescriber instructions to prevent fluid overload.
  • Store at room temperature: keep in the original container, protect from moisture and direct sunlight.

Avoid Interactions

Macrogol En Elektrolyten Aurobindo can interact with other medicines; awareness of these interactions helps prevent complications.

Major Interactions (Avoid)

  • Concurrent osmotic laxatives: may cause excessive fluid and electrolyte loss.
  • Strong diuretics: increase risk of electrolyte disturbances when combined.

Moderate Interactions (Monitor Closely)

  • NSAIDs: may affect renal function, enhancing risk of fluid imbalance.
  • Anticholinergic agents: could reduce the laxative effect.
  • ACE inhibitors or ARBs: monitor kidney function and electrolytes.
  • Oral electrolyte supplements: may alter intended electrolyte balance.

Frequently Asked Questions

Macrogol En Elektrolyten Aurobindo is an oral osmotic laxative indicated for the relief of occasional constipation and for bowel cleansing before diagnostic procedures such as colonoscopy or before certain surgical interventions.

Macrogol 3350 is a high‑molecular‑weight polyethylene glycol that remains in the gastrointestinal tract. It attracts and retains water in the intestinal lumen, softening stool and increasing volume, which stimulates peristalsis and promotes natural evacuation.

The appropriate dose is determined by the prescribing healthcare professional based on the patient’s age, weight, indication and clinical response. Dosing instructions should always be followed as written on the prescription label.

Safety data in pregnancy and lactation are limited. It should only be used when the potential benefit to the mother outweighs any possible risk to the fetus or infant, and under medical supervision.

Enquiries are submitted via the product page on gnhindia.com, where you specify the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Compared with stimulant laxatives, macrogol‑based solutions act osmotically and are generally gentler on the bowel, causing fewer cramping episodes. Unlike sodium phosphate preparations, the added electrolytes help maintain fluid balance, making it suitable for patients who need controlled bowel cleansing.

Store the oral solution at room temperature, below 25 °C, in the original container. Protect it from moisture, direct sunlight and extreme temperatures to preserve stability and potency.

The product is supplied as a clear oral solution. It is typically mixed with a measured amount of water or other clear fluid and taken by mouth as directed by the prescriber, usually in divided doses for bowel preparation or as a single dose for constipation relief.

Serious adverse events, although rare, include severe dehydration, significant electrolyte disturbances (especially sodium or potassium), allergic reactions such as rash or swelling, and, in extreme cases, colonic perforation. Prompt medical attention is required if any of these occur.

The product should be avoided in individuals with known hypersensitivity to any component, in patients with intestinal obstruction, perforation, or severe inflammatory bowel disease, and in those with severe renal impairment unless specifically advised by a physician.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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