Product image of Macrogol En Elektrolyten Aurobindo (Sodium Hydrogen Carbonate, Potassium Chloride, Sodium Chloride, Macrogol 3350) supplied by GNH India

Macrogol En Elektrolyten Aurobindo

Active Ingredient:
Sodium Hydrogen Carbonate, Potassium Chloride, Sodium Chloride, Macrogol 3350
Origin:
EU

Macrogol En Elektrolyten Aurobindo (Sodium Hydrogen Carbonate, Potassium Chloride, Sodium Chloride, Macrogol 3350)

Macrogol 3350, the active ingredient in Macrogol En Elektrolyten Aurobindo, is an osmotic laxative presented as an oral solution for oral use. It treats constipation and is used to prepare the bowel before diagnostic procedures in adults and children.

GNH India supplies Macrogol En Elektrolyten Aurobindo as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Aurobindo Pharma B.V.

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Indications & Clinical Uses

Macrogol En Elektrolyten Aurobindo, an osmotic laxative, is used to manage conditions that require bowel cleansing or relief of constipation.

  • Constipation: facilitates soft stool formation and promotes regular bowel movements.
  • Bowel preparation for colonoscopy: provides effective intestinal cleansing to improve visualization.
  • Pre‑operative bowel cleansing: clears the colon before abdominal surgery to reduce infection risk.

How It Works

  • Macrogol 3350 is a high‑molecular‑weight polyethylene glycol that remains in the intestinal lumen and creates an osmotic gradient, drawing water into the gut. The added electrolytes (sodium hydrogen carbonate, potassium chloride, sodium chloride) help maintain electrolyte balance while the increased water content softens stool and stimulates peristalsis, resulting in bowel evacuation.

Side Effects

Macrogol En Elektrolyten Aurobindo may cause a range of adverse reactions, most of which are mild and transient.

Common Side Effects

  • Abdominal bloating: feeling of fullness or distension in the abdomen.
  • Flatulence: increased intestinal gas.
  • Nausea: mild sensation of queasiness.
  • Diarrhea: loose stools, especially with higher doses.

Serious or Rare Side Effects

  • Electrolyte imbalance: abnormal serum sodium or potassium levels.
  • Severe dehydration: marked loss of body fluids.
  • Allergic reaction: rash, itching, swelling, or difficulty breathing.

Precautions & Warnings

When using Macrogol En Elektrolyten Aurobindo, consider the following precautions.

  • Renal impairment: monitor fluid and electrolyte status.
  • Heart failure: avoid excessive fluid shifts.
  • Pregnancy and lactation: use only if clearly needed.
  • Elderly patients: start with lower dose to reduce risk of dehydration.
  • Concurrent laxatives: avoid combining to prevent electrolyte disturbances.
  • Store at ambient temperature: keep in original container, protect from moisture and direct sunlight.

Avoid Interactions

Macrogol En Elektrolyten Aurobindo can interact with other medicines; awareness of the interaction level is important.

Major Interactions (Avoid)

  • Loop diuretics: may exacerbate electrolyte loss and dehydration.
  • Sodium‑containing medications: can increase risk of hypernatremia.

Moderate Interactions (Monitor Closely)

  • Anticholinergic agents: may reduce efficacy of bowel cleansing.
  • Opioid analgesics: may counteract laxative effect, requiring dose adjustment.
  • Mineral supplements (e.g., calcium, iron): may bind to the solution and reduce effectiveness.

Frequently Asked Questions

Macrogol En Elektrolyten Aurobindo is an oral osmotic laxative used to relieve constipation and to cleanse the bowel before diagnostic procedures such as colonoscopy or before certain surgeries. The formulation combines macrogol 3350 with electrolytes to promote safe and effective bowel evacuation.

Macrogol 3350 is a large polyethylene glycol polymer that is not absorbed from the gastrointestinal tract. It retains water in the intestinal lumen by creating an osmotic gradient, softening the stool. The accompanying electrolytes help maintain normal serum electrolyte levels while the increased fluid volume stimulates peristalsis.

The dose of Macrogol En Elektrolyten Aurobindo is individualized by the prescribing healthcare professional based on the patient’s age, weight, severity of constipation, and the intended use (e.g., routine relief versus bowel preparation). Patients should follow the prescriber’s instructions and not adjust the dose on their own.

Safety data for use in pregnancy and lactation are limited. The product should only be used if the potential benefit justifies any possible risk to the fetus or infant, and this decision must be made by a qualified healthcare provider. Women who are pregnant or nursing should discuss alternatives with their doctor.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide. After submission, the sales team will verify trade or institutional credentials and respond with pricing, availability, shipping details and any necessary import documentation.

Macrogol En Elektrolyten Aurobindo combines macrogol 3350 with balanced electrolytes, offering effective bowel cleansing while minimizing electrolyte disturbances. Compared with older agents such as sodium phosphate solutions, it generally provides a gentler osmotic effect and a lower risk of severe dehydration, making it suitable for a broader patient population.

The product should be stored at ambient temperature, below 25 °C, in its original container. Protect it from moisture, direct sunlight, and extreme temperature fluctuations. Ensure the bottle is tightly closed after each use to maintain stability and prevent contamination.

The oral solution is taken by mouth, usually after shaking the bottle gently to ensure uniform mixing of the electrolytes. It is typically consumed in measured doses as directed by a healthcare professional, often followed by a clear fluid to aid bowel cleansing.

Serious risks include electrolyte imbalance, severe dehydration, and rare allergic reactions that may present as rash, swelling, or breathing difficulty. Patients should seek immediate medical attention if they experience signs of significant fluid loss, abnormal heart rhythm, or any signs of an allergic response.

The product should be avoided in individuals with known hypersensitivity to macrogol or any of the electrolyte components. It is also contraindicated in patients with intestinal obstruction, perforation, or severe renal or cardiac failure where fluid shifts could be hazardous. A healthcare professional should assess suitability before use.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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