Product image of Macrogol En Elektrolyten Naturel Junior Intergal (Sodium Hydrogen Carbonate, Potassium Chloride, Sodium Chloride, Macrogol 3350) supplied by GNH India

Macrogol En Elektrolyten Naturel Junior Intergal

Active Ingredient:
Sodium Hydrogen Carbonate, Potassium Chloride, Sodium Chloride, Macrogol 3350
Origin:
EU

Macrogol En Elektrolyten Naturel Junior Intergal (Sodium Hydrogen Carbonate, Potassium Chloride, Sodium Chloride, Macrogol 3350)

Macrogol 3350, the active ingredient in Macrogol En Elektrolyten Naturel Junior Intergal, is an osmotic laxative presented as an oral solution for oral use. It treats constipation, prepares the bowel for procedures, and helps replenish electrolytes in pediatric patients.

GNH India supplies Macrogol En Elektrolyten Naturel Junior Intergal as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Intergal Pharma Ireland Limited

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Indications & Clinical Uses

Macrogol En Elektrolyten Naturel Junior is an osmotic laxative and electrolyte solution used to manage conditions affecting bowel function and fluid balance.

  • Constipation: softens stool and promotes regular bowel movements.
  • Bowel preparation: clears the intestinal tract before diagnostic or surgical procedures.
  • Electrolyte replacement: restores sodium, potassium and chloride levels during dehydration or after laxative therapy.

How It Works

  • Macrogol 3350 creates an osmotic gradient that retains water within the intestinal lumen, increasing stool water content and softening the stool. The accompanying electrolytes—sodium hydrogen carbonate, potassium chloride and sodium chloride—maintain fluid and electrolyte balance, supporting safe bowel cleansing and preventing significant shifts in plasma electrolytes.

Side Effects

Adverse reactions may occur with any osmotic laxative and electrolyte solution.

Common Side Effects

  • Abdominal bloating: mild distension of the abdomen.
  • Nausea: feeling of sickness or urge to vomit.
  • Flatulence: increased intestinal gas.
  • Mild diarrhea: loose stools occurring with initial dosing.
  • Transient electrolyte imbalance: mild changes in serum sodium or potassium.

Serious or Rare Side Effects

  • Severe dehydration: marked loss of body water.
  • Severe electrolyte disturbances: significant hypo‑ or hyper‑natremia, hyper‑kalemia.
  • Allergic reaction: rash, itching, or swelling.
  • Severe abdominal pain: persistent or worsening pain.
  • Colonic perforation: rare but life‑threatening intestinal injury.

Precautions & Warnings

Before initiating therapy, consider patient‑specific factors and monitor for complications.

  • Renal function: assess kidney status, especially in patients with impairment.
  • Electrolyte monitoring: check serum sodium, potassium and chloride during prolonged use.
  • Bowel obstruction: avoid in patients with known or suspected obstruction.
  • Pediatric dosing: adjust dose according to age and weight under medical supervision.
  • Concomitant laxatives: avoid using other osmotic agents simultaneously.
  • Store at room temperature: keep in the original container, protect from moisture and direct sunlight.

Avoid Interactions

Macrogol En Elektrolyten Naturel Junior may interact with other medicines that affect fluid or electrolyte balance.

Major Interactions (Avoid)

  • Other osmotic laxatives: risk of excessive fluid loss and electrolyte imbalance.
  • High‑dose mineral supplements: may cause dangerous electrolyte shifts.
  • Loop diuretics: can amplify dehydration and electrolyte disturbances.

Moderate Interactions (Monitor Closely)

  • Anticholinergic agents: may reduce laxative efficacy.
  • NSAIDs: potential additive renal stress.
  • ACE inhibitors or ARBs: monitor blood pressure and electrolytes closely.

Frequently Asked Questions

Macrogol En Elektrolyten Naturel Junior is an oral osmotic laxative and electrolyte solution indicated for relieving constipation, preparing the bowel before diagnostic or surgical procedures, and replenishing essential electrolytes such as sodium, potassium and chloride during dehydration or after laxative therapy.

Macrogol 3350 acts by creating an osmotic gradient that draws water into the intestinal lumen, increasing stool water content and softening the stool. The added electrolytes—sodium hydrogen carbonate, potassium chloride and sodium chloride—help maintain fluid and electrolyte balance while the bowel is being cleared.

The specific dose of Macrogol En Elektrolyten Naturel Junior is determined by the prescribing healthcare professional based on the patient’s age, weight, clinical condition and therapeutic goal. Patients should follow the prescriber’s instructions and not adjust the dose on their own.

Safety data for Macrogol En Elektrolyten Naturel Junior in pregnancy or lactation are limited. Healthcare providers should evaluate the potential benefits against possible risks before prescribing it to pregnant or breastfeeding individuals.

To place an order, submit an enquiry on the product page at gnhindia.com with the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements) and the necessary import documentation.

Compared with other osmotic laxatives, Macrogol En Elektrolyten Naturel Junior combines macrogol 3350 with a balanced electrolyte mix, offering effective stool softening while helping to maintain electrolyte homeostasis. Some alternatives lack the added electrolytes, which may increase the risk of electrolyte disturbances during prolonged use.

Store the oral solution at room temperature, preferably below 25 °C. Keep the container tightly closed, protect it from moisture and direct sunlight, and retain it in the original packaging until use.

Macrogol En Elektrolyten Naturel Junior is taken orally as a liquid solution. The prescribed volume is measured using a calibrated device and ingested directly or mixed with a small amount of fluid, following the healthcare professional’s guidance.

Serious risks include severe dehydration, significant electrolyte disturbances (such as hyponatremia or hyperkalemia), allergic reactions, and, in rare cases, colonic perforation. Patients should seek immediate medical attention if they experience extreme abdominal pain, persistent vomiting, or signs of severe electrolyte imbalance.

Individuals with known or suspected bowel obstruction, severe renal impairment, or hypersensitivity to macrogol or any of the electrolyte components should avoid using Macrogol En Elektrolyten Naturel Junior. It is also contraindicated in patients who are already receiving other osmotic laxatives without medical supervision.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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