Product image of Macrogol En Elektrolyten Sandoz (Sodium Hydrogen Carbonate, Potassium Chloride, Sodium Chloride, Macrogol 3350) supplied by GNH India

Macrogol En Elektrolyten Sandoz

Active Ingredient:
Sodium Hydrogen Carbonate, Potassium Chloride, Sodium Chloride, Macrogol 3350
Origin:
EU

Macrogol En Elektrolyten Sandoz (Sodium Hydrogen Carbonate, Potassium Chloride, Sodium Chloride, Macrogol 3350)

Macrogol 3350, the active ingredient in Macrogol En Elektrolyten Sandoz, is an osmotic laxative presented as an oral solution for oral use. It treats constipation and is employed as a bowel‑preparation agent in adults and children when directed by a healthcare professional.

GNH India supplies Macrogol En Elektrolyten Sandoz as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, offering consistent product quality, regulatory compliance, and reliable cold‑chain‑free logistics for global distribution through established partnerships with regional distributors.

Manufacturer / TM Owner

Sandoz B.V.

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

Macrogol En Elektrolyten Sandoz, an osmotic laxative, is used to manage conditions affecting bowel transit and stool consistency.

  • Constipation: softens stool and promotes regular bowel movements, relieving occasional or chronic constipation.
  • Bowel preparation for diagnostic procedures: clears intestinal contents to enable clear visualization during colonoscopy, sigmoidoscopy or pre‑operative assessment.
  • Chronic idiopathic constipation in adults: provides sustained stool softening to improve quality of life when conventional fiber therapy is insufficient.

How It Works

  • Macrogol 3350, a high‑molecular‑weight polyethylene glycol, is minimally absorbed and creates an osmotic gradient that retains water within the intestinal lumen, thereby softening stool. The accompanying electrolytes (sodium hydrogen carbonate, potassium chloride, sodium chloride) help maintain fluid and electrolyte balance, supporting safe and effective bowel cleansing.

Side Effects

Macrogol En Elektrolyten Sandoz may cause a range of adverse reactions, most of which are mild and transient.

Common Side Effects

  • Abdominal bloating
  • Flatulence
  • Nausea
  • Diarrhea
  • Abdominal cramps
  • Thirst

Serious or Rare Side Effects

  • Severe electrolyte imbalance (e.g., hyponatremia, hypokalemia)
  • Allergic reactions such as rash, angioedema, or anaphylaxis
  • Severe abdominal pain or colonic perforation (very rare)

Precautions & Warnings

Before initiating therapy with Macrogol En Elektrolyten Sandoz, consider the following precautions to ensure safe use.

  • Assess renal function: adjust use in patients with severe renal impairment.
  • Monitor electrolyte status: especially potassium and sodium levels during prolonged therapy.
  • Use with caution in inflammatory bowel disease: risk of worsening symptoms.
  • Avoid in complete bowel obstruction: drug requires intestinal transit.
  • Store at ambient temperature: keep in the original container, protect from moisture and direct sunlight.

Avoid Interactions

Macrogol En Elektrolyten Sandoz can interact with other medicines; awareness of significant interactions helps prevent complications.

Major Interactions (Avoid)

  • Concurrent use with other osmotic laxatives: may cause severe electrolyte disturbances.
  • Co‑administration with diuretics: increased risk of dehydration and electrolyte loss.
  • Use with mineral oil: may reduce efficacy of both agents.

Moderate Interactions (Monitor Closely)

  • Combination with anticholinergic agents: may reduce bowel motility, affecting effectiveness.
  • Concurrent use with NSAIDs: monitor for gastrointestinal discomfort.
  • Use with oral rehydration solutions: monitor electrolyte balance.

Frequently Asked Questions

Macrogol En Elektrolyten Sandoz is an oral osmotic laxative indicated for the relief of constipation and for bowel preparation before diagnostic procedures such as colonoscopy. It works by softening stool and promoting regular bowel movements.

Macrogol 3350 is a high‑molecular‑weight polyethylene glycol that is not absorbed from the gut. It creates an osmotic gradient that draws water into the intestinal lumen, softening the stool. The added electrolytes help maintain fluid balance while the bowel is cleared.

The dosage of Macrogol En Elektrolyten Sandoz is individualized. A qualified prescriber determines the amount, frequency and duration based on the patient’s age, severity of constipation or the requirements of the planned procedure.

Safety data in pregnancy and lactation are limited. The product should only be used when the potential benefit justifies any possible risk to the fetus or infant, and this decision must be made by a healthcare professional.

To place an order, submit an enquiry on the product page at gnhindia.com with the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Macrogol En Elektrolyten Sandoz combines macrogol 3350 with electrolytes, offering effective stool softening while helping to preserve electrolyte balance. Compared with plain polyethylene glycol solutions, the added salts may reduce the risk of electrolyte shifts, and it is generally better tolerated than lactulose, which can cause more gas and bloating.

Store the oral solution at ambient temperature, preferably below 25 °C. Keep the container tightly closed, protect it from moisture and direct sunlight, and ensure the label remains legible. Do not freeze the solution.

The product is supplied as an oral solution. It should be measured accurately, mixed with a suitable amount of water if required, and taken as directed by the prescribing clinician, usually on an empty stomach for bowel preparation or as advised for constipation relief.

Serious risks include severe electrolyte disturbances (such as hyponatremia or hypokalemia), dehydration, allergic reactions that may manifest as rash or anaphylaxis, and, in extremely rare cases, colonic perforation. Patients should seek immediate medical attention if they experience severe abdominal pain, swelling, or signs of an allergic reaction.

The product should be avoided in individuals with complete bowel obstruction, known hypersensitivity to macrogol or any of the electrolytes, and in patients with severe renal impairment unless closely monitored. Consultation with a healthcare professional is essential before use in these populations.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.