Product image of Macrogol Plus Elektrolyte Hexal (Sodium Hydrogen Carbonate, Potassium Chloride, Sodium Chloride, Macrogol 3350) supplied by GNH India

Macrogol Plus Elektrolyte Hexal

Active Ingredient:
Sodium Hydrogen Carbonate, Potassium Chloride, Sodium Chloride, Macrogol 3350
Origin:
EU

Macrogol Plus Elektrolyte Hexal (Sodium Hydrogen Carbonate, Potassium Chloride, Sodium Chloride, Macrogol 3350)

Macrogol 3350 with sodium hydrogen carbonate, potassium chloride and sodium chloride, the active ingredient in Macrogol Plus Elektrolyte Hexal, is an osmotic laxative presented as an oral formulation for oral use. It is used to relieve constipation and to replace electrolytes in patients requiring bowel cleansing.

GNH India supplies Macrogol Plus Elektrolyte Hexal as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Hexal Ag

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Indications & Clinical Uses

Macrogol Plus Elektrolyte Hexal is used as an osmotic laxative and electrolyte supplement in conditions affecting bowel function and fluid balance.

  • Constipation: helps soften stool and promote bowel movements by increasing intestinal water content.
  • Electrolyte replacement: provides sodium, potassium and chloride to maintain fluid balance during laxative therapy.
  • Bowel preparation for diagnostic procedures: facilitates intestinal cleansing while preserving electrolyte balance.

How It Works

  • Macrogol 3350 creates an osmotic gradient in the intestinal lumen, drawing water into the bowel to increase stool volume and soften consistency. The accompanying electrolytes (sodium hydrogen carbonate, potassium chloride, sodium chloride) are absorbed to help maintain systemic electrolyte and fluid homeostasis during the laxative effect.

Side Effects

Macrogol Plus Elektrolyte Hexal may cause a range of adverse reactions, most of which are mild and transient.

Common Side Effects

  • Abdominal bloating: feeling of fullness or swelling in the abdomen.
  • Flatulence: increased intestinal gas.
  • Nausea: mild sensation of wanting to vomit.
  • Mild abdominal cramps: occasional cramping sensations.
  • Diarrhea: loose stools occurring more frequently.
  • Thirst: increased desire for fluids.

Serious or Rare Side Effects

  • Severe electrolyte imbalance: abnormal sodium or potassium levels.
  • Dehydration: excessive loss of body water.
  • Allergic reaction: rash, swelling, or difficulty breathing.
  • Severe abdominal pain: intense, persistent pain.
  • Colonic perforation: rare tearing of the colon wall.
  • Anaphylaxis: life‑threatening systemic allergic response.

Precautions & Warnings

Before using Macrogol Plus Elektrolyte Hexal, consider the following safety measures.

  • Renal impairment: monitor electrolyte levels closely.
  • Heart failure: use with caution due to sodium load.
  • Pregnancy: consult a healthcare professional before use.
  • Elderly patients: start with a lower dose to avoid dehydration.
  • Drug interactions: review concomitant medications that affect electrolytes.
  • Store at ambient temperature: keep in the original container, protect from moisture and heat.

Avoid Interactions

Macrogol Plus Elektrolyte Hexal can interact with other medicines that influence electrolyte balance or gastrointestinal function.

Major Interactions (Avoid)

  • Potassium‑sparing diuretics: may cause hyperkalemia.
  • ACE inhibitors or ARBs: risk of increased potassium levels.
  • Sodium‑containing IV fluids: risk of sodium overload.

Moderate Interactions (Monitor Closely)

  • Stimulant laxatives: may increase risk of electrolyte disturbances.
  • Antacids containing sodium bicarbonate: additive sodium load.
  • Diuretics: may exacerbate fluid loss.

Frequently Asked Questions

Macrogol Plus Elektrolyte Hexal is indicated for the relief of occasional constipation and for electrolyte replacement during bowel cleansing procedures. The combination of macrogol 3350 with sodium hydrogen carbonate, potassium chloride and sodium chloride helps soften stool while maintaining fluid and electrolyte balance.

Macrogol 3350 acts as an osmotic agent. It remains largely unabsorbed in the gastrointestinal tract and draws water into the intestinal lumen, increasing stool volume and softness. The added electrolytes are absorbed to support normal plasma electrolyte concentrations during the laxative effect.

The appropriate dose is individualized by the prescribing healthcare professional based on the patient’s age, severity of constipation, renal function and electrolyte status. Patients should follow the prescriber’s instructions and not adjust the amount on their own.

Safety data in pregnancy and lactation are limited. The product should only be used if the potential benefit justifies any possible risk to the fetus or infant, and this decision must be made by a qualified healthcare provider.

To place an order, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any required import documentation.

Compared with stimulant laxatives, macrogol 3350 provides a gentler, osmotic mechanism that is less likely to cause cramping. Unlike sodium phosphate preparations, it includes electrolytes that help prevent significant shifts in sodium and potassium levels during treatment.

Store the product at ambient temperature, preferably below 25 °C. Keep it in the original packaging, protect it from moisture and direct sunlight, and ensure the container is tightly closed to maintain product stability.

The oral powder should be dissolved in the recommended volume of water or clear fluid as instructed by the prescriber, then taken by mouth. It is typically consumed once daily, but the exact schedule is determined by the healthcare professional.

Serious risks include severe electrolyte imbalance, dehydration, allergic reactions such as rash or anaphylaxis, and, in rare cases, colonic perforation. Patients should seek immediate medical attention if they experience symptoms like extreme abdominal pain, swelling, or signs of an allergic reaction.

The product should be avoided in individuals with known hypersensitivity to any of its ingredients, severe renal impairment, uncontrolled heart failure, or in patients with intestinal obstruction. A healthcare professional should evaluate suitability before initiating therapy.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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