Macrolief (Sodium Hydrogen Carbonate, Potassium Chloride, Sodium Chloride, Macrogol 3350)

The formulation supplies sodium, potassium and chloride ions to replace lost electrolytes, while macrogol 3350 (polyethylene glycol 3350) remains in the gastrointestinal tract, drawing water into the lumen. This osmotic effect softens stool and promotes bowel movements, while the bicarbonate component helps neutralize excess gastric acid.

The specific dose of Macrolief is determined by the prescribing healthcare professional based on the patient’s condition, age, weight and electrolyte status. Dosage may vary for dehydration versus constipation, and the prescriber will provide detailed instructions on volume and frequency.

Safety data for Macrolief in pregnancy and lactation are limited. It should only be used if the potential benefit to the mother outweighs any possible risk to the fetus or infant. Healthcare providers should evaluate the individual situation and discuss alternatives when appropriate.

To request Macrolief, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any temperature requirements) and the necessary import documentation.

Macrolief combines electrolyte replacement with macrogol 3350, offering both rehydration and osmotic laxative effects. Unlike stimulant laxatives, macrogol 3350 works by retaining water in the bowel, resulting in a gentler, more predictable stool softening. The added electrolytes also help prevent the fluid shifts sometimes seen with pure laxative preparations.

Macrolief should be stored at ambient temperature, preferably below 25 °C. Keep the container tightly closed, protect it from moisture, direct sunlight and extreme temperatures. Do not freeze the solution. Follow any additional handling instructions provided on the label to maintain product integrity.

Macrolief is taken orally as a liquid solution. The prescriber will specify the volume to be consumed and the frequency, which may be a single dose or divided doses throughout the day. It can be taken with or without food unless otherwise directed.

Serious risks include severe electrolyte disturbances such as hyperkalemia or hyponatremia, especially in patients with renal or cardiac disease, and rare allergic reactions that can lead to anaphylaxis. Persistent abdominal pain, severe diarrhea or signs of dehydration should prompt immediate medical evaluation.

Macrolief should be avoided in individuals with known hypersensitivity to any of its components, in patients with severe renal impairment, uncontrolled heart failure, or in those who are already receiving high‑dose electrolyte supplements that could cause overload. A healthcare professional should assess suitability before prescribing.