Product image of Madopark Quick Mite (Benserazide Hydrochloride, Levodopa) supplied by GNH India

Madopark Quick Mite

Active Ingredient:
Benserazide Hydrochloride, Levodopa
Origin:
EU

Madopark Quick Mite (Benserazide Hydrochloride, Levodopa)

Levodopa/Benserazide, the active ingredient in Madopark Quick Mite, is a dopamine precursor/DOPA decarboxylase inhibitor combination presented as an oral tablet for oral use. It is used to treat Parkinson's disease in adults by restoring central dopamine levels, helping to improve motor function and reduce rigidity.

GNH India supplies Madopark Quick Mite as a licensed, GDP‑compliant international pharmaceutical supplier, adhering to EU GMP standards and providing reliable sourcing for hospitals, pharmacies and clinics worldwide. All batches are manufactured under strict quality control and are distributed under secure logistics to ensure product integrity.

Manufacturer / TM Owner

Roche Ab

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Indications & Clinical Uses

Madopark Quick Mite, a levodopa/benserazide combination, is indicated for the management of Parkinsonian disorders.

  • Parkinson's disease (early stage): improves motor symptoms such as tremor and bradykinesia.
  • Parkinson's disease (advanced stage): helps maintain functional mobility when used with adjunct therapies.
  • Parkinsonian syndrome secondary to dopamine deficiency: restores dopaminergic activity to reduce rigidity and improve gait.

How It Works

  • Levodopa crosses the blood‑brain barrier and is decarboxylated to dopamine within the central nervous system. Benserazide, a peripheral DOPA decarboxylase inhibitor, prevents conversion of levodopa to dopamine outside the brain, increasing the amount of levodopa that reaches the CNS and thereby enhancing central dopaminergic neurotransmission.

Side Effects

Common Side Effects

  • Nausea: mild to moderate gastrointestinal upset.
  • Orthostatic hypotension: dizziness upon standing.
  • Dyskinesia: involuntary movements, especially with higher doses.
  • Insomnia: difficulty falling or staying asleep.
  • Dry mouth: reduced salivation.
  • Headache: transient cranial discomfort.

Serious or Rare Side Effects

  • Neuroleptic malignant syndrome: life‑threatening reaction with fever and rigidity.
  • Severe hypotension: marked drop in blood pressure leading to fainting.
  • Cardiac arrhythmias: irregular heart rhythms.
  • Psychosis: hallucinations or delusional thoughts.
  • Severe allergic reactions: rash, swelling, or anaphylaxis.

Precautions & Warnings

Before initiating therapy, consider patient‑specific factors and monitor for adverse reactions.

  • Renal impairment: adjust dose and monitor renal function.
  • Hepatic disease: use with caution; monitor liver enzymes.
  • Cardiovascular disease: watch for hypotension and arrhythmias.
  • Concomitant MAO‑B inhibitors: avoid due to risk of hypertensive crisis.
  • Pregnancy and lactation: safety not established; only use if benefits outweigh risks.
  • Store at ambient temperature: keep below 25 °C, in the original container, protected from moisture and light.

Avoid Interactions

Drug interactions may alter efficacy or increase toxicity.

Major Interactions (Avoid)

  • Non‑selective MAO inhibitors: risk of hypertensive crisis.
  • Antipsychotics (e.g., haloperidol): may diminish antiparkinson effect.
  • High‑dose pyridoxine (vitamin B6): accelerates peripheral levodopa metabolism.

Moderate Interactions (Monitor Closely)

  • Iron supplements: reduce levodopa absorption; separate dosing by at least 2 hours.
  • Antihypertensives: additive blood‑pressure lowering effect.
  • SSRIs and SNRIs: may increase risk of serotonin syndrome when combined with MAO‑B inhibitors.

Frequently Asked Questions

Madopark Quick Mite is prescribed to manage the motor symptoms of Parkinson's disease. By increasing dopamine levels in the brain, it helps reduce tremor, stiffness, and slowness of movement, improving overall functional ability in patients with Parkinsonian disorders.

Levodopa is a precursor that crosses the blood‑brain barrier and is converted into dopamine, the neurotransmitter lacking in Parkinson's disease. Benserazide blocks the peripheral enzyme that would otherwise convert levodopa outside the brain, ensuring more levodopa reaches the central nervous system for dopamine synthesis.

The dosage of Madopark Quick Mite is individualized by the prescribing clinician based on disease severity, patient age, and response to therapy. Only a qualified healthcare professional should determine the appropriate dose and titration schedule.

Safety data for levodopa/benserazide in pregnancy and lactation are limited. It should be used only if the potential benefit justifies any possible risk to the fetus or infant, and the decision must be made by the treating physician.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details, and any necessary import documentation.

Madopark Quick Mite combines levodopa with benserazide, offering higher central dopamine availability than levodopa alone. Compared with dopamine agonists, it provides more potent symptom control but may have a higher risk of motor complications such as dyskinesia. Choice of therapy depends on individual patient factors and treatment goals.

Store the tablets at ambient temperature, preferably below 25 °C, in the original packaging to protect them from moisture and light. Keep the product out of reach of children and avoid storing in humid or excessively hot environments.

Madopark Quick Mite is taken orally with a full glass of water, usually on an empty stomach to improve absorption. Patients should follow the timing and dosing instructions provided by their healthcare professional and avoid taking it with high‑protein meals that may interfere with levodopa uptake.

Serious risks include neuroleptic malignant syndrome, severe hypotension, cardiac arrhythmias, and psychotic reactions such as hallucinations. Patients should be monitored closely for any sudden changes in mental status, blood pressure, or heart rhythm, and seek immediate medical attention if severe symptoms occur.

Patients with known hypersensitivity to levodopa, benserazide, or any excipients in the formulation should avoid the product. It is also contraindicated in individuals taking non‑selective MAO inhibitors or those with uncontrolled narrow‑angle glaucoma, as it may exacerbate intra‑ocular pressure.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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