Mag 2 (Magnesium Carbonate)

• Magnesium carbonate is used as an antacid and magnesium supplement to address gastrointestinal acidity and magnesium deficiency.
• Heartburn: alleviates burning sensation by neutralizing stomach acid.
• Dyspepsia: reduces post‑meal discomfort and fullness.
• Magnesium deficiency: restores normal magnesium levels for muscle and nerve function.

• Magnesium carbonate reacts with gastric hydrochloric acid to form magnesium chloride, carbon dioxide and water, thereby raising gastric pH and reducing acidity. The released elemental magnesium is absorbed in the intestine and participates in enzymatic reactions, ATP synthesis, and regulation of muscle, nerve and cardiac activity. It also contributes to the maintenance of electrolyte balance and supports bone mineralization.

Magnesium carbonate may cause a range of adverse reactions, most of which are mild and transient.

Common Side Effects

• Abdominal discomfort or cramping.
• Diarrhea or loose stools.
• Flatulence and bloating.
• Nausea or mild stomach upset.
• Constipation (less common).

Serious or Rare Side Effects

• Hypermagnesemia, especially in renal impairment.
• Severe allergic reaction such as anaphylaxis.
• Electrolyte imbalance leading to cardiac arrhythmia.
• Kidney function impairment.
• Persistent vomiting or severe abdominal pain.

• When using magnesium carbonate, certain precautions should be observed to ensure safety.
• Assess renal function: patients with impaired kidneys may accumulate magnesium.
• Monitor serum magnesium: avoid hypermagnesemia.
• Avoid concurrent high‑dose magnesium supplements: risk of excess magnesium.
• Caution with cardiac conditions: may affect conduction in heart block or when combined with calcium‑channel blockers.
• Pregnant or breastfeeding women: consult a healthcare professional before use.
• Store at room temperature: keep in the original container, protect from moisture and direct sunlight.

Magnesium carbonate can interact with several medicines, altering their absorption or effects.

Major Interactions (Avoid)

• Tetracycline antibiotics: reduced absorption and efficacy.
• Fluoroquinolone antibiotics: decreased bioavailability.
• Bisphosphonates: impaired absorption when taken together.

Moderate Interactions (Monitor Closely)

• ACE inhibitors or potassium‑sparing diuretics: increased risk of hyperkalemia.
• Digoxin: possible increase in serum levels.
• Calcium‑channel blockers: additive effects on cardiac conduction.