Product image of Magne B6 (Pyridoxine Hydrochloride, Magnesium Lactate Dihydrate) supplied by GNH India

Magne B6

Active Ingredient:
Pyridoxine Hydrochloride, Magnesium Lactate Dihydrate
Origin:
EU

Magne B6 (Pyridoxine Hydrochloride, Magnesium Lactate Dihydrate)

Pyridoxine hydrochloride, the active ingredient in Magne B6, is a vitamin B6 and magnesium supplement presented as an oral supplement for oral use. It helps address magnesium and vitamin B6 deficiencies in adults.

GNH India supplies Magne B6 as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Opella Healthcare France Sas

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Indications & Clinical Uses

Magne B6 is used to support metabolic pathways that depend on magnesium and vitamin B6.

  • Magnesium deficiency: helps restore normal magnesium levels and associated neuromuscular function.
  • Vitamin B6 deficiency: provides pyridoxine to support amino‑acid metabolism and neurotransmitter synthesis.
  • General nutritional support: contributes to overall micronutrient intake for adults with increased needs.

How It Works

  • Pyridoxine hydrochloride serves as a co‑factor for enzymes involved in amino‑acid transamination, decarboxylation and glycogenolysis, while magnesium lactate dissociates to supply magnesium ions that act as cofactors for ATP‑dependent reactions, neuromuscular transmission, and DNA synthesis. Together they facilitate enzymatic processes essential for energy metabolism and nerve function.

Side Effects

Magne B6 may be associated with a range of adverse reactions, which are generally classified by frequency and severity.

Common Side Effects

  • Gastrointestinal upset: nausea, abdominal discomfort or diarrhoea.
  • Headache: mild to moderate headache.
  • Dizziness: transient sensation of light‑headedness.
  • Skin reactions: mild rash or itching.

Serious or Rare Side Effects

  • Allergic reaction: urticaria, swelling of face, lips or throat requiring immediate medical attention.
  • Severe hypermagnesemia: muscle weakness, low blood pressure, respiratory depression in patients with renal impairment.
  • Hepatic dysfunction: elevated liver enzymes in rare cases.
  • Blood dyscrasias: rare cases of neutropenia or thrombocytopenia.

Precautions & Warnings

When considering Magne B6, several precautionary measures should be observed to ensure safe use.

  • Renal impairment: assess kidney function before use as magnesium excretion may be reduced.
  • Pregnancy and lactation: consult a healthcare professional before initiating therapy.
  • Drug interactions: review concomitant medications for potential magnesium or pyridoxine interactions.
  • Dosage adjustment: elderly or patients with gastrointestinal disorders may require modified dosing.
  • Store below 25°C: keep in the original container, protect from moisture and direct sunlight.

Avoid Interactions

Magne B6 can affect the pharmacokinetics or pharmacodynamics of certain medicines.

Major Interactions (Avoid)

  • Antibiotics (tetracyclines, quinolones): magnesium may chelate and reduce absorption; separate dosing by at least 2 hours.
  • Bisphosphonates: magnesium can impair oral bisphosphonate bioavailability; administer at different times.
  • Levothyroxine: magnesium may decrease absorption; separate administration.

Moderate Interactions (Monitor Closely)

  • Diuretics (loop, thiazide): may increase magnesium loss, monitor serum levels.
  • Anticonvulsants (phenytoin, carbamazepine): pyridoxine may reduce seizure threshold; monitor clinical response.
  • Oral contraceptives: high‑dose pyridoxine may affect hormone metabolism; observe for efficacy changes.

Frequently Asked Questions

Magne B6 is an over‑the‑counter nutritional supplement that provides both pyridoxine (vitamin B6) and magnesium. It is intended to help correct deficiencies of these nutrients, support normal amino‑acid metabolism, and maintain healthy neuromuscular and cardiovascular function in adults.

Pyridoxine hydrochloride is converted in the body to pyridoxal‑5‑phosphate, the active co‑enzyme form of vitamin B6. This co‑enzyme participates in over 100 enzymatic reactions, including amino‑acid transamination, neurotransmitter synthesis, and glycogen breakdown, thereby supporting metabolism and nerve function.

The appropriate dose of Magne B6 is determined by a qualified healthcare professional based on the individual’s age, clinical condition, and nutritional needs. Patients should follow the prescriber’s instructions and not exceed the recommended amount without medical advice.

Pregnant or breastfeeding individuals should consult their physician before using Magne B6. While pyridoxine and magnesium are essential nutrients, the correct dosage and safety profile must be evaluated by a healthcare provider to avoid potential risks to the mother or infant.

To request Magne B6, visit the product page on gnhindia.com, enter the desired quantity, and submit the enquiry form. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements) and necessary import documentation.

Magne B6 combines magnesium lactate and pyridoxine hydrochloride in a single oral formulation, offering the convenience of dual supplementation. Compared with single‑nutrient products, it may simplify dosing for patients who need both nutrients, though the specific salt forms and bioavailability can differ among brands.

Store Magne B6 below 25 °C in its original packaging, protecting it from moisture, heat and direct sunlight. Keep the container tightly closed and out of reach of children. No refrigeration is required for this oral supplement.

Magne B6 is taken orally, usually with water. The prescriber may advise taking it with food or on an empty stomach depending on individual tolerance and the presence of other medications. Swallow the tablet or capsule whole; do not crush or chew unless specifically instructed.

Serious adverse reactions, although rare, include severe allergic responses such as urticaria, facial swelling, or difficulty breathing, and signs of hypermagnesemia like muscle weakness, low blood pressure, or respiratory depression, especially in patients with impaired kidney function. Immediate medical attention is required if these occur.

Individuals with known hypersensitivity to pyridoxine, magnesium salts, or any excipients in the product should avoid Magne B6. Patients with severe renal failure, uncontrolled hypermagnesemia, or those taking medications that may interact significantly (e.g., certain antibiotics or bisphosphonates) should consult a healthcare professional before use.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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