Product image of Magneclo (Magnesium Chloride Hexahydrate) supplied by GNH India

Magneclo

Active Ingredient:
Magnesium Chloride Hexahydrate
Origin:
EU

Magneclo (Magnesium Chloride Hexahydrate)

Magnesium Chloride Hexahydrate, the active ingredient in Magneclo, is an electrolyte/mineral supplement presented as a solution for injection for intramuscular and intravenous use. It treats hypomagnesemia and magnesium deficiency in hospital and critical‑care settings.

GNH India supplies Magneclo as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, transplant centres, oncology centres, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Laboratoires Sterop

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Indications & Clinical Uses

Magneclo is used to replace magnesium in patients with electrolyte disturbances.

  • Hypomagnesemia: restores plasma magnesium levels and supports neuromuscular function.
  • Magnesium deficiency: corrects low magnesium concentrations and aids enzymatic processes.
  • Peri‑operative electrolyte replacement: provides rapid magnesium repletion during surgery or critical care.

How It Works

  • Magnesium chloride dissociates to release magnesium ions, which act as essential cofactors for over 300 enzymatic reactions, including ATP synthesis, protein translation, and ion channel regulation. The ions raise extracellular magnesium concentration, normalizing cellular membrane potential and modulating calcium influx, thereby restoring neuromuscular and cardiovascular function.

Side Effects

Magneclo may be associated with a range of adverse reactions, most of which are related to the route of administration or rapid changes in serum magnesium.

Common Side Effects

  • Injection site pain: mild discomfort at the injection site.
  • Flushing: transient warmth or redness of the skin.
  • Nausea: mild gastrointestinal upset.

Serious or Rare Side Effects

  • Hypermagnesemia: elevated serum magnesium that can cause cardiac arrhythmia or respiratory depression.
  • Allergic reaction: rash, itching, or anaphylaxis.
  • Cardiac arrest: severe conduction disturbances in extreme cases.

Precautions & Warnings

When using Magneclo, clinicians should observe several safety measures.

  • Assess serum magnesium: measure baseline levels before initiating therapy.
  • Monitor cardiac function: observe ECG for QT changes during infusion.
  • Adjust dose in renal impairment: reduce or avoid in patients with severe renal failure.
  • Avoid rapid infusion: administer over recommended time to prevent hypermagnesemia.
  • Pregnancy and lactation: use only if benefit outweighs risk, as data are limited.
  • Store at 2-8°C: keep refrigerated, protect from light, do not freeze or shake.

Avoid Interactions

Magneclo can interact with several medicines, requiring attention to avoid adverse outcomes.

Major Interactions (Avoid)

  • Calcium‑containing solutions: concurrent infusion may precipitate magnesium‑calcium salts.
  • Neuromuscular blockers: enhanced potentiation leading to prolonged muscle relaxation.
  • Loop diuretics: may increase magnesium loss, requiring careful monitoring.

Moderate Interactions (Monitor Closely)

  • ACE inhibitors: risk of additive hypotensive effect.
  • Aminoglycoside antibiotics: potential for increased neuromuscular blockade.
  • Proton pump inhibitors: may affect magnesium absorption, monitor levels.

Frequently Asked Questions

Magneclo is an injectable magnesium chloride solution used to correct low magnesium levels in patients with hypomagnesemia, magnesium deficiency, or those requiring rapid electrolyte replacement during surgery or critical‑care management.

After injection, magnesium chloride dissociates, releasing magnesium ions that serve as cofactors for many enzymatic reactions, help stabilize cell membranes, and modulate calcium channels, thereby restoring normal neuromuscular and cardiac function.

The dose of Magneclo is individualized by the prescribing clinician based on the patient’s serum magnesium level, clinical condition, renal function, and route of administration. No fixed regimen is provided here.

Safety data for Magneclo in pregnancy and lactation are limited. It should only be used when the potential benefit to the mother outweighs any possible risk to the fetus or infant, and under close medical supervision.

To order Magneclo, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including cold‑chain if needed) and import documentation.

Magneclo delivers magnesium as magnesium chloride, which provides a high proportion of free magnesium ions and allows rapid correction of serum levels. Compared with magnesium sulfate, it may have a slightly different electrolyte profile and is often chosen when a chloride load is acceptable or preferred.

Magneclo should be stored at 2‑8 °C, kept refrigerated, protected from light, and should not be frozen or shaken. Maintain the cold chain during transport and avoid exposing the solution to temperatures outside the recommended range.

Magneclo is supplied as a sterile solution for injection and can be given either intramuscularly or intravenously. The route, infusion rate, and total volume are determined by the prescriber according to the clinical situation and patient tolerance.

The most serious risks include hypermagnesemia, which can lead to cardiac arrhythmias, respiratory depression, or cardiac arrest, and severe allergic reactions such as anaphylaxis. Continuous monitoring of cardiac function and serum magnesium is essential during therapy.

Magneclo should be avoided in patients with known hypersensitivity to magnesium chloride, severe renal impairment where magnesium clearance is compromised, and in individuals with existing hypermagnesemia. Caution is also advised for patients on medications that potentiate neuromuscular blockade.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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