Product image of Magneclo (Magnesium Chloride Hexahydrate) supplied by GNH India

Magneclo

Active Ingredient:
Magnesium Chloride Hexahydrate
Origin:
EU

Magneclo (Magnesium Chloride Hexahydrate)

Magnesium chloride hexahydrate, the active ingredient in Magneclo, is an electrolyte presented as a solution for injection for intravenous use. It treats magnesium deficiency and related electrolyte disturbances in hospitalized patients.

GNH India supplies Magneclo as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, transplant centres, oncology centres and pharmacies worldwide.

Manufacturer / TM Owner

Laboratoires Sterop

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Indications & Clinical Uses

  • Magneclo, an intravenous magnesium supplement, is used to correct electrolyte imbalances.
  • Magnesium deficiency: restores normal magnesium concentrations in patients with low serum levels.
  • Hypomagnesemia: raises serum magnesium to therapeutic range during acute care.
  • Electrolyte replacement: supports overall electrolyte homeostasis in surgical or critical‑care settings.

How It Works

  • Magnesium chloride hexahydrate dissociates after intravenous administration, releasing magnesium ions that act as essential cofactors for numerous enzymatic reactions, stabilize ATP, modulate calcium channels, and help maintain cellular membrane potential, thereby restoring electrolyte balance and supporting neuromuscular and cardiac function.

Side Effects

Magneclo may be associated with a range of adverse reactions.

Common Side Effects

  • Injection site pain or erythema
  • Transient flushing or warmth
  • Mild hypotension
  • Nausea or headache

Serious or Rare Side Effects

  • Hypermagnesemia leading to cardiac arrhythmia
  • Severe hypotension or cardiovascular collapse
  • Respiratory depression or muscle weakness
  • Anaphylactic or severe allergic reaction

Precautions & Warnings

  • Magneclo requires careful clinical monitoring before and during administration.
  • Renal impairment: monitor serum magnesium and adjust infusion rate.
  • Cardiac disease: use cautiously in patients with conduction abnormalities.
  • Concurrent calcium therapy: assess for additive effects on cardiac conduction.
  • Pregnancy: safety not established; weigh potential benefits against risks.
  • Store at 2-8°C: keep refrigerated, protect from light, do not freeze or shake.

Avoid Interactions

Magneclo can interact with several drug classes; awareness helps prevent adverse events.

Major Interactions (Avoid)

  • Neuromuscular blocking agents: may potentiate blockade.
  • Calcium channel blockers: risk of additive hypotension.
  • Digoxin: increased risk of toxicity.

Moderate Interactions (Monitor Closely)

  • ACE inhibitors or ARBs: monitor renal function and electrolytes.
  • Loop diuretics: may exacerbate magnesium loss.
  • Antacids containing aluminum or magnesium: assess cumulative magnesium load.

Frequently Asked Questions

Magneclo is an intravenous magnesium chloride hexahydrate solution used to treat magnesium deficiency, hypomagnesemia, and to provide electrolyte replacement in patients requiring rapid correction of low magnesium levels, especially in hospital or critical‑care settings.

After IV administration, magnesium chloride hexahydrate releases magnesium ions that serve as cofactors for many enzymatic processes, stabilize ATP, regulate calcium channels, and help maintain normal nerve, muscle, and cardiac function, thereby restoring electrolyte balance.

The dose of Magneclo is determined by the prescribing clinician based on the patient’s serum magnesium level, renal function, and clinical condition. The prescriber sets the infusion rate and total amount required for each individual case.

The pregnancy category for magnesium chloride hexahydrate is unknown. Use in pregnancy or while breastfeeding should only occur when the potential benefit justifies any possible risk, and it must be decided by the treating physician.

To order Magneclo, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including cold‑chain if needed) and import documentation.

Magneclo provides magnesium chloride hexahydrate in a sterile injectable solution, offering rapid bioavailability compared with oral magnesium salts. It is preferred when immediate correction of magnesium levels is required, whereas oral preparations are used for maintenance therapy.

Magneclo should be stored at 2‑8 °C, protected from light, and must not be frozen or shaken. Keep the vial in its original packaging until use and discard any solution that appears discolored or contains particles.

Magneclo is administered intravenously by slow infusion under the supervision of qualified healthcare personnel. The infusion rate and total dose are individualized according to the patient’s clinical status and laboratory results.

Serious risks include hypermagnesemia, which can cause cardiac arrhythmias, severe hypotension, respiratory depression, and in rare cases anaphylactic reactions. Continuous monitoring of vital signs and serum magnesium levels is essential during therapy.

Magneclo should be avoided in patients with known hypersensitivity to magnesium chloride, severe renal failure where magnesium clearance is impaired, and in individuals with existing hypermagnesemia. Clinicians must assess each patient’s suitability before initiating therapy.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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