Product image of Magnence (Magnesium) supplied by GNH India

Magnence

Active Ingredient:
Magnesium
Origin:
EU

Magnence (Magnesium)

Magnesium, the active ingredient in Magnence, is a mineral supplement presented as an oral tablet for oral use. It helps correct magnesium deficiency and supports normal muscle and nerve function, particularly in adults who require supplemental magnesium.

GNH India supplies Magnence as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The product conforms to EU quality standards and is marketed as an over‑the‑counter preparation. Its manufacturing follows Good Manufacturing Practices and includes full traceability of raw materials.

Manufacturer / TM Owner

Kora Corporation Limited

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Indications & Clinical Uses

Magnence is used to address conditions related to low magnesium levels and associated physiological disturbances.

  • Magnesium deficiency: helps restore normal serum magnesium concentrations.
  • Muscle cramps: reduces frequency and intensity of involuntary muscle contractions.
  • Electrolyte imbalance: contributes to overall electrolyte homeostasis, supporting cardiac and neuromuscular stability.

How It Works

  • Magnesium supplied by Magnence dissociates into Mg2+ ions after oral absorption. These ions serve as essential cofactors for more than 300 enzymatic reactions, including ATP synthesis, protein formation, and nucleic acid stability. By participating in calcium channel regulation and sodium‑potassium pump activity, magnesium supports neuromuscular transmission, vascular tone, and electrolyte equilibrium throughout the body.

Side Effects

Oral magnesium supplementation may be associated with a range of adverse reactions, varying from mild to severe.

Common Side Effects

  • Diarrhea: loose stools occurring after intake.
  • Abdominal cramping: discomfort in the stomach region.
  • Nausea: feeling of sickness or urge to vomit.
  • Flatulence: increased intestinal gas.

Serious or Rare Side Effects

  • Hypermagnesemia: elevated blood magnesium leading to cardiac arrhythmias.
  • Hypotension: significant drop in blood pressure.
  • Respiratory depression: slowed breathing in severe cases.
  • Muscle weakness: notable loss of strength.

Precautions & Warnings

When considering Magnence, several safety measures should be observed to minimize risk.

  • Renal function assessment: evaluate kidney performance before initiating therapy.
  • Serum magnesium monitoring: check levels periodically during prolonged use.
  • Concomitant cardiac conditions: use caution in patients with heart block or arrhythmias.
  • Drug interaction awareness: review other medications that may affect magnesium balance.
  • Pregnancy and lactation: consult a healthcare professional before use.
  • Store at ambient temperature: keep below 25 °C in the original container, protect from moisture and direct sunlight.

Avoid Interactions

Magnence can influence the pharmacokinetics or pharmacodynamics of several other medicines.

Major Interactions (Avoid)

  • Tetracycline antibiotics: magnesium chelation markedly reduces antibiotic absorption.
  • Fluoroquinolone antibiotics: concurrent use decreases fluoroquinolone bioavailability.
  • Bisphosphonates: magnesium impairs oral bisphosphonate absorption.

Moderate Interactions (Monitor Closely)

  • ACE inhibitors: additive effect on blood pressure may cause hypotension.
  • Loop and thiazide diuretics: may increase urinary magnesium loss, requiring dose adjustment.
  • Potassium‑sparing diuretics: risk of combined hypermagnesemia.
  • Proton pump inhibitors: long‑term use can lower magnesium stores, necessitating monitoring.

Frequently Asked Questions

Magnence is an oral magnesium supplement indicated for the correction of magnesium deficiency, relief of muscle cramps, and support of electrolyte balance. It is commonly employed when dietary intake is insufficient or when clinical conditions increase magnesium loss.

Magnesium acts as a vital cofactor for hundreds of enzymatic reactions, including those involved in ATP production, protein synthesis, and nucleic acid formation. It also modulates calcium channels, influences nerve impulse transmission, and helps maintain normal muscle contraction and vascular tone.

The appropriate dose of Magnence is determined by the prescribing healthcare professional based on the individual’s age, clinical condition, and laboratory results. Patients should follow the prescriber’s instructions and not adjust the dose without medical guidance.

Safety of magnesium supplementation during pregnancy or lactation should be evaluated by a qualified clinician. While magnesium is an essential nutrient, the prescriber will consider maternal health, fetal development, and any concurrent medications before recommending Magnence.

To request Magnence, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements), and necessary import documentation.

Magnence provides elemental magnesium in a readily absorbable oral form, comparable to other OTC magnesium tablets or capsules. Compared with dietary sources, it offers a precise, controlled dose, and unlike intravenous magnesium, it is convenient for long‑term outpatient use. Choice of product may depend on formulation, tolerability, and specific clinical needs.

Magnence should be stored at ambient temperature, preferably below 25 °C, in its original packaging to protect it from moisture and direct sunlight. Keep the container tightly closed and out of reach of children. No special refrigeration is required.

Magnence is taken orally, usually with a full glass of water. It can be taken with or without food, although taking it with meals may reduce gastrointestinal upset in some individuals. Follow the dosing instructions provided by the prescriber.

The most serious risks include hypermagnesemia, which can cause cardiac arrhythmias, severe hypotension, respiratory depression, and muscle weakness. These events are rare and typically occur in patients with impaired renal function or when excessive doses are taken.

Magnence should be avoided in individuals with severe renal impairment, known hypersensitivity to magnesium, or in patients taking medications that may cause dangerous electrolyte disturbances without medical supervision. Consultation with a healthcare professional is essential before starting therapy.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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