Product image of Magnerot (Magnesium Orotate Dihydrate) supplied by GNH India

Magnerot

Active Ingredient:
Magnesium Orotate Dihydrate
Origin:
EU

Magnerot (Magnesium Orotate Dihydrate)

Magnesium orotate dihydrate, the active ingredient in Magnerot, is a magnesium supplement presented as an oral dosage form for oral use. It is used to address magnesium deficiency and to support cardiovascular and muscle function in adults.
GNH India supplies Magnerot as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Wörwag Pharma Gmbh & Co. Kg

1
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Indications & Clinical Uses

Magnerot is a magnesium supplement that acts on mineral homeostasis and related physiological processes.

  • Magnesium deficiency: helps restore normal magnesium levels in the body.
  • Cardiovascular health: supports normal heart rhythm and vascular tone.
  • Muscle function and relaxation: promotes normal muscle contraction and aids in relieving muscle cramps.

How It Works

  • Magnesium orotate dihydrate dissociates to release magnesium ions, which serve as essential cofactors for numerous enzymatic reactions, including ATP synthesis, protein synthesis, and ion transport. The magnesium ions stabilize cellular membranes, modulate calcium channels, and support neuromuscular transmission, thereby contributing to normal muscle, nerve, and cardiovascular function.

Side Effects

Magnerot is generally well tolerated, but adverse reactions can occur.

Common Side Effects

  • Gastrointestinal upset: nausea, abdominal discomfort, or mild diarrhea.
  • Metallic taste in the mouth.
  • Headache.

Serious or Rare Side Effects

  • Hypermagnesemia: elevated serum magnesium leading to cardiac arrhythmia.
  • Severe hypotension or bradycardia.
  • Allergic reactions: rash, itching, or swelling.
  • Respiratory depression in extreme cases of overdose.

Precautions & Warnings

Before using Magnerot, consider the following precautions.

  • Renal function assessment: impaired kidneys may reduce magnesium clearance.
  • Serum magnesium monitoring: avoid accumulation in patients with existing hypermagnesemia.
  • Cardiovascular caution: use carefully in individuals with heart block or severe arrhythmias.
  • Pregnancy and lactation: safety not established; consult a healthcare professional.
  • Drug interaction review: evaluate concurrent use of other magnesium‑containing products.
  • Store at ambient temperature: keep in the original container, protect from moisture and direct sunlight.

Avoid Interactions

Magnerot may interact with other medicines; awareness of the interaction level is important.

Major Interactions (Avoid)

  • Tetracycline antibiotics: magnesium chelation reduces antibiotic absorption.
  • Fluoroquinolone antibiotics: concurrent use may diminish antibiotic efficacy.
  • Bisphosphonates: magnesium can impair oral bisphosphonate absorption.

Moderate Interactions (Monitor Closely)

  • ACE inhibitors or ARBs: combined effect may increase serum potassium.
  • Digoxin: elevated magnesium may enhance digoxin toxicity.
  • NSAIDs: concurrent use may affect renal magnesium handling.
  • Other magnesium supplements or antacids: risk of excessive magnesium intake.

Frequently Asked Questions

Magnerot is an oral magnesium supplement indicated for the correction of magnesium deficiency, support of normal cardiovascular function, and promotion of healthy muscle contraction and relaxation. It is commonly used in adults who require additional magnesium to maintain physiological balance.

Magnesium orotate dihydrate provides magnesium ions that act as cofactors for many enzymatic reactions, including those involved in ATP production, protein synthesis, and ion transport. These ions help stabilize cell membranes, regulate calcium channels, and support neuromuscular and cardiac function.

The appropriate dose of Magnerot is determined by a qualified prescriber based on the individual’s clinical condition, laboratory values, and overall health status. Patients should follow the dosing instructions provided by their healthcare professional.

The safety of Magnerot in pregnancy and lactation has not been definitively established. Women who are pregnant, planning to become pregnant, or breastfeeding should discuss potential risks and benefits with their healthcare provider before using this product.

To order Magnerot, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India supplies hospitals, pharmacies, and procurement teams worldwide, and will request trade or institutional credentials before providing pricing, availability, shipping details, and any necessary import documentation.

Magnerot delivers magnesium as the orotate salt, which may offer enhanced cellular uptake compared with inorganic salts such as magnesium oxide. While clinical differences are modest, some clinicians prefer orotate for its potential cardioprotective properties, whereas other magnesium forms are chosen for cost or specific gastrointestinal tolerance.

Magnerot should be stored at ambient temperature, below 25 °C, in its original packaging to protect it from moisture and direct sunlight. Keep the container tightly closed and out of reach of children.

Magnerot is taken orally, usually with water. It can be taken with or without food, but patients should follow the prescriber’s guidance regarding timing relative to meals or other medications to optimize absorption.

The most serious risks include hypermagnesemia, which can cause cardiac arrhythmias, severe hypotension, respiratory depression, and in rare cases, allergic reactions such as rash or swelling. Patients with renal impairment are at higher risk and should be monitored closely.

Magnerot should be avoided in individuals with known hypersensitivity to magnesium orotate, those with severe renal failure, existing hypermagnesemia, or significant heart block without medical supervision. Consultation with a healthcare professional is essential before initiating therapy.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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