Product image of Magnesium-Diapsoral 4mmol (Magnesium Sulfate Heptahydrate) supplied by GNH India

Magnesium-Diapsoral 4mmol

Active Ingredient:
Magnesium Sulfate Heptahydrate
Origin:
EU

Magnesium-Diapsoral 4mmol (Magnesium Sulfate Heptahydrate)

Magnesium sulfate heptahydrate, the active ingredient in Magnesium-Diapsoral 4mmol, is an electrolyte solution presented as a 4mmol injectable preparation for intramuscular and intravenous use. It helps restore magnesium levels in patients with deficiency or specific clinical conditions requiring magnesium supplementation.

GNH India supplies Magnesium-Diapsoral 4mmol as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals worldwide.

Manufacturer / TM Owner

Protina Pharmazeutische Gesellschaft Mbh

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

Magnesium sulfate is employed in several clinical situations that involve magnesium deficiency or the need for magnesium’s physiological effects.

  • Severe hypomagnesemia: restores serum magnesium concentrations.
  • Preeclampsia/eclampsia: prevents and treats seizures in pregnant women.
  • Torsades de pointes: stabilises cardiac rhythm in polymorphic ventricular tachycardia.
  • Tocolysis (preterm labor): relaxes uterine smooth muscle to delay premature contractions.

How It Works

  • Magnesium sulfate provides magnesium ions that act as a physiological calcium antagonist, modulating voltage‑gated calcium channels, stabilising neuronal membranes, and serving as a co‑factor for ATP‑dependent enzymes. These actions reduce neuromuscular excitability, promote vasodilation, and help normalize cardiac electrophysiology, thereby correcting magnesium deficiency and exerting therapeutic effects in the indicated conditions.

Side Effects

Adverse reactions may occur with magnesium sulfate administration.

Common Side Effects

  • Flushing or warmth at the injection site
  • Nausea or vomiting
  • Headache
  • Hypotension
  • Sweating
  • Dizziness

Serious or Rare Side Effects

  • Respiratory depression or arrest
  • Severe hypotension or cardiovascular collapse
  • Hypermagnesemia leading to cardiac arrhythmias
  • Neuromuscular blockade causing muscle weakness
  • Anaphylactic or severe allergic reactions
  • Cardiac arrest

Precautions & Warnings

Magnesium sulfate should be used with careful clinical assessment and monitoring.

  • Renal impairment: monitor serum magnesium and adjust dose.
  • Cardiac disease: use cautiously due to potential hypotensive effects.
  • Pregnancy: assess risk‑benefit, especially in preeclampsia management.
  • Concomitant neuromuscular blockers: monitor for enhanced paralysis.
  • Electrolyte imbalance: correct concurrent abnormalities before use.
  • Store at 2-8°C: keep refrigerated, protect from light, do not freeze.

Avoid Interactions

Magnesium sulfate can interact with several medications, requiring attention to avoid adverse outcomes.

Major Interactions (Avoid)

  • Calcium channel blockers: additive hypotensive effect.
  • Neuromuscular blocking agents: prolonged paralysis.
  • Other magnesium‑containing products: risk of hypermagnesemia.

Moderate Interactions (Monitor Closely)

  • Loop diuretics: increase renal magnesium loss.
  • ACE inhibitors or ARBs: alter renal handling of magnesium.
  • Aminoglycoside antibiotics: may potentiate neuromuscular blockade.

Frequently Asked Questions

Magnesium-Diapsoral 4mmol provides magnesium sulfate heptahydrate for intravenous or intramuscular administration. It is used to correct severe magnesium deficiency, prevent seizures in preeclampsia/eclampsia, manage certain cardiac arrhythmias such as torsades de pointes, and as a tocolytic to delay premature labor.

Magnesium sulfate supplies magnesium ions that act as a calcium antagonist, stabilising neuronal and cardiac membranes, reducing neuromuscular excitability, and supporting ATP‑dependent enzymatic processes. These actions help normalize electrolyte balance, lower seizure risk, and stabilize cardiac rhythm.

The specific dose and infusion rate are determined by the prescribing clinician based on the patient’s condition, weight, renal function, and serum magnesium levels. Healthcare professionals should follow local guidelines and adjust dosing as needed.

Magnesium sulfate is commonly used in pregnancy for preeclampsia and eclampsia management, but the decision to use it should be made by a qualified obstetrician who weighs maternal benefits against potential fetal risks. Limited data are available for breastfeeding, so clinicians should consider the risk‑benefit profile.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including cold‑chain if needed), and import documentation.

Magnesium-Diapsoral 4mmol delivers magnesium sulfate heptahydrate in a standardized 4mmol concentration, suitable for both IV and IM routes. Compared with oral magnesium salts, it offers rapid serum level correction and precise dosing, which is essential in acute settings such as severe hypomagnesemia or obstetric emergencies.

The product should be stored at 2‑8 °C, protected from light, and kept in its original container. Do not freeze or shake the vial. Before administration, allow the solution to reach room temperature if required, and inspect for particulate matter or discoloration.

Magnesium-Diapsoral is administered by a qualified healthcare professional either intravenously as a slow infusion or intramuscularly as a deep injection, following aseptic technique. The infusion rate and volume are adjusted according to the clinical indication and patient monitoring parameters.

Serious risks include hypermagnesemia, which can cause respiratory depression, cardiac arrest, severe hypotension, and neuromuscular blockade. Patients with renal failure or those receiving other magnesium‑containing agents are at higher risk and require close monitoring of serum magnesium levels.

Magnesium-Diapsoral should be avoided in patients with known hypersensitivity to magnesium sulfate, severe renal impairment without appropriate monitoring, and in those with existing hypermagnesemia. Caution is also advised for individuals on concurrent neuromuscular blockers or high‑dose calcium channel blockers.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.