Product image of Magnesium-Diasporal Protina Pharmazeutische Gmbh (Magnesium Citrate) supplied by GNH India

Magnesium-Diasporal Protina Pharmazeutische Gmbh

Active Ingredient:
Magnesium Citrate
Origin:
EU

Magnesium-Diasporal Protina Pharmazeutische Gmbh (Magnesium Citrate)

Magnesium citrate, the active ingredient in Magnesium-Diasporal, is a magnesium supplement presented as an oral formulation for oral use. It helps address low magnesium levels and supports normal neuromuscular and cardiovascular function in patients with identified deficiency. Magnesium-Diasporal is marketed as an over‑the‑counter product intended for adults who require supplemental magnesium.

GNH India supplies Magnesium-Diasporal as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Protina Pharmazeutische Gesellschaft Mbh

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Indications & Clinical Uses

Magnesium-Diasporal (magnesium citrate) is used to correct low magnesium states and support related physiological processes.

  • Magnesium deficiency: restores normal serum magnesium concentrations.
  • Hypomagnesemia: aids in the rapid correction of clinically significant magnesium loss.
  • Electrolyte imbalance: contributes to overall electrolyte homeostasis when magnesium is deficient.

How It Works

  • Magnesium citrate dissociates in the gastrointestinal tract, releasing magnesium ions that serve as essential cofactors for numerous enzymatic reactions, including ATP synthesis, protein formation, and nucleic acid stability. The ions modulate calcium channel activity, support neuromuscular transmission, and help maintain normal cardiac rhythm and vascular tone.

Side Effects

Magnesium-Diasporal may cause a range of adverse reactions, most of which are mild and transient.

Common Side Effects

  • Diarrhea: loose stools occurring after oral intake.
  • Abdominal discomfort: cramping or pain in the stomach area.
  • Nausea: feeling of queasiness.
  • Flatulence: increased intestinal gas.
  • Taste alteration: metallic or unusual mouthfeel.
  • Headache: mild to moderate head pain.

Serious or Rare Side Effects

  • Hypermagnesemia: excessively high serum magnesium levels, potentially leading to cardiac arrhythmia.
  • Severe allergic reaction: rash, itching, swelling, or difficulty breathing.
  • Low blood pressure: marked hypotension, especially in patients with cardiac disease.
  • Muscle weakness: notable reduction in muscle strength.
  • Respiratory depression: slowed breathing in extreme cases.
  • Cardiac conduction abnormalities: disturbances in heart rhythm.

Precautions & Warnings

When using Magnesium-Diasporal, consider the following safety measures.

  • Renal function assessment: evaluate kidney performance before initiating therapy.
  • Serum magnesium monitoring: check levels periodically to avoid excess.
  • Cardiac condition caution: use carefully in patients with heart block or arrhythmias.
  • Hypermagnesemia avoidance: do not administer if serum magnesium is already elevated.
  • Elderly dose adjustment: consider lower doses for older adults due to altered metabolism.
  • Store at ambient temperature: keep in the original pack, protect from moisture and direct sunlight.

Avoid Interactions

Magnesium-Diasporal can affect the absorption or activity of several medicines.

Major Interactions (Avoid)

  • Tetracycline antibiotics: reduced absorption when taken concurrently.
  • Fluoroquinolone antibiotics: decreased efficacy due to chelation.
  • Bisphosphonates: impaired gastrointestinal uptake.
  • Digoxin: potential increase in serum levels.
  • Calcium channel blockers: additive effect on cardiac conduction.

Moderate Interactions (Monitor Closely)

  • ACE inhibitors: enhanced risk of hyperkalemia.
  • Loop diuretics: may increase magnesium loss, requiring dose adjustment.
  • Proton pump inhibitors: possible reduction in magnesium absorption over long term.
  • NSAIDs: combined effect on renal function.
  • Anticoagulants (warfarin): potential alteration of INR values.

Frequently Asked Questions

Magnesium-Diasporal contains magnesium citrate and is used to treat magnesium deficiency and hypomagnesemia. It helps restore normal magnesium levels, supporting muscle function, nerve transmission, and cardiovascular health in patients who have low serum magnesium.

After oral ingestion, magnesium citrate dissociates, releasing magnesium ions that act as cofactors for many enzymatic reactions. These ions aid ATP production, regulate calcium channels, and maintain neuromuscular and cardiac function, thereby correcting the biochemical deficits caused by low magnesium.

The appropriate dose of Magnesium-Diasporal is determined by the prescribing healthcare professional based on the patient’s serum magnesium level, age, renal function, and overall clinical condition. Dosage instructions should always follow the prescriber’s recommendation.

Safety data for magnesium citrate in pregnancy and lactation are limited. Healthcare providers should evaluate the risk‑benefit ratio before prescribing it to pregnant or nursing women, and use only if clearly needed.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Magnesium-Diasporal provides magnesium in the citrate salt form, which is generally well‑absorbed compared with oxide or carbonate salts. It offers a balance of bioavailability and tolerability, making it suitable for patients needing reliable magnesium repletion without excessive gastrointestinal upset.

Store Magnesium-Diasporal at ambient temperature, below 25 °C. Keep the product in its original container, protect it from moisture, direct sunlight and extreme heat to maintain potency and stability.

Magnesium-Diasporal is taken orally, usually with a glass of water. It may be taken with or without food, but patients should follow the prescriber’s guidance regarding timing relative to meals or other medications.

The most serious risks include hypermagnesemia, which can cause cardiac arrhythmias, severe hypotension, respiratory depression, and in rare cases, life‑threatening cardiac conduction disturbances. Prompt medical attention is required if symptoms of excess magnesium appear.

Magnesium-Diasporal should be avoided in individuals with known hypersensitivity to magnesium citrate, severe renal impairment, existing hypermagnesemia, or those taking medications that may cause dangerous electrolyte imbalances without medical supervision.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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