Product image of Magnesium Sulfate Demo (Magnesium Sulfate Heptahydrate) supplied by GNH India

Magnesium Sulfate Demo

Active Ingredient:
Magnesium Sulfate Heptahydrate
Origin:
EU

Magnesium Sulfate Demo (Magnesium Sulfate Heptahydrate)

Magnesium sulfate, the active ingredient in Magnesium Sulfate Demo, is an electrolyte/mineral supplement presented as a sterile solution for intramuscular and intravenous use. It is employed to treat magnesium deficiency, prevent seizures in eclampsia and pre‑eclampsia, and act as a tocolytic in obstetric care.

GNH India supplies Magnesium Sulfate Demo as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals worldwide.

Manufacturer / TM Owner

Demo Abee

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

Magnesium sulfate is an electrolyte/mineral supplement used in several obstetric, cardiac and respiratory conditions.

  • Eclampsia: prevents seizures in pregnant women with this life‑threatening condition.
  • Pre‑eclampsia: reduces the risk of progression to eclampsia by stabilising neuronal excitability.
  • Magnesium deficiency: restores normal serum magnesium levels and supports muscle and nerve function.
  • Torsades de pointes: shortens QT interval and helps terminate this ventricular arrhythmia.
  • Severe asthma exacerbations: provides bronchodilation and reduces airway hyper‑responsiveness.
  • Tocolysis: relaxes uterine smooth muscle to delay premature labor.

How It Works

  • Magnesium sulfate dissociates to release Mg2+ ions that competitively antagonise calcium at voltage‑gated channels, stabilising neuronal membranes, decreasing acetylcholine release, and producing vasodilation. The resulting reduction in calcium‑mediated excitability underlies its anticonvulsant, tocolytic and anti‑arrhythmic actions.

Side Effects

Adverse reactions may range from mild to life‑threatening and should be monitored during therapy.

Common Side Effects

  • Flushing or warmth sensation
  • Sweating
  • Nausea or vomiting
  • Headache
  • Feeling of weakness or fatigue
  • Transient hypotension

Serious or Rare Side Effects

  • Respiratory depression or arrest
  • Cardiac arrhythmias, including bradycardia
  • Severe hypotension
  • Loss of deep tendon reflexes
  • Anaphylactic reaction
  • Hypermagnesemia leading to neuromuscular blockade

Precautions & Warnings

Magnesium sulfate requires careful monitoring and specific clinical considerations.

  • Serum magnesium monitoring: adjust infusion rate to maintain therapeutic range.
  • Renal impairment: reduce dose or increase interval due to reduced clearance.
  • Myasthenia gravis: avoid because it may exacerbate muscle weakness.
  • Concurrent neuromuscular blockers: use with caution to prevent additive paralysis.
  • Calcium level assessment: correct hypocalcaemia before initiating therapy.
  • Store at 2-8°C: keep refrigerated, protect from light, do not freeze or shake.

Avoid Interactions

Magnesium sulfate can interact with several drug classes, necessitating vigilance.

Major Interactions (Avoid)

  • Calcium channel blockers: additive vasodilatory effect may cause profound hypotension.
  • Neuromuscular blocking agents: potentiates muscle relaxation and risk of respiratory failure.
  • Aminoglycoside antibiotics: increased risk of neuromuscular blockade.
  • Loop diuretics: may enhance magnesium loss, complicating therapeutic monitoring.
  • Other magnesium‑containing products: risk of hypermagnesemia.

Moderate Interactions (Monitor Closely)

  • ACE inhibitors: may augment hypotensive response.
  • Beta‑blockers: combined effect on heart rate and blood pressure.
  • NSAIDs: can affect renal handling of magnesium.
  • Warfarin: rare reports of altered anticoagulation.
  • Antacids containing magnesium: monitor total magnesium load.

Frequently Asked Questions

Magnesium Sulfate Demo is used to treat magnesium deficiency, prevent seizures in eclampsia and pre‑eclampsia, act as a tocolytic to delay premature labor, manage torsades de pointes ventricular arrhythmia, and provide bronchodilation in severe asthma exacerbations.

Magnesium sulfate releases magnesium ions that act as calcium antagonists at voltage‑gated channels, stabilising neuronal membranes, reducing neurotransmitter release, and causing vasodilation. This mechanism underlies its anticonvulsant, tocolytic, anti‑arrhythmic and bronchodilatory effects.

The dosage of magnesium sulfate is determined by the prescribing clinician based on the specific indication, patient weight, renal function and serum magnesium levels. Healthcare professionals set the infusion rate or injection amount according to established clinical guidelines.

Magnesium sulfate is classified as pregnancy category unknown, but it is routinely used in obstetric practice for eclampsia, pre‑eclampsia and tocolysis under strict medical supervision. Limited data exist for breastfeeding, and clinicians weigh potential benefits against risks.

To order, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including cold‑chain if needed) and required import documentation.

Unlike traditional anticonvulsants that target GABA or sodium channels, magnesium sulfate works by calcium antagonism and membrane stabilisation. It is particularly valuable in pregnancy‑related seizures where many other anticonvulsants pose fetal risks, offering a rapid, reversible effect with a well‑known safety profile when monitored.

Magnesium sulfate for injection should be stored at 2‑8 °C, kept refrigerated, protected from light, and never frozen or shaken. Use aseptic technique during preparation, and discard any solution that appears discoloured or contains particles.

Magnesium sulfate is administered by intramuscular or intravenous injection. The route, concentration and infusion rate are selected by the prescriber, with continuous cardiac and respiratory monitoring recommended during intravenous administration.

The most serious risks include respiratory depression, loss of deep tendon reflexes, severe hypotension, cardiac arrhythmias and hypermagnesemia. Prompt recognition of these signs and immediate cessation of the infusion, followed by calcium gluconate administration, are essential.

Magnesium sulfate is contraindicated in patients with known hypersensitivity to magnesium salts, severe renal impairment that cannot be managed, myasthenia gravis, and in those receiving high doses of other magnesium‑containing products without careful monitoring.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Related Products

Other formulations containing Magnesium Sulfate Heptahydrate

A

A
A

A
A

A
A

A

Browse all products →

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Regulatory recognitions

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.

SGS GSDP Certification

GSDP Compliant from SGS

URS ISO 9001

URS ISO 9001 Certification

FDA Maharashtra

Licensed by FDA Maharashtra

IEC License DGFT

IEC License issued by DGFT