Product image of Magnesium Sulfate Heptahydrate Ibe (Magnesium Sulfate Heptahydrate) supplied by GNH India

Magnesium Sulfate Heptahydrate Ibe

Active Ingredient:
Magnesium Sulfate Heptahydrate
Origin:
EU

Magnesium Sulfate Heptahydrate Ibe (Magnesium Sulfate Heptahydrate)

Magnesium sulfate heptahydrate, the active ingredient in Magnesium Sulfate Heptahydrate Ibe, is a magnesium salt presented as a sterile injectable solution for intramuscular and intravenous use. It is employed to prevent and treat eclampsia, correct magnesium deficiency, and manage certain cardiac arrhythmias.

GNH India supplies Magnesium Sulfate Heptahydrate Ibe as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals worldwide.

Manufacturer / TM Owner

Ibe Pharma

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

Magnesium sulfate heptahydrate acts on electrolyte balance and neuromuscular transmission, making it useful in several acute clinical settings.

  • Eclampsia and severe pre‑eclampsia: prevents seizures and stabilises maternal blood pressure during pregnancy.
  • Magnesium deficiency: restores normal serum magnesium levels in patients with low magnesium.
  • Ventricular arrhythmias (e.g., torsades de pointes): reduces the duration and frequency of life‑threatening heart rhythm disturbances.
  • Severe asthma exacerbations: provides adjunct bronchodilation and reduces airway hyper‑responsiveness.

How It Works

  • Magnesium sulfate heptahydrate dissociates to release Mg2+ ions that compete with calcium at voltage‑gated channels, stabilising neuronal membranes, decreasing acetylcholine release, and promoting vasodilation. The calcium‑antagonist effect dampens excitatory neurotransmission, while the vasodilatory action lowers systemic vascular resistance, contributing to seizure prophylaxis and arrhythmia control.

Side Effects

Adverse reactions may vary with dose, infusion rate, and patient comorbidities.

Common Side Effects

  • Flushing or feeling of warmth
  • Sweating
  • Nausea or vomiting
  • Headache
  • Mild hypotension
  • Dizziness

Serious or Rare Side Effects

  • Severe hypotension or cardiovascular collapse
  • Respiratory depression or apnea
  • Cardiac arrest
  • Hypermagnesemia with neuromuscular weakness
  • Allergic reactions including anaphylaxis
  • Prolonged neuromuscular blockade

Precautions & Warnings

Magnesium sulfate should be used with careful clinical monitoring and appropriate laboratory testing.

  • Renal impairment: avoid or adjust dose, as reduced clearance can lead to accumulation.
  • Neuromuscular disease (e.g., myasthenia gravis): monitor for exaggerated muscle weakness.
  • Cardiac disease: observe blood pressure and heart rhythm continuously.
  • Pregnancy: reserve for situations where maternal benefit outweighs fetal risk.
  • Concomitant medications: review for agents that affect magnesium levels or neuromuscular transmission.
  • Store at ambient temperature: keep in original container, protect from moisture and direct light.

Avoid Interactions

Magnesium sulfate can alter the effects of several drug classes, requiring vigilance.

Major Interactions (Avoid)

  • Calcium channel blockers: additive hypotensive effect may be dangerous.
  • Neuromuscular blocking agents: prolonged paralysis and respiratory compromise.
  • Other magnesium‑containing products: risk of hypermagnesemia.

Moderate Interactions (Monitor Closely)

  • ACE inhibitors or ARBs: may enhance blood pressure lowering.
  • Loop diuretics: can affect renal magnesium handling and serum levels.
  • Aminoglycoside antibiotics: increased risk of neuromuscular toxicity.

Frequently Asked Questions

Magnesium Sulfate Heptahydrate Ibe is used to prevent and treat eclampsia and severe pre‑eclampsia in pregnancy, to correct magnesium deficiency, to manage certain ventricular arrhythmias such as torsades de pointes, and as an adjunct in severe asthma exacerbations.

The drug releases magnesium ions that act as calcium antagonists, stabilising cell membranes, reducing neuronal excitability, promoting vasodilation, and exerting anticonvulsant effects. These actions help control seizures, normalize heart rhythm, and relax bronchial smooth muscle.

The prescribed dose and infusion rate are determined by the treating clinician based on the specific indication, patient weight, renal function, and clinical response. Healthcare professionals should follow local guidelines and monitor serum magnesium levels during therapy.

Magnesium sulfate is classified as a pregnancy‑category drug that may be used when the expected maternal benefit outweighs potential fetal risk. It is commonly employed for eclampsia prevention. Limited data exist for breastfeeding, so clinicians should assess risk versus benefit.

Enquiries are submitted via the product page at gnhindia.com where you specify the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain needs), and import documentation.

Compared with other anticonvulsants, magnesium sulfate uniquely provides both seizure prophylaxis and electrolyte replacement. Unlike calcium channel blockers, it directly antagonises calcium at the cellular level, offering rapid vasodilation. Its dual role makes it the preferred agent for eclampsia and certain arrhythmias.

Magnesium Sulfate Heptahydrate Ibe should be stored at ambient temperature, below 25 °C, in its original sealed container. Protect it from moisture, direct sunlight, and extreme temperature fluctuations to maintain sterility and potency.

The product is supplied as a sterile injectable solution for intramuscular or intravenous administration. It is typically given as a controlled infusion or bolus under continuous cardiac and blood pressure monitoring, following the prescriber's dosing instructions.

Serious risks include severe hypotension, respiratory depression, cardiac arrest, hypermagnesemia leading to neuromuscular weakness, and rare allergic reactions. Prompt monitoring of vital signs and serum magnesium levels helps mitigate these hazards.

Patients with significant renal failure, uncontrolled heart block, severe myasthenia gravis, or known hypersensitivity to magnesium salts should generally avoid this medication, unless a specialist determines that benefits outweigh the risks.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Related Products

Other formulations containing Magnesium Sulfate Heptahydrate

A

A
A

A
A

A
A

A

Browse all products →

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Regulatory recognitions

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.

SGS GSDP Certification

GSDP Compliant from SGS

URS ISO 9001

URS ISO 9001 Certification

FDA Maharashtra

Licensed by FDA Maharashtra

IEC License DGFT

IEC License issued by DGFT