Product image of Magnesium Sulfate Macarthys Laboratories (Magnesium Sulfate Heptahydrate) supplied by GNH India

Magnesium Sulfate Macarthys Laboratories

Active Ingredient:
Magnesium Sulfate Heptahydrate
Origin:
EU

Magnesium Sulfate Macarthys Laboratories (Magnesium Sulfate Heptahydrate)

Magnesium sulfate, the active ingredient in Magnesium Sulfate Macarthys Laboratories, is an electrolyte supplement presented as an intravenous solution for intravenous use. It is employed to correct severe magnesium deficiency and to manage conditions such as eclampsia, torsades de pointes, and other electrolyte disturbances.

GNH India supplies Magnesium Sulfate Macarthys Laboratories as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, transplant centres, oncology centres, pharmacies and clinics worldwide. The company adheres to stringent quality standards and provides regulatory documentation to support safe clinical use.

Manufacturer / TM Owner

Macarthys Laboratories Ltd

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

Magnesium sulfate is used to treat electrolyte disturbances and related obstetric and cardiac conditions.

  • Severe hypomagnesemia: restores serum magnesium levels to prevent neuromuscular and cardiac complications.
  • Prevention and treatment of eclampsia: stabilises maternal magnesium status and reduces seizure risk.
  • Torsades de pointes: provides magnesium ions that help terminate this ventricular arrhythmia.
  • General magnesium deficiency: replenishes body stores in patients with inadequate intake or increased loss.

How It Works

  • Magnesium sulfate dissociates to release magnesium ions that act as a calcium antagonist, promoting vasodilation, stabilising neuronal membranes, and exerting anticonvulsant effects. The ions compete with calcium at voltage‑gated channels, reduce excitatory neurotransmission, and help restore normal serum magnesium concentrations, thereby supporting cardiac, neuromuscular and vascular function.

Side Effects

Adverse reactions may occur with intravenous magnesium administration.

Common Side Effects

  • Flushing or feeling of warmth.
  • Sweating.
  • Nausea or vomiting.
  • Headache.
  • Hypotension.
  • Injection site irritation.

Serious or Rare Side Effects

  • Respiratory depression or arrest.
  • Severe hypotension leading to shock.
  • Cardiac arrhythmias, including bradycardia.
  • Hypermagnesemia with neuromuscular weakness.
  • Anaphylactic or severe allergic reactions.
  • Calcium precipitation causing local tissue injury.

Precautions & Warnings

Magnesium sulfate requires careful monitoring in several clinical situations.

  • Renal impairment: monitor serum magnesium and adjust dose.
  • Cardiac disease: use cautiously due to potential vasodilatory effects.
  • Neuromuscular disorders: observe for increased muscle weakness.
  • Pregnancy: assess risk‑benefit before use.
  • Drug compatibility: avoid mixing with calcium‑containing solutions.
  • Store at 2-8°C: keep refrigerated, protect from light, do not freeze.

Avoid Interactions

Magnesium sulfate can interact with several medications, requiring attention to avoid adverse outcomes.

Major Interactions (Avoid)

  • Calcium salts: risk of insoluble precipitate formation.
  • Neuromuscular blocking agents: enhanced blockade leading to prolonged paralysis.
  • Potassium‑sparing diuretics: increased risk of hypermagnesemia.

Moderate Interactions (Monitor Closely)

  • Aminoglycoside antibiotics: may increase nephrotoxicity.
  • Loop diuretics: can augment magnesium loss.
  • ACE inhibitors or ARBs: may affect renal handling of magnesium.

Frequently Asked Questions

Magnesium Sulfate is an electrolyte supplement administered intravenously to correct severe magnesium deficiency, prevent and treat eclampsia in pregnant patients, manage torsades de pointes ventricular arrhythmia, and address other conditions where serum magnesium levels are critically low.

After infusion, magnesium sulfate releases magnesium ions that act as calcium antagonists, causing vasodilation, stabilising neuronal membranes, and providing anticonvulsant effects. These actions help restore normal magnesium concentrations, supporting cardiac rhythm, neuromuscular function, and vascular tone.

The specific dose of magnesium sulfate is determined by the prescribing clinician based on the patient’s clinical condition, serum magnesium level, weight, and renal function. Dosing regimens vary for hypomagnesemia, eclampsia prophylaxis, and arrhythmia treatment.

Magnesium sulfate is commonly used in obstetric care for eclampsia prevention and treatment, and it is considered relatively safe when administered under medical supervision. However, the risk‑benefit profile should be evaluated by the treating physician, and breastfeeding mothers should discuss use with their healthcare provider.

To place an order, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including cold‑chain where applicable) and necessary import documentation.

Magnesium sulfate is the preferred intravenous source of magnesium because it provides rapid correction of serum levels and has well‑characterised pharmacodynamics. Other electrolytes such as calcium gluconate or potassium chloride address different deficiencies; magnesium sulfate uniquely offers vasodilatory and anticonvulsant properties useful in eclampsia and certain arrhythmias.

Magnesium sulfate for injection should be stored at 2‑8 °C, kept in its original container, protected from light, and must not be frozen or shaken vigorously. If a temperature excursion occurs, inspect the solution for precipitation before use.

Magnesium sulfate is administered intravenously by a qualified healthcare professional. It can be given as a slow infusion or bolus, depending on the indication and clinical protocol. Proper aseptic technique and appropriate infusion equipment are required to ensure safe delivery.

Serious risks include respiratory depression, severe hypotension, cardiac arrhythmias, hypermagnesemia leading to neuromuscular weakness, and rare anaphylactic reactions. Continuous monitoring of vital signs and serum magnesium levels is essential, especially in patients with renal impairment or cardiac disease.

Magnesium sulfate is contraindicated in patients with known hypersensitivity to the product, severe renal failure where magnesium clearance is markedly reduced, and in those receiving incompatible calcium‑containing solutions that could precipitate. Clinicians should also exercise caution in patients with existing heart block or profound hypotension.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.