Product image of Magnesium Sulfate Synchrony Pharma (Magnesium Sulfate Heptahydrate) supplied by GNH India

Magnesium Sulfate Synchrony Pharma

Active Ingredient:
Magnesium Sulfate Heptahydrate
Origin:
EU

Magnesium Sulfate Synchrony Pharma (Magnesium Sulfate Heptahydrate)

Magnesium sulfate, the active ingredient in Magnesium Sulfate Synchrony Pharma, is an electrolyte supplement presented as an injectable solution for intravenous use. It is employed to prevent and treat eclampsia and severe preeclampsia, to correct magnesium deficiency, and to manage certain cardiac arrhythmias.

GNH India supplies Magnesium Sulfate Synchrony Pharma as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to stringent quality standards and provides regulatory documentation for worldwide distribution to meet local regulatory requirements.

Manufacturer / TM Owner

Synchrony Pharma Limited

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

Magnesium sulfate is used in obstetric, cardiac and electrolyte disorders.

  • Eclampsia and severe preeclampsia: prevents seizures and reduces maternal hypertension.
  • Magnesium deficiency: restores normal serum magnesium concentrations.
  • Torsades de pointes: stabilises cardiac repolarisation and terminates ventricular tachycardia.
  • Severe asthma (adjunct): promotes bronchodilation and improves response to standard therapy.

How It Works

  • Magnesium sulfate acts as a calcium antagonist and NMDA‑receptor blocker, reducing calcium influx into neurons and cardiac cells. This stabilises neuronal membranes, diminishes neuromuscular excitability, and produces vasodilatory and anti‑arrhythmic effects that underlie its anticonvulsant and electrolyte‑replenishing actions.

Side Effects

Magnesium sulfate may cause a range of adverse reactions.

Common Side Effects

  • Flushing or feeling of warmth.
  • Nausea or vomiting.
  • Headache.
  • Hypotension.
  • Muscle weakness or fatigue.

Serious or Rare Side Effects

  • Respiratory depression or arrest.
  • Severe hypotension or cardiac arrest.
  • Hypermagnesemia with neuromuscular blockade.
  • Allergic reactions including anaphylaxis.
  • Tissue necrosis at the injection site.

Precautions & Warnings

Magnesium sulfate requires careful monitoring in several clinical situations.

  • Renal impairment: monitor serum magnesium and adjust dose.
  • Myasthenia gravis: may exacerbate muscle weakness.
  • Cardiac conduction disorders: use cautiously and observe ECG.
  • Pregnancy: category unknown; weigh maternal benefits against potential fetal risk.
  • Drug interactions: avoid concurrent calcium‑channel blockers or other magnesium‑containing products.
  • Store below 25°C: keep in original container, protect from light and moisture.

Avoid Interactions

Magnesium sulfate can interact with several medicines, altering its safety profile.

Major Interactions (Avoid)

  • Calcium channel blockers: additive hypotensive effect.
  • Neuromuscular blocking agents: prolonged paralysis.
  • Other magnesium‑containing products: risk of hypermagnesemia.

Moderate Interactions (Monitor Closely)

  • Loop diuretics: increased renal magnesium loss.
  • Aminoglycosides: enhanced neuromuscular blockade.
  • β‑agonists: may reduce magnesium’s therapeutic efficacy.

Frequently Asked Questions

Magnesium Sulfate Synchrony Pharma is an injectable electrolyte supplement used primarily to prevent and treat seizures in eclampsia and severe preeclampsia, to correct magnesium deficiency, and to manage specific cardiac arrhythmias such as torsades de pointes.

Magnesium sulfate acts as a calcium antagonist and blocks NMDA receptors, which stabilises neuronal membranes, reduces neuromuscular excitability, and causes vasodilation. These actions help control seizures, support cardiac electrical stability, and replenish depleted magnesium stores.

The dosage of magnesium sulfate is determined by the prescribing clinician based on the specific indication, patient weight, renal function and clinical response. Healthcare professionals calculate the appropriate infusion rate and total amount according to established guidelines.

Pregnancy safety is classified as unknown for this product. It may be used when the potential maternal benefit outweighs any possible fetal risk, and decisions should be made by a qualified obstetric provider. Limited data are available for breastfeeding, so clinical judgment is required.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including cold‑chain if needed) and import documentation.

Compared with other anticonvulsants, magnesium sulfate uniquely combines seizure control with electrolyte replenishment and vasodilatory effects. Unlike calcium‑based agents, it does not increase calcium load, and its rapid onset via intravenous infusion makes it suitable for acute obstetric emergencies.

Magnesium Sulfate Synchrony Pharma should be stored below 25 °C, in its original packaging, protected from light and moisture. Do not freeze the solution, and keep the vial sealed until ready for use to maintain sterility.

The product is supplied as a sterile injectable solution for intravenous administration. It is typically given as a controlled infusion under continuous clinical monitoring, with dosage adjustments based on serum magnesium levels and patient response.

Serious risks include respiratory depression, severe hypotension, cardiac arrest, hypermagnesemia leading to neuromuscular blockade, and rare allergic reactions such as anaphylaxis. Prompt recognition and supportive measures are essential if these events occur.

Magnesium sulfate is contraindicated in patients with known hypersensitivity to magnesium salts, severe renal failure where clearance is impaired, and in individuals with existing severe hypotension or advanced heart block unless closely monitored in a critical care setting.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Related Products

Other formulations containing Magnesium Sulfate Heptahydrate

A

A
A

A
A

A
A

A

Browse all products →

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Regulatory recognitions

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.

SGS GSDP Certification

GSDP Compliant from SGS

URS ISO 9001

URS ISO 9001 Certification

FDA Maharashtra

Licensed by FDA Maharashtra

IEC License DGFT

IEC License issued by DGFT