Product image of Magnesium Sulfuricum Bbp (Magnesium Sulfate Heptahydrate) supplied by GNH India

Magnesium Sulfuricum Bbp

Active Ingredient:
Magnesium Sulfate Heptahydrate
Origin:
EU

Magnesium Sulfuricum Bbp (Magnesium Sulfate Heptahydrate)

Magnesium sulfate heptahydrate, the active ingredient in Magnesium Sulfuricum Bbp, is a magnesium salt presented as a sterile injectable solution for intramuscular, intravenous, and subcutaneous use. It provides magnesium ions to correct magnesium deficiency and is employed in the management of conditions such as hypomagnesemia, eclampsia, and torsades de pointes in adult patients.

GNH India supplies Magnesium Sulfuricum Bbp as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics across multiple continents worldwide, with adherence to stringent quality standards.

Manufacturer / TM Owner

Bb Pharma A.S.

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Indications & Clinical Uses

Magnesium Sulfuricum Bbp is used to treat electrolyte disturbances and related clinical conditions where magnesium repletion is required.

  • Hypomagnesemia: restores serum magnesium levels to prevent neuromuscular and cardiac complications.
  • Magnesium deficiency: replenishes intracellular magnesium to support enzymatic functions.
  • Eclampsia: provides magnesium to reduce seizure risk in pregnant patients.
  • Torsades de pointes: stabilizes cardiac repolarization by correcting magnesium deficit.

How It Works

  • Magnesium sulfate heptahydrate dissociates to release magnesium ions, which act as essential cofactors for numerous enzymatic reactions, stabilize cell membranes, and antagonize calcium‑mediated excitability. By increasing extracellular magnesium concentration, it counteracts calcium influx, modulates vascular tone, and supports myocardial electrical stability, thereby correcting magnesium deficiency and its physiological consequences.

Side Effects

Adverse reactions may occur with magnesium sulfate administration.

Common Side Effects

  • Injection site pain or irritation.
  • Flushing or warmth sensation.
  • Nausea or mild gastrointestinal upset.
  • Headache.
  • Dizziness or light‑headedness.
  • Transient hypotension.

Serious or Rare Side Effects

  • Hypermagnesemia leading to respiratory depression.
  • Severe hypotension or cardiovascular collapse.
  • Cardiac arrest or severe arrhythmias.
  • Anaphylactic or severe allergic reactions.
  • Muscle weakness progressing to paralysis.
  • Loss of deep tendon reflexes.

Precautions & Warnings

Use of Magnesium Sulfuricum Bbp requires careful clinical assessment.

  • Renal impairment: monitor serum magnesium and adjust dosing.
  • Cardiac disease: use cautiously due to potential bradycardia or conduction disturbances.
  • Pregnancy: evaluate risk‑benefit before administration.
  • Concomitant calcium therapy: avoid simultaneous IV infusion to prevent precipitation.
  • Drug interactions: review other magnesium‑containing products before use.
  • Store at ambient temperature: keep in original container, protect from moisture and light.

Avoid Interactions

Magnesium sulfate may interact with several agents.

Major Interactions (Avoid)

  • Calcium gluconate: concurrent IV may precipitate calcium‑magnesium complexes.
  • Potassium‑sparing diuretics: increase risk of hypermagnesemia.
  • Neuromuscular blocking agents: may potentiate blockade.

Moderate Interactions (Monitor Closely)

  • Aminoglycoside antibiotics: may enhance nephrotoxicity.
  • Loop diuretics: increase renal magnesium loss, requiring close monitoring of serum levels.

Frequently Asked Questions

Magnesium Sulfuricum Bbp is indicated for the treatment of hypomagnesemia, general magnesium deficiency, eclampsia in pregnancy, and torsades de pointes, a specific type of ventricular tachycardia. It is used when rapid magnesium repletion is required to stabilize neuromuscular and cardiac function.

Magnesium sulfate heptahydrate releases magnesium ions that serve as cofactors for many enzymatic reactions, stabilize cell membranes, and oppose calcium‑mediated excitability. By increasing extracellular magnesium, it helps normalize nerve and muscle activity, supports cardiac electrical stability, and corrects electrolyte imbalances.

The dose of Magnesium Sulfuricum Bbp is determined by the prescribing clinician based on the patient’s clinical condition, serum magnesium level, renal function, and route of administration. Healthcare professionals calculate the appropriate amount and infusion rate for each individual case.

Magnesium sulfate is classified as a pregnancy category that requires a risk‑benefit assessment. It is commonly used for eclampsia under medical supervision, but the prescriber must evaluate maternal and fetal safety. Limited data are available for breastfeeding, so clinicians should consider potential exposure to the infant.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including cold‑chain if needed), and import documentation.

Magnesium Sulfuricum Bbp provides magnesium as a sterile injectable solution, allowing rapid intravenous or intramuscular delivery, which is advantageous in acute settings such as eclampsia or cardiac arrhythmias. Oral magnesium salts are slower to act and may have lower bioavailability, making injectables preferred for urgent correction.

The product should be stored at ambient temperature, protected from moisture and direct sunlight. Keep the vial in its original packaging until use, and inspect for particulate matter or discoloration before administration. Follow standard aseptic techniques when preparing the injection.

Magnesium Sulfuricum Bbp is administered by a qualified healthcare professional via intramuscular, intravenous, or subcutaneous injection. The route, infusion rate, and total dose are selected by the prescriber according to the indication, patient weight, and serum magnesium levels.

Serious risks include hypermagnesemia, which can cause respiratory depression, severe hypotension, cardiac arrest, and loss of deep tendon reflexes. Anaphylactic reactions are rare but possible. Continuous monitoring of vital signs and serum magnesium is essential during high‑dose or rapid infusions.

Patients with severe renal failure, uncontrolled heart block, or known hypersensitivity to magnesium sulfate should not receive this product. Caution is also advised for individuals on concurrent calcium therapy or those receiving other magnesium‑containing medications without appropriate monitoring.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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