Product image of Magnesium Sulfuricum Pharmamagist (Magnesium Sulfate Heptahydrate) supplied by GNH India

Magnesium Sulfuricum Pharmamagist

Active Ingredient:
Magnesium Sulfate Heptahydrate
Origin:
EU

Magnesium Sulfuricum Pharmamagist (Magnesium Sulfate Heptahydrate)

Magnesium sulfate heptahydrate, the active ingredient in Magnesium Sulfuricum Pharmamagist, is an electrolyte supplement presented as an injection solution for intravenous use. It treats magnesium deficiency and related electrolyte disturbances in hospitalized patients.

GNH India supplies Magnesium Sulfuricum Pharmamagist as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals worldwide.

Manufacturer / TM Owner

Pharmamagist Ltd.

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Indications & Clinical Uses

Magnesium Sulfuricum Pharmamagist is used to correct magnesium deficits and related electrolyte imbalances across several clinical scenarios.

  • Magnesium deficiency: restores normal serum magnesium levels and supports enzymatic functions.
  • Eclampsia prevention: provides magnesium ions that help prevent seizures in pre‑eclamptic patients.
  • Torsades de pointes and other arrhythmias: stabilises cardiac membranes to reduce ventricular ectopy.
  • Obstetric uterine relaxation: promotes smooth‑muscle relaxation during labor and delivery.

How It Works

  • Magnesium sulfate heptahydrate dissociates to release Mg2+ ions that act as essential cofactors for over 300 enzymatic reactions, stabilize cell membranes, and competitively antagonise calcium‑mediated excitability. The increased extracellular magnesium reduces neuronal firing, relaxes smooth muscle, and modulates cardiac electrophysiology, thereby correcting deficiency and providing therapeutic effects in arrhythmias and obstetric settings.

Side Effects

Adverse reactions may occur with intravenous magnesium administration.

Common Side Effects

  • Flushing or feeling of warmth.
  • Hypotension or mild blood pressure drop.
  • Nausea, headache, or transient dizziness.
  • Injection‑site pain or irritation.

Serious or Rare Side Effects

  • Severe hypotension or cardiovascular collapse.
  • Respiratory depression or apnea.
  • Cardiac arrest or profound arrhythmias.
  • Hypermagnesemia with neuromuscular weakness.
  • Anaphylactic or severe allergic reactions.

Precautions & Warnings

Magnesium Sulfuricum Pharmamagist requires careful patient assessment and monitoring.

  • Renal impairment: adjust or avoid use in patients with severe renal dysfunction.
  • Cardiac conduction disorders: monitor ECG and serum magnesium levels.
  • Concurrent calcium channel blockers: avoid co‑administration due to additive effects.
  • Obstetric use: employ only under obstetric supervision for eclampsia or uterine relaxation.
  • Serum monitoring: check magnesium concentrations regularly during prolonged therapy.
  • Store at 2-8°C: keep refrigerated, protect from light, do not freeze or shake.

Avoid Interactions

Magnesium sulfate can influence the activity of several other medicines.

Major Interactions (Avoid)

  • Neuromuscular blocking agents: potentiates muscle relaxation and may cause prolonged paralysis.
  • Calcium channel blockers: additive hypotensive effect can lead to severe blood pressure drop.

Moderate Interactions (Monitor Closely)

  • ACE inhibitors or ARBs: may enhance hypermagnesemia risk; monitor renal function.
  • Loop diuretics: increase magnesium loss; consider supplementation.
  • Antacids containing calcium or aluminum: reduce magnesium absorption and efficacy.

Frequently Asked Questions

Magnesium Sulfuricum Pharmamagist is an intravenous magnesium sulfate heptahydrate solution used to correct magnesium deficiency, prevent eclamptic seizures, manage certain cardiac arrhythmias such as torsades de pointes, and provide uterine relaxation during obstetric procedures.

After infusion, magnesium sulfate dissociates into Mg2+ ions that serve as cofactors for many enzymes, stabilize cell membranes, and antagonise calcium‑mediated excitability. This helps normalize neuromuscular transmission, relax smooth muscle, and stabilize cardiac electrophysiology.

The dosage is determined by the prescribing clinician based on the patient’s clinical condition, serum magnesium level, renal function, and therapeutic goal. No fixed regimen is provided here; the prescriber sets the appropriate infusion rate and total dose.

Magnesium sulfate is commonly used in obstetric care for eclampsia prevention and uterine relaxation. However, safety information is limited, and use should follow obstetric guidelines. Breastfeeding mothers should consult their healthcare provider, as magnesium can be excreted in milk.

Submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including cold‑chain if needed), and import documentation.

Magnesium Sulfuricum Pharmamagist is a sterile injectable form, offering rapid correction of magnesium levels compared with oral magnesium salts, which have slower absorption and may cause gastrointestinal upset. It is preferred in acute, hospital‑based settings where precise dosing and immediate effect are required.

The solution must be stored refrigerated at 2‑8 °C, protected from light, and should never be frozen or shaken. Keep the vial in its original packaging until use and discard any product that appears discolored or contains particles.

The product is administered intravenously by a qualified healthcare professional. It is typically given as a controlled infusion over a specified period, with continuous monitoring of vital signs and serum magnesium levels throughout the administration.

Serious risks include severe hypotension, respiratory depression, cardiac arrest, hypermagnesemia leading to neuromuscular weakness, and rare anaphylactic reactions. Prompt recognition and supportive measures are essential if any of these events occur.

Patients with severe renal failure, uncontrolled heart block, or known hypersensitivity to magnesium sulfate should avoid this product. It should also be used with caution in individuals receiving neuromuscular blockers, calcium channel blockers, or other agents that may potentiate its effects.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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