Magnesiumsulfat Kalceks (Magnesium Sulfate Heptahydrate)

Magnesium sulfate releases magnesium ions that serve as cofactors for many enzymes, regulate calcium channels, and stabilize cell membranes. This reduces neuronal excitability, relaxes smooth muscle, and supports cardiac electrical stability, helping to correct electrolyte disturbances and protect neuromuscular function.

The specific dose and infusion rate are determined by the prescribing clinician based on the patient’s condition, weight, renal function and laboratory values. Healthcare professionals set the regimen to achieve therapeutic magnesium levels while avoiding toxicity.

Magnesium sulfate is classified as a pregnancy‑category drug only when the therapeutic benefit justifies potential risks. It is commonly used for eclampsia under medical supervision. Limited data exist for breastfeeding, so clinicians weigh benefits against possible infant exposure.

To place an order, submit an enquiry on the product page at gnhindia.com, indicating the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including cold‑chain if needed) and import documentation.

Compared with magnesium chloride or magnesium gluconate, magnesium sulfate offers higher solubility for intravenous use and a well‑established safety profile for obstetric and cardiac indications. Oral magnesium salts are less suitable for rapid correction of severe deficiency, whereas the sulfate form is preferred for acute, controlled administration.

Store the product below 25 °C in its original packaging, protecting it from moisture and direct light. Do not freeze. Before use, inspect the solution for particulate matter or discoloration and ensure aseptic technique when drawing up for injection.

The preparation is given by intramuscular, intravenous or subcutaneous injection under the supervision of qualified healthcare personnel. The route, infusion speed and total volume are selected by the prescriber according to the clinical indication and patient tolerance.

Serious adverse events include severe hypotension, cardiac arrhythmias, respiratory depression and hypermagnesemia, which can lead to loss of deep‑tendon reflexes, muscle paralysis and, in extreme cases, cardiac arrest. Continuous monitoring of vital signs and serum magnesium is essential during therapy.

Patients with advanced heart block, severe renal failure, or known hypersensitivity to magnesium sulfate should avoid its use. Caution is also advised for individuals on high‑dose calcium channel blockers, neuromuscular blockers or other agents that may potentiate magnesium’s effects.