Product image of Magnurol (Terazosin Hydrochloride) supplied by GNH India

Magnurol

Active Ingredient:
Terazosin Hydrochloride
Origin:
EU

Magnurol (Terazosin Hydrochloride)

Terazosin, the active ingredient in Magnurol, is a Alpha-1 adrenergic blocker presented as a tablet for oral use. It is employed to lower high blood pressure and to improve urinary flow in men with an enlarged prostate.
GNH India supplies Magnurol as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Amdipharm Limited

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Indications & Clinical Uses

Terazosin acts on the alpha‑1 adrenergic pathway to manage cardiovascular and urological conditions.

  • Hypertension: reduces systemic vascular resistance to lower blood pressure.
  • Benign prostatic hyperplasia: relaxes smooth muscle in the prostate and bladder neck to improve urine flow.
  • Elevated systolic blood pressure: assists patients in reaching target systolic levels as part of antihypertensive therapy.

How It Works

  • Terazosin selectively antagonizes alpha‑1 adrenergic receptors on vascular smooth muscle and prostatic tissue. By blocking these receptors, it prevents norepinephrine‑induced vasoconstriction, producing vasodilation and decreased peripheral resistance. In the prostate, receptor blockade relaxes smooth muscle, lowering urethral resistance and facilitating urinary passage.

Side Effects

Terazosin may cause a range of adverse reactions, which are categorized by frequency and severity.

Common Side Effects

  • Dizziness or light‑headedness
  • Headache
  • Fatigue
  • Nasal congestion
  • Peripheral edema
  • Nausea

Serious or Rare Side Effects

  • Orthostatic hypotension leading to fainting
  • Priapism (prolonged erection)
  • Severe liver injury (rare)
  • Anaphylactic reaction
  • Exacerbation of heart failure
  • Syncope

Precautions & Warnings

Before initiating therapy, clinicians should evaluate several safety considerations.

  • Blood pressure monitoring: check baseline and periodic readings.
  • Prostate assessment: confirm diagnosis of BPH before use.
  • Concomitant antihypertensives: adjust doses to avoid excessive hypotension.
  • Hepatic function: use caution in patients with liver impairment.
  • Discontinuation: avoid abrupt stopping to prevent rebound hypertension.
  • Store at ambient temperature: keep in original container, protect from moisture.

Avoid Interactions

Terazosin can interact with other medicines, altering its efficacy or safety profile.

Major Interactions (Avoid)

  • Other alpha‑1 blockers (e.g., prazosin) – additive hypotensive effect.
  • Potent CYP3A4 inhibitors (e.g., ketoconazole) – increased plasma levels.
  • PDE5 inhibitors (e.g., sildenafil) – risk of severe hypotension.

Moderate Interactions (Monitor Closely):\n- Lithium – possible increase in lithium concentrations.

  • Diuretics – may enhance orthostatic blood pressure drops.

Frequently Asked Questions

Magnurol contains terazosin, which is prescribed to lower high blood pressure (hypertension) and to relieve urinary symptoms caused by an enlarged prostate (benign prostatic hyperplasia). It works by relaxing blood vessels and prostate smooth muscle, improving blood flow and urine passage.

Terazosin selectively blocks alpha‑1 adrenergic receptors on vascular smooth muscle and prostatic tissue. This blockade prevents norepinephrine‑induced contraction, leading to vasodilation that lowers blood pressure and to relaxation of prostate and bladder neck muscles, which eases urinary flow.

The specific dose of Magnurol is determined by the prescribing healthcare professional based on the individual’s medical condition, response to therapy, and other factors. Patients should follow the prescriber’s instructions and not adjust the dose without medical guidance.

Safety data for terazosin in pregnancy and lactation are limited, and the product is generally not recommended for use in pregnant or nursing women unless the potential benefit outweighs the risk. Clinicians should evaluate each case carefully.

To place an order, submit an enquiry on the Magnurol product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details, and any necessary import documentation.

Magnurol (terazosin) belongs to the alpha‑1 blocker class, which differs from ACE inhibitors, ARBs, calcium‑channel blockers, and diuretics. It primarily reduces peripheral resistance and also treats BPH, offering a dual benefit not provided by many other antihypertensives.

Magnurol tablets should be stored at ambient temperature, below 25 °C. Keep them in the original packaging, protect from moisture and direct sunlight, and store out of reach of children.

Magnurol is taken orally, usually with a full glass of water. It can be taken with or without food, but patients should follow the prescriber’s guidance on timing and whether to take it in the morning or evening.

The most serious risks include severe orthostatic hypotension that can cause fainting, priapism (a prolonged erection), and rare cases of liver injury or anaphylaxis. Patients should seek immediate medical attention if they experience sudden dizziness, chest pain, or unusual erections.

Magnurol is contraindicated in patients with known hypersensitivity to terazosin or any component of the formulation, and it should be used with caution in individuals with severe liver disease, recent myocardial infarction, or those already on multiple alpha‑blockers.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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