Product image of Magnyl (Acetylsalicylic Acid) supplied by GNH India

Magnyl

Active Ingredient:
Acetylsalicylic Acid
Origin:
EU

Magnyl (Acetylsalicylic Acid)

Acetylsalicylic acid, the active ingredient in Magnyl, is a non‑steroidal anti‑inflammatory drug presented as an oral tablet for oral use. It provides analgesic, antipyretic, anti‑inflammatory and antiplatelet effects for adults requiring pain relief, fever reduction or cardiovascular protection.
GNH India supplies Magnyl as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Orifarm Healthcare A/S

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Indications & Clinical Uses

Magnyl, an NSAID that inhibits platelet aggregation and prostaglandin synthesis, is employed in several clinical contexts:

  • Pain relief: reduces mild to moderate pain such as headache or musculoskeletal discomfort.
  • Fever reduction: lowers elevated body temperature associated with infection or inflammation.
  • Inflammation reduction: alleviates inflammatory swelling in conditions like arthritis.
  • Prevention of arterial thrombosis: lowers risk of recurrent myocardial infarction or ischemic stroke in patients with established cardiovascular disease.

How It Works

  • Acetylsalicylic acid irreversibly acetylates the cyclooxygenase‑1 (COX‑1) enzyme in platelets and peripheral tissues. This blocks conversion of arachidonic acid to thromboxane A2 and prostaglandins, decreasing platelet aggregation, pain signalling, fever generation, and inflammatory responses.

Side Effects

Adverse reactions may vary in frequency and severity.

Common Side Effects

  • Gastrointestinal discomfort: dyspepsia, abdominal pain.
  • Nausea or vomiting.
  • Minor bruising or bleeding from gums.
  • Mild headache.
  • Rash or mild skin irritation.

Serious or Rare Side Effects

  • Gastrointestinal ulceration or bleeding.
  • Severe hypersensitivity reactions, including anaphylaxis.
  • Hemorrhagic stroke.
  • Renal impairment or failure.
  • Hepatotoxicity.
  • Reye's syndrome in children with viral illness.

Precautions & Warnings

Before using Magnyl, consider the following safety measures:

  • Assess bleeding risk: avoid in patients with active ulcers or coagulopathy.
  • Evaluate renal function: adjust use in chronic kidney disease.
  • Monitor hepatic status: caution in liver impairment.
  • Review concomitant NSAIDs or anticoagulants: increased bleeding potential.
  • Avoid use in children with viral infections: risk of Reye's syndrome.
  • Store at ambient temperature: keep in original container, protect from moisture and direct sunlight.

Avoid Interactions

Magnyl can interact with several drug classes, requiring careful management.

Major Interactions (Avoid)

  • Anticoagulants (e.g., warfarin, direct oral anticoagulants): heightened bleeding risk.
  • Other NSAIDs or COX‑2 inhibitors: additive gastrointestinal toxicity.
  • Corticosteroids: increased ulceration potential.

Moderate Interactions (Monitor Closely)

  • Selective serotonin reuptake inhibitors (SSRIs): modestly increased bleeding.
  • ACE inhibitors or diuretics: possible reduction in renal perfusion.
  • Methotrexate: decreased clearance leading to toxicity.

Frequently Asked Questions

Magnyl is used to relieve mild to moderate pain, reduce fever, lessen inflammation in disorders such as arthritis, and to prevent arterial thrombosis in patients with a history of myocardial infarction or ischemic stroke.

Acetylsalicylic acid irreversibly blocks the COX‑1 enzyme, which stops the formation of thromboxane A2 and prostaglandins. This action reduces platelet aggregation, pain signaling, fever, and inflammation.

The appropriate dose of Magnyl is determined by the prescribing healthcare professional based on the individual’s condition, age, and response to therapy. Patients should follow the prescriber’s instructions.

Safety of Magnyl in pregnancy or lactation has not been fully established. It should only be used if the potential benefit justifies the possible risk, and this decision must be made by a qualified healthcare provider.

To order Magnyl, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Magnyl (acetylsalicylic acid) provides antiplatelet activity through irreversible COX‑1 inhibition, whereas other agents like clopidogrel act on the P2Y12 receptor. Aspirin is often chosen for its low cost and extensive evidence in secondary cardiovascular prevention, while alternative agents may be preferred in aspirin‑intolerant patients.

Store Magnyl at ambient temperature, preferably below 25 °C. Keep the tablets in the original packaging, protect them from moisture, heat and direct sunlight to maintain stability.

Magnyl is taken orally with a glass of water. It may be taken with or without food, but taking it with food can reduce gastrointestinal discomfort in some individuals.

The most serious risks include gastrointestinal bleeding or ulceration, severe allergic reactions such as anaphylaxis, hemorrhagic stroke, and, in children with viral infections, the rare but fatal Reye's syndrome.

Magnyl should be avoided in individuals with active peptic ulcer disease, known hypersensitivity to aspirin or other NSAIDs, uncontrolled bleeding disorders, and in children or teenagers with viral illnesses due to the risk of Reye's syndrome.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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