Product image of Magrilan (Fluoxetine) supplied by GNH India

Magrilan

Active Ingredient:
Fluoxetine
Origin:
EU

Magrilan (Fluoxetine)

Fluoxetine, the active ingredient in Magrilan, is a selective serotonin reuptake inhibitor (SSRI) presented as an oral tablet for oral use. It is prescribed to treat major depressive disorder and several related psychiatric conditions in adult patients.

GNH India supplies Magrilan as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to stringent quality standards and provides reliable sourcing for regulated markets. Our global distribution network ensures timely delivery and compliance with local regulatory requirements.

Manufacturer / TM Owner

Medochemie Ltd.

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

Fluoxetine is used to treat several psychiatric disorders by modulating serotonin pathways.

  • Major depressive disorder: reduces depressive symptoms and improves mood.
  • Obsessive‑compulsive disorder: lessens intrusive thoughts and compulsive behaviors.
  • Panic disorder: decreases frequency and severity of panic attacks.
  • Bulimia nervosa: helps reduce binge‑eating episodes and associated urges.
  • Premenstrual dysphoric disorder: alleviates mood swings and physical symptoms linked to the menstrual cycle.

How It Works

  • Fluoxetine selectively inhibits the serotonin transporter (SERT) on presynaptic neurons, blocking reuptake of serotonin (5‑HT) from the synaptic cleft. This increases extracellular serotonin concentrations, enhancing serotonergic neurotransmission throughout the central nervous system, which contributes to mood stabilization and reduction of anxiety‑related symptoms. The drug’s long half‑life maintains steady serotonin levels, and its minimal effect on other neurotransmitter systems accounts for its relatively specific therapeutic profile.

Side Effects

Fluoxetine may cause a range of adverse reactions, varying from mild to severe.

Common Side Effects

  • Nausea: mild gastrointestinal upset.
  • Headache: transient cranial discomfort.
  • Insomnia: difficulty falling or staying asleep.
  • Dry mouth: reduced salivation.
  • Sexual dysfunction: decreased libido or delayed orgasm.
  • Diarrhea: loose stools.

Serious or Rare Side Effects

  • Serotonin syndrome: agitation, hyperthermia, and neuromuscular abnormalities.
  • Suicidal thoughts: increased risk especially in young adults.
  • Severe allergic reaction: rash, swelling, or anaphylaxis.
  • Hyponatremia: low blood sodium causing confusion.
  • QT prolongation: cardiac rhythm disturbances.

Precautions & Warnings

When prescribing fluoxetine, clinicians should consider several safety precautions to minimize risks.

  • Assess for suicidal ideation: monitor patients, especially during early treatment and dose changes.
  • Evaluate hepatic function: adjust use in patients with severe liver impairment.
  • Review psychiatric history: caution in bipolar disorder due to risk of mania.
  • Avoid abrupt discontinuation: taper gradually to prevent discontinuation syndrome.
  • Consider drug interactions: check concomitant serotonergic agents and CYP2D6 inhibitors.
  • Store at ambient temperature: keep in original packaging, protect from moisture and light.

Avoid Interactions

Fluoxetine interacts with several medicines; understanding the interaction level guides clinical decisions.

Major Interactions (Avoid)

  • Monoamine oxidase inhibitors (MAOIs): risk of serotonin syndrome if combined.
  • Thioridazine or pimozide: can cause cardiac arrhythmias and increased plasma levels.

Moderate Interactions (Monitor Closely)

  • NSAIDs: increased bleeding risk.
  • Warfarin: enhanced anticoagulant effect, monitor INR.
  • Oral contraceptives: reduced efficacy, consider alternative contraception.
  • Alcohol: may intensify central nervous system effects.

Frequently Asked Questions

Magrilan, containing fluoxetine, is indicated for major depressive disorder, obsessive‑compulsive disorder, panic disorder, bulimia nervosa, and premenstrual dysphoric disorder. In each condition the medication helps to improve mood, reduce compulsive thoughts, lessen panic attacks, control binge‑eating behaviors, or stabilize menstrual‑related mood swings.

Fluoxetine works by selectively blocking the serotonin transporter on presynaptic nerve endings. This inhibition prevents serotonin reuptake, leading to higher levels of serotonin in the synaptic cleft and prolonged serotonergic signaling, which is associated with improved mood and reduced anxiety.

The appropriate dose of Magrilan is determined by the prescribing clinician based on the specific diagnosis, patient age, severity of symptoms, and individual response. Physicians may start with a low dose and adjust gradually, following established clinical guidelines and patient monitoring.

The safety of fluoxetine in pregnancy and lactation has not been definitively established. Healthcare providers weigh potential benefits against possible risks to the fetus or infant, and may consider alternative treatments or close monitoring if use is deemed necessary.

To order Magrilan, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details, and any required import documentation.

Magrilan (fluoxetine) belongs to the SSRI class, offering a relatively long half‑life and a favorable interaction profile compared with some older antidepressants such as tricyclics. Compared with other SSRIs, fluoxetine may have a slightly higher risk of activation symptoms but is often chosen for its once‑daily dosing and lower weight‑gain potential.

Magrilan should be stored at ambient temperature, below 25 °C, in its original container. Keep the product away from excess moisture, direct sunlight, and heat sources to maintain tablet integrity and potency throughout its shelf life.

Magrilan is taken orally as a tablet, usually with or without food. Patients should swallow the tablet whole with water and follow the dosing schedule prescribed by their healthcare professional, avoiding missed doses when possible.

The most serious risks include serotonin syndrome—a potentially life‑threatening condition marked by agitation, fever, and muscle rigidity—and an increased risk of suicidal thoughts or behaviors, particularly in young adults during the early weeks of therapy. Prompt medical attention is required if these symptoms appear.

Magrilan is contraindicated in patients currently taking monoamine oxidase inhibitors, those with known hypersensitivity to fluoxetine or any tablet excipients, and individuals with a history of severe allergic reactions to SSRIs. Caution is also advised for patients with uncontrolled narrow‑angle glaucoma or severe hepatic impairment.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Related Products

Other formulations containing Fluoxetine

A

A
A

A
A

A
A

A

Browse all products →

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Regulatory recognitions

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.

SGS GSDP Certification

GSDP Compliant from SGS

URS ISO 9001

URS ISO 9001 Certification

FDA Maharashtra

Licensed by FDA Maharashtra

IEC License DGFT

IEC License issued by DGFT