Product image of Magromag (Nitrofurantoin) supplied by GNH India

Magromag

Active Ingredient:
Nitrofurantoin
Origin:
EU

Magromag (Nitrofurantoin)

Nitrofurantoin, the active ingredient in Magromag, is a nitrofuran antibiotic presented as an oral dosage form for oral use. It treats uncomplicated urinary tract infections in adult patients.
GNH India supplies Magromag as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Olpha As

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Indications & Clinical Uses

Nitrofurantoin is indicated for infections of the urinary tract and related conditions.

  • Uncomplicated urinary tract infection: reduces bacterial load and resolves symptoms.
  • Acute cystitis: provides bacteriostatic/bactericidal activity against common uropathogens.
  • Recurrent UTI prophylaxis: helps prevent recurrence when used as prescribed.

How It Works

  • Nitrofurantoin is reduced by bacterial flavoproteins to reactive intermediates that inhibit enzymes involved in carbohydrate metabolism and interfere with cell‑wall synthesis, producing bacteriostatic or bactericidal effects against urinary pathogens.

Side Effects

Adverse reactions may occur with nitrofurantoin therapy.

Common Side Effects

  • Nausea: mild to moderate stomach upset.
  • Vomiting: occasional expulsion of stomach contents.
  • Loss of appetite: reduced desire to eat.
  • Abdominal pain: cramping or discomfort in the stomach area.
  • Diarrhoea: loose stools occurring during treatment.
  • Headache: mild to moderate head pain.

Serious or Rare Side Effects

  • Pulmonary toxicity: interstitial lung disease or acute respiratory distress.
  • Hepatic injury: elevated liver enzymes or hepatitis.
  • Hemolytic anemia: especially in patients with G6PD deficiency.
  • Severe skin reactions: Stevens‑Johnson syndrome or toxic epidermal necrolysis.
  • Peripheral neuropathy: tingling or numbness in extremities.
  • Eosinophilic pneumonia: inflammatory lung condition with eosinophil accumulation.

Precautions & Warnings

Before prescribing nitrofurantoin, consider the following safety measures.

  • Renal function: assess creatinine clearance to ensure adequate excretion.
  • Pregnancy: category B; use only when benefit outweighs potential risk.
  • Elderly patients: monitor for reduced renal clearance and increased exposure.
  • G6PD deficiency: avoid due to risk of hemolysis.
  • Drug interactions: review concomitant medications for potential effects.
  • Store at ambient temperature: keep in the original pack, protect from moisture and light.

Avoid Interactions

Nitrofurantoin may interact with other medicines; some require avoidance while others need monitoring.

Major Interactions (Avoid)

  • Antacids containing magnesium or aluminium: reduce nitrofurantoin absorption.
  • Probenecid: decreases renal excretion, increasing toxicity risk.
  • Cimetidine: may raise serum nitrofurantoin levels.

Moderate Interactions (Monitor Closely)

  • Warfarin: nitrofurantoin can enhance anticoagulant effect.
  • Methenamine: additive urinary‑tract effects may increase irritation.
  • Fluoroquinolones: overlapping toxicity profiles warrant careful observation.

Frequently Asked Questions

Magromag contains nitrofurantoin, which is used to treat uncomplicated urinary tract infections caused by susceptible bacteria. It is prescribed for adult patients who need an oral antibacterial agent targeting the urinary tract.

Nitrofurantoin is reduced by bacterial enzymes to reactive intermediates that damage bacterial DNA, inhibit carbohydrate metabolism, and disrupt cell‑wall synthesis. These actions result in bacteriostatic or bactericidal effects against common urinary pathogens.

The dosage of Magromag is determined by the prescribing clinician based on the patient’s condition, renal function, and local treatment guidelines. Patients should follow the prescriber’s instructions and not alter the dose on their own.

Nitrofurantoin is classified as pregnancy category B, indicating no evidence of risk in animal studies but limited human data. It may be used during pregnancy only if the potential benefit justifies the risk. Use while breastfeeding should be discussed with a healthcare professional.

To order Magromag, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Magromag (nitrofurantoin) is a nitrofuran antibiotic that offers targeted activity against many common uropathogens, especially Escherichia coli. Compared with broader‑spectrum agents such as trimethoprim‑sulfamethoxazole, nitrofurantoin has a lower risk of promoting resistance but is limited to uncomplicated infections and requires adequate renal function.

Magromag should be stored at ambient temperature, below 25 °C. Keep the product in its original packaging, protect it from moisture and direct sunlight, and ensure the container is tightly closed to maintain stability.

Magromag is taken orally, usually with a full glass of water. It can be taken with or without food, but patients should follow the prescriber’s guidance regarding timing relative to meals to optimise absorption.

Serious risks include pulmonary toxicity (interstitial lung disease), hepatic injury, hemolytic anemia in patients with G6PD deficiency, severe skin reactions such as Stevens‑Johnson syndrome, and peripheral neuropathy. Patients should seek immediate medical attention if they experience respiratory difficulty, jaundice, unusual skin rash, or numbness.

Magromag should be avoided in patients with severe renal impairment (creatinine clearance < 30 mL/min), known hypersensitivity to nitrofurantoin, or a history of G6PD deficiency. Caution is also advised for individuals with a prior history of pulmonary or hepatic reactions to nitrofurantoin.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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